Product Identification

Product Name

Ipratropium bromide

Synonyms

8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, (endo,syn)-, bromide
8-Isopropylatropinium bromide
Atropine isopropyl bromide
N-Isopropylatropinium bromide
N-Isopropylnoratropinium bromomethylate

CAS

22254-24-6

Formula

C20H30BrNO3

Molecular Weight

412.37

EINECS

244-873-8

RTECS

YM3700000

RTECS Class

Drug; Reproductive Effector; Human Data; Primary Irritant

Merck

12,5089

Beilstein/Gmelin

6035562

Beilstein Reference

6-21

Physical and Chemical Properties

Appearance

White powder.

Solubility in water

10 g/L

Melting Point

229 - 231

Usage

Nonselective muscarinic acetylcholine receptor antagonist and bronchodilator.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed.

Hazards Identification

Inhalation

Harmful if inhaled. Material is irritating to mucous membranes and upper respiratory tract.

Skin

Causes skin irritation. Harmful if absorbed through skin.

Eyes

Causes eye irritation.

Ingestion

Harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

20/22 36

EC Safety Phrase

26 36

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles.

Respirators

Government approved respirator.

Exposure Effects

Harmful by inhalation and if swallowed. Irritating to eyes. Target organ(s): Nerves.

Fire Fighting Measures

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable at normal temperatures and pressures.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen bromide gas.