Product Identification

Product Name

5-Bromonicotinic acid 10-methoxy-1,6-dimethylergoline-8-methyl ester

Synonyms

1,6-Dimethyl-8b-(5-bromonicotinoyloxymethyl)-10a-methoxyergoline
Vasospan

CAS

27848-84-6

Formula

C24H26BrN3O3

Molecular Weight

484.39

EINECS

248-694-6

RTECS

KE6341000

RTECS Class

Drug; Reproductive Effector

Merck

12,6580

Beilstein/Gmelin

4828393

Beilstein Reference

6-23

Physical and Chemical Properties

Solubility in water

Insoluble

Vapor Pressure

4E-14 (25 C)

pKa/pKb

6.22 (pKb)

Heat Of Vaporization

88.6 kJ/mol

Usage

Cerebral and peripheral vasodilator.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Store at 2 - 8 C.

Hazards Identification

Inhalation

May be harmful if inhaled.

Skin

May be harmful if absorbed through the skin.

Ingestion

Harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

22

EC Safety Phrase

36

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.

Exposure Effects

Harmful. Harmful if swallowed.

Fire Fighting Measures

Flash Point

313

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides.