Product Identification

Product Name

p-bromophenylamine

Synonyms

4-Bromobenzenamine
p-Bromophenylamine

CAS

106-40-1

Formula

C6H6BrN

Molecular Weight

172.03

EINECS

203-393-9

RTECS

BW9280000

RTECS Class

Mutagen

Merck

13,1388

Beilstein/Gmelin

742031

Beilstein Reference

4-12-00-01497

EC Class

toxic, dangerous for the environment

Physical and Chemical Properties

Appearance

Colorless rhombic crystals, sweet odor.

Solubility in water

Insoluble

Melting Point

62 - 64

Boiling Point

123.9 - 124.3 (14 torr)

Vapor Pressure

.2

Density

1.799 g/cm3 (20 C)

pKa/pKb

9.98 (pKb)

Partition Coefficient

2.26

Usage

In prepn of azo dyes, condensed with formaldehyde in prepn of dihydroquinazolines.

Saturation Concentration

224 ppm (0.02%) at 25 C (calculated)

Vapor Density

5.9

Refractive Index

1.5835 (99.6 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.

Skin

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool place in the original container and protect from sunlight. Store in a tightly closed container.

Handling

Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Keep container tightly closed. Do not get on skin or in eyes. Do not ingest or inhale. Wash clothing before reuse.

Hazards Identification

Inhalation

May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Inhalation of aniline causes anoxia due to the formation of methemoglobinemia.

Skin

May cause severe skin irritation.

Eyes

May cause severe eye irritation. May result in corneal injury.

Ingestion

Harmful if swallowed. May cause methemoglobinemia, cyanosis, convulsions, and death. May cause severe digestive tract irritation with abdominal pain, nausea, vomiting and diarrhea.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 20/21/22 33

EC Safety Phrase

S 28 36/37

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause liver and kidney damage. Prolonged exposure may cause anemia and methemoglobinemia, characterized by dizziness, drowsiness, headache, breath shortness, cyanosis, rapid heart rate and chocolate-brown colored blood.

Fire Fighting Measures

Flash Point

>112

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Reduce airborne dust and prevent scattering by moistening with water. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

9

Incompatibilities

Acids, acid chlorides, acid anhydrides, chloroformates, strong oxidizing agents, and sunlight.

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen bromide, nitrogen.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2811

Hazard Class

6.1

Packing Group

I; II; III

HS Code

2921 42 10