Product Identification

Product Name

1,8-Dihydroxy-3-methylanthraquinone

Synonyms

1,8-Dihydroxy-3-methylanthracene-9,10-dione
2-Methyl-4,5-dihydroxyanthraquinone
3-Methylchrysazin
Chrysophanic acid
Chrysophanol
Turkey Rhubarb

CAS

481-74-3

Formula

C15H10O4

Molecular Weight

254.24

EINECS

207-572-2

RTECS

CB6725000

RTECS Class

Mutagen

Merck

12,2318

Beilstein/Gmelin

1252300

Beilstein Reference

4-08-00-03277

Physical and Chemical Properties

Appearance

Golden yellow plates or brown powder. Pale yellow aqueous solutions turn red on addition of alkali. Solutions in concentrated sulfuric acid are red.

Solubility in water

Insoluble

Melting Point

196 - 197

Boiling Point

480

Vapor Pressure

3E-10 (25 C)

Density

0.92 g/cm3 (25C)

pKa/pKb

6.34 (pKa)

Partition Coefficient

4.26

Heat Of Vaporization

78.5 kJ/mol

Usage

Dye.

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from oxidizing agents.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.

Hazards Identification

Inhalation

Causes respiratory tract irritation. Causes irritation of mucous membrane. Exposure may cause coughing, breathing difficulty, and possible pulmonary edema.

Skin

Causes skin irritation.

Eyes

Causes eye irritation. May cause chemical conjunctivitis.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Effects may be delayed.

Fire Fighting Measures

Flash Point

264

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.