Product Identification

Product Name

Isocyanic acid 3,4-dichlorophenyl ester

Synonyms

3,4-Dichlorophenyl isocyanate

CAS

102-36-3

Formula

C7H3Cl2NO

Molecular Weight

188.01

EINECS

203-026-2

RTECS

NQ8760000

RTECS Class

Other

Beilstein/Gmelin

608325

Beilstein Reference

3-12-00-01405

EC Class

toxic, irritant, sensitizing

Physical and Chemical Properties

Appearance

White to yellow crystalline solid with an irritating odor, lachrymator.

Solubility in water

Insoluble

Melting Point

38 - 41

Boiling Point

234

Vapor Pressure

0.06 (25 C)

Partition Coefficient

4.01

Heat Of Vaporization

47.0 kJ/mol

Usage

Chemical intermediate, organic synthesis.

Saturation Concentration

263 ppm (0.03%) at 20 C (calculated)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.

Hazards Identification

Inhalation

Causes respiratory tract irritation. Can produce delayed pulmonary edema.

Skin

Causes skin irritation.

Eyes

Causes eye irritation. May cause chemical conjunctivitis.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea.

Hazards

Inhalation of dust is poisonous; fire may produce irritating or poisonous gases.

EC Risk Phrase

R 23/25 36/37/38 42

EC Safety Phrase

S 22 26 36/37/39 45

UN (DOT)

2250

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear safety glasses and chemical goggles if splashing is possible. Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Exposure Effects

Effects may be delayed.

Fire Fighting Measures

Flash Point

106

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Upper exp. limit

8.6

Lower exp. limit

1.6

Fire Potential

Combustible material: may burn but does not ignite readily.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.

Stability and Reactivity

Disposal Code

9

Incompatibilities

Incompatible with many classes of compounds, reacting exothermically to release toxic gases Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat.

Stability

Stable under normal temperatures and pressures. Stable at room temperature in closed containers under normal storage and handling conditions.

Decomposition

Hydrogen chloride, hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Combustion Products

Fire will produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2250

Hazard Class

6.1

Packing Group

II

HS Code

2929 10 90