Product Identification

Product Name

3-Cyanopyridine

Synonyms

3-Azabenzonitrile
3-Cyanopyridine
3-Pyridyl cyanide
3-Pyridylcarbonitrile
Nicotinic acid nitrile
Nicotinonitrile

CAS

100-54-9

Formula

C6H4N2

Molecular Weight

104.11

EINECS

202-863-0

RTECS

QT3030000

RTECS Class

Other

Beilstein/Gmelin

65995

Beilstein Reference

4-17-00-01442

EC Class

harmful, irritant

Physical and Chemical Properties

Appearance

Needles from petroleum ether.

Solubility in water

140 g/L

Melting Point

48 - 51

Boiling Point

206.2

Vapor Pressure

.3

Density

1.1590 g/cm3 (25 C)

pKa/pKb

12.61 (pKb)

Partition Coefficient

.36

Heat Of Vaporization

43.9 kJ/mol

Usage

Org synthesis.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use only in a well ventilated area. Use with adequate ventilation. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale.

Hazards Identification

Inhalation

Effects may be delayed. Causes respiratory tract irritation.

Skin

Causes severe skin irritation. Effects may be delayed.

Eyes

Causes severe eye irritation.

Ingestion

Causes gastrointestinal tract irritation. Effects may be delayed. May be harmful if swallowed.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 22

EC Safety Phrase

S 22 36/37

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

No data were available to assess the potential effects of exposure to this agent during pregnancy or lactation. <br>Animal studies on chick for substituted pyridines have shown teratogenicity. Injected chicken eggs develop leg and skeletal malformations.

Fire Fighting Measures

Flash Point

88

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.

Stability and Reactivity

Disposal Code

6

Incompatibilities

Oxidizing agents

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2811

Hazard Class

6.1

Packing Group

I; II; III

HS Code

2933 39 99