Product Identification

Product Name

4-Dimethylaminopyridine

Synonyms

4-Dimethylaminopyridine
DMAP
gamma-(Dimethylamino)pyridine
N,N-Dimethylpyridin-4-amine
Pyridine, 4-(dimethylamino)-

CAS

1122-58-3

Formula

C7H10N2

Molecular Weight

122.17

EINECS

214-353-5

RTECS

US9230000

RTECS Class

Other

Beilstein/Gmelin

110354

Beilstein Reference

5-22-09-00112

EC Class

toxic, irritant

Physical and Chemical Properties

Appearance

Off white to brown solid.

Solubility in water

Very soluble

Melting Point

109 - 111

Boiling Point

195

Vapor Pressure

0.43 (25 C)

Density

0.41 g/cm3 (20 C)

pKa/pKb

4.48 (pKb)

Partition Coefficient

1.34

Heat Of Vaporization

43.1 kJ/mol

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Discard contaminated clothing in a manner which limits further exposure.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed.

Handling and Storage

Storage

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use with adequate ventilation. Discard contaminated shoes.

Hazards Identification

Ingestion

Harmful if swallowed. May cause severe and permanent damage to the digestive tract.

Inhalation

May cause severe irritation of the respiratory tract with possible burns.

Skin

May be fatal if absorbed through the skin. Causes skin burns.

Eyes

Causes eye burns.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 23/24/25 36/37/38

EC Safety Phrase

S 26 28 36/37/39 45

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Flash Point

124

Autoignition

420

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use water spray, dry chemical, or carbon dioxide.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

3

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2811

Hazard Class

6.1

Packing Group

I; II; III

HS Code

2933 39 99