Product Identification

Product Name

4-Aminopyridine

Synonyms

4-Aminopyridine

CAS

504-24-5

Formula

C5H6N2

Molecular Weight

94.12

EINECS

207-987-9

RTECS

US1750000

RTECS Class

Agricultural Chemical and Pesticide; Human Data

Merck

13,3964

Beilstein/Gmelin

105782

Beilstein Reference

5-22-09-00106

EC Class

very toxic, irritant

Physical and Chemical Properties

Appearance

White crystalline material with no odor.

Solubility in water

72 g/L

Melting Point

157 - 160

Boiling Point

273

Vapor Pressure

.8

Density

1.25 g/cm3

pKa/pKb

4.83 (pKb)

Partition Coefficient

-.76

Heat Of Vaporization

90.02 kJ/mol

Heat Of Combustion

-2864 kJ/mol

Usage

Avicide.

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Use only in a chemical fume hood.

Hazards Identification

Inhalation

Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. May cause severe headaches, nausea, increased blood pressure, weakness, convulsions, and a stuporous state.

Skin

Causes skin irritation. May be fatal if absorbed through the skin. Substance is rapidly absorbed through the skin. Causes symptoms similar to those of inhalation. Causes redness and pain.

Eyes

Causes eye irritation. Causes redness and pain.

Ingestion

May be fatal if swallowed. May cause irritation of the digestive tract. Poison by ingestion. May cause effects similar to those for inhalation exposure. An oral dose of 590 mg/kg of 4-aminopyridine in a man produced shortness of breath, nausea, vomiting, hallucinations and distorted perception. Affects the CNS to produce tremor, excitability and convulsions.

Hazards

Material may produce irritating or poisonous gases in fire. Runoff from fire control water may give off irritating or poisonous gases.

EC Risk Phrase

R 28 23/24 33 36/37/38 51/53

EC Safety Phrase

S 26 28 36/37/39 45 61

UN (DOT)

2671

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Weakness, dizziness, disorientation, hyperexcitibility, tremors, periorbital paresthesias and tonic-clonic seizures may be noted.

Poison Class

2

Fire Fighting Measures

Flash Point

164

Autoignition

640

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Containers may explode in the heat of a fire. Combustible solid. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Fire Potential

Some of these materials may burn but do not ignite readily.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity

Disposal Code

9

Incompatibilities

Oxidizing agents, strong acids, acid chlorides, acid anhydrides

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2671

Hazard Class

6.1

Packing Group

II

HS Code

2933 39 99