Product Identification

Product Name

Thiocarbamide

Synonyms

2-Thiourea
Isothiourea
Pseudothiourea
Thiocarbamide

CAS

62-56-6

Formula

CH4N2S

Molecular Weight

76.12

EINECS

200-543-5

RTECS

YU2800000

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Primary Irritant

Merck

12,9505

Beilstein/Gmelin

605327

Beilstein Reference

4-03-00-00342

EC Index Number

612-082-00-0

EC Class

Carcinogenic Category 3; Toxic for reproduction Category 3; Harmful; Dangerous for the Environment

Physical and Chemical Properties

Appearance

White, lustrous crystals.

Solubility in water

Soluble

Melting Point

174 - 177

Vapor Pressure

0.002 (100 C)

Density

1.435 g/cm3 (20 C)

pKa/pKb

-1.0(at 25℃) (pKa)

Partition Coefficient

-1.08

Heat Of Vaporization

60.0 kJ/mol

Heat Of Combustion

-1489 kJ/mol

Usage

Photographic fixing agent and to remove stains from negatives, manufacture of resins, vulcanization accelerator, a reagent for bismuth, selenite ions.

Vapor Density

2.6

Refractive Index

1.637 (30 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Induce vomiting by giving one teaspoon of Syrup of Ipecac. Call a poison control center.

Inhalation

Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Skin

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Do not ingest or inhale. Discard contaminated shoes.

Hazards Identification

Inhalation

May cause respiratory tract irritation.

Skin

Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May cause skin eruptions.

Eyes

Causes eye irritation.

Ingestion

Harmful if swallowed. May cause allergic reaction characterized by a rash. May cause severe irritation of the digestive tract. May cause anemia, leukopenia, and thrombocytopenia. May cause bone marrow depression.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 22 40 51/53 63

EC Safety Phrase

S 36/37 61

UN (DOT)

2877

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Chronic ingestion may cause liver damage. May cause cancer according to animal studies. May cause reproductive and fetal effects. Prolonged or repeated exposure may cause thyroid damage. Laboratory experiments have resulted in mutagenic effects.

Poison Class

3

Fire Fighting Measures

Autoignition

440

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing media: Substance is nonflammable; use agent most appropriate to extinguish surrounding fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

Slightly flammable.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Incompatibilities

Oxidizing agents, strong acids, strong bases, acrolein, nitric acid, hydrogen peroxides, acrylaldehyde.

Stability

Stable under normal temperatures and pressures. Polymerization may occur upon heating.

Decomposition

Nitrogen oxides, carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Combustion Products

May contain highly toxic fumes of NOx and SOx.

Transport Information

UN Number

2877

Hazard Class

6.1

Packing Group

III

HS Code

2930 90 70