VICRIVIROC MALEATE

Product Name: VICRIVIROC MALEATE
CAS No.: 599179-03-0
Chemical Name: VICRIVIROC MALEATE
Synonyms: SCH-D;CS-1868;Unii-ep3qg127N9;SCH-D (maleate);SCH-417690; SCH-D;VICRIVIROC MALEATE;SCH-417690 (maleate);vicriviroc Maleate salt;VICRIVIROC MALEATE: SCH-D;Vicriviroc Malate(maleate)
CBNumber: CB01011681
Molecular Formula: C32H42F3N5O6
Formula Weight: 649.7009896
MOL File: 599179-03-0.mol

More

Less

VICRIVIROC MALEATE Property

storage temp.: Store at -20°C
solubility: DMSO : 50 mg/mL (76.96 mM; Need ultrasonic)H2O : 25 mg/mL (38.48 mM; Need ultrasonic and warming)
form: Powder
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2768
Product name: Vicriviroc Maleate
Purity: ≥98% (HPLC)
Packaging: 1MG
Price: $94.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2768
Product name: Vicriviroc Maleate
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $381
Updated: 2024/03/01

Cayman Chemical

Product number: 28453
Product name: Vicriviroc (maleate)
Packaging: 1mg
Price: $86
Updated: 2024/03/01

Cayman Chemical

Product number: 28453
Product name: Vicriviroc (maleate)
Packaging: 10mg
Price: $421
Updated: 2024/03/01

Cayman Chemical

Product number: 28453
Product name: Vicriviroc (maleate)
Packaging: 5mg
Price: $274
Updated: 2024/03/01

More

Less

VICRIVIROC MALEATE Chemical Properties,Usage,Production

Description

Vicriviroc is a chemokine (C-C motif) receptor 5 (CCR5) antagonist (K_i = 2.5 nM). It selectively inhibits CCR5 over M₁ and M₂ muscarinic acetylcholine receptors (K_is = >10,000 nM for both) and human-ether-a-go-go (hERG) potassium channels (IC₅₀ = 5.8 μM). Vicriviroc decreases chemotaxis induced by chemokine (C-C motif) ligand 3 (CCL3) in Ba/F3 cells expressing recombinant human CCR5 with an IC₅₀ value of 0.91 nM. It inhibits the replication of 30 R5-tropic HIV-1 clinical isolates in peripheral blood mononuclear cells (PBMCs; EC₅₀s = 0.04-1.4 nM) and reduces viral entry of seven drug-resistant strains of HIV-1 in U87 cells expressing CD4 and CCR5 (EC₅₀s = 8.7-32.9 nM).

Uses

Antiviral, CCR5 antagonist, treatment of autoimmune conditions.

VICRIVIROC MALEATE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

VICRIVIROC MALEATE Suppliers

China 40 India 1 United Kingdom 1 United States 15 Global 57

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 9387
Advantage: 52

Shanghai PharmaChem CO.,Ltd.

Tel: 13621878384
Fax: 13621878384
Email: wm_pharchem@163.com
Country: China
ProdList: 20
Advantage: 60

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 13901585132
Fax: +86-25-52131256
Email: 799750417@qq.com
Country: China
ProdList: 8878
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

HBCChem, Inc.

Tel: +1-510-219-6317
Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
ProdList: 10648
Advantage: 60

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

More

Less

View Lastest Price from VICRIVIROC MALEATE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Vicriviroc maleate 599179-03-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Vicriviroc maleate 599179-03-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

599179-03-0, VICRIVIROC MALEATERelated Search:

Dioctadecyl dimethyl ammonium chloride 2,6-Lutidine 2-Amino-4,6-dimethylpyrimidine Vicriviroc Malate (4,6-dimethylpyrimidin-5-yl)-[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluor omethyl)phenyl]ethyl]-3-methyl-piperazin-1-yl]-4-methyl-1-piperidyl]me thanone Vicriviroc (hydrochloride)

SCH-417690; SCH-D

CS-1868

Vicriviroc Malate(maleate)

Vicriviroc Maleate(SCH 417690)

(4,6-diMethylpyriMidin-5-yl)(4-((S)-4-((R)-2-Methoxy-1-(4-(trifluoroMethyl)phenyl)ethyl)-3-Methylpiperazin-1-yl)-4-Methylpiperidin-1-yl)Methanone fuMarate

vicriviroc Maleate salt

1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate VicrivirocMalate

Vicriviroc maleate 1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate

SCH-D

VICRIVIROC MALEATE

VICRIVIROC MALEATE: SCH-D

Unii-ep3qg127N9

1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate

(4,6-dimethylpyrimidin-5-yl)(4-((S)-4-((R)-2-methoxy-1-(4-(trifluoromethyl)phenyl)ethyl)-3-methylpiperazin-1-yl)-4-methylpiperidin-1-yl)methanone maleate

SCH-417690 (maleate)

SCH-D (maleate)

Vicriviroc maleate (SCH-417690 maleate）

Piperidine, 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-, (2Z)-2-butenedioate (1:1) (9CI, ACI)

SCH-D,CCR,Inhibitor,HIV,CC chemokine receptor,SCH417690,inhibit,Vicriviroc maleate,SCH-417690,Vicriviroc,Human immunodeficiency virus,SCH 417690

599179-03-0

C28H38F3N5O2C4H4O4

C4H4O4C28H38F3N5O2

C32H42F3N5O6