4,4'-Cyclohexylidenebisphenol
- Product Name
- 4,4'-Cyclohexylidenebisphenol
- CAS No.
- 843-55-0
- Chemical Name
- 4,4'-Cyclohexylidenebisphenol
- Synonyms
- BISPHENOL Z;1,1-BIS(4-HYDROXYPHENYL)CYCLOHEXANE;1,1-Bis(4-hydroxyphenyl)cyclohexane (Bisphenol Z);Ai3-16834;Ccris 4918;Einecs 212-677-1;ZERENEX ZX005270;Bisphenol Z Solution;Bisphenol Z (100μg/mL);Bisphenol A Impurity 43
- CBNumber
- CB0103479
- Molecular Formula
- C18H20O2
- Formula Weight
- 268.35
- MOL File
- 843-55-0.mol
4,4'-Cyclohexylidenebisphenol Property
- Melting point:
- 190-192 °C(lit.)
- Boiling point:
- 371.51°C (rough estimate)
- Density
- 1.0496 (rough estimate)
- refractive index
- 1.5490 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- Water Solubility
- Practically insoluble in water
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 9.91±0.30(Predicted)
- color
- White to Almost white
- InChI
- InChI=1S/C18H20O2/c19-16-8-4-14(5-9-16)18(12-2-1-3-13-18)15-6-10-17(20)11-7-15/h4-11,19-20H,1-3,12-13H2
- InChIKey
- SDDLEVPIDBLVHC-UHFFFAOYSA-N
- SMILES
- C1(C2=CC=C(O)C=C2)(C2=CC=C(O)C=C2)CCCCC1
- CAS DataBase Reference
- 843-55-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 450421
- Product name
- 4,4′-Cyclohexylidenebisphenol
- Purity
- 98%
- Packaging
- 25g
- Price
- $61.75
- Updated
- 2025/07/31
- Product number
- 77923
- Product name
- BisphenolZ
- Purity
- analytical standard
- Packaging
- 100mg
- Price
- $55.2
- Updated
- 2021/12/16
- Product number
- B1568
- Product name
- 1,1-Bis(4-hydroxyphenyl)cyclohexane
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $49
- Updated
- 2025/07/31
- Product number
- B1568
- Product name
- 1,1-Bis(4-hydroxyphenyl)cyclohexane
- Purity
- >98.0%(GC)
- Packaging
- 100g
- Price
- $139
- Updated
- 2025/07/31
- Product number
- B1568
- Product name
- 1,1-Bis(4-hydroxyphenyl)cyclohexane
- Purity
- >98.0%(GC)
- Packaging
- 500g
- Price
- $397
- Updated
- 2025/07/31
4,4'-Cyclohexylidenebisphenol Chemical Properties,Usage,Production
Chemical Properties
White Crystal
Uses
Bisphenol Z is one of the many derivatives of Bisphenol A (B519495) that can be used as HIF (hypoxia-inducible factor) inhibitors, antitumor agents, angiogenesis inhibitors, and antihypoxic agents.
Definition
ChEBI: Bisphenol Z is a diarylmethane.
Synthesis
In a 500 mL four-necked flask equipped with a PTFE stirrer, thermometer, reflux condenser and HCl gas introduction tube, 150.4 g (16 mol) of phenol, 39.2 g (0.4 mol) of cyclohexanone, 100 mL of toluene, and 624 g (008 mol) of 2-mercaptoethanol were added; and +dried HCl gas was passed through the flask at a uniform rate of 016 mol/h. The reaction was heated to 30 ??C and maintained for 7 h. Stopping stirring and heating, the slurry was filtered under pressure to obtain a pink filter cake. The reaction was heated in a water bath, raised to 30 ??C and kept for 7 h. Stirring and heating were stopped and the resulting slurry-like consistency was filtered under reduced pressure to give a pink filter cake. The filter cake was washed with deionized water at 100 ?? for 3~4 times until the pH was 7, and the crude product was dried to obtain 114.5 g. The crude product was dissolved in a round bottom flask heated with anhydrous ethanol, and then filtered under reduced pressure while it was hot to filter off the impurities insoluble in ethanol, the filtrate was cooled to room temperature, and then put into a refrigerator to cool down for crystallization, and recrystallized for 2~3 times, and the white crystals of 105.5 g were obtained with the yield of 98.4%.
4,4'-Cyclohexylidenebisphenol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4,4'-Cyclohexylidenebisphenol manufacturers
- Product
- 4,4'-Cyclohexylidenebisphenol 843-55-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-15
- Product
- 4,4'-Cyclohexylidenebisphenol 843-55-0
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-02-06
- Product
- 4,4'-Cyclohexylidenebisphenol 843-55-0
- Price
- US $2.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10000
- Release date
- 2024-08-08