ChemicalBook > CAS DataBase List > 4,6-DIFLUOROINDOLINE-2,3-DIONE

4,6-DIFLUOROINDOLINE-2,3-DIONE

Product Name
4,6-DIFLUOROINDOLINE-2,3-DIONE
CAS No.
126674-93-9
Chemical Name
4,6-DIFLUOROINDOLINE-2,3-DIONE
Synonyms
4,6-Difluoroisat;BUTTPARK 50\07-84;4,6-DIFLUOROISATIN;6-DIFLUOROINDOLINE-2;,6-DIFLUOROINDOLINE-2,3-DIONE;4,6-DIFLUOROINDOLINE-2,3-DIONE;4,6-Difluoro-2,3-dioxoindoline;4,6-DifluorOoindoline-2,3-DIONE;1H-Indole-2,3-dione, 4,6-difluoro-;4,6-difluoro-2,3-dihydro-1H-indole-2,3-dione
CBNumber
CB0103671
Molecular Formula
C8H3F2NO2
Formula Weight
183.11
MOL File
126674-93-9.mol
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4,6-DIFLUOROINDOLINE-2,3-DIONE Property

Density 
1.578
storage temp. 
Sealed in dry,Room Temperature
pka
7.65±0.20(Predicted)
Appearance
Light yellow to green yellow Solid
InChI
InChI=1S/C8H3F2NO2/c9-3-1-4(10)6-5(2-3)11-8(13)7(6)12/h1-2H,(H,11,12,13)
InChIKey
YIVXDNUTNIKQMY-UHFFFAOYSA-N
SMILES
N1C2=C(C(F)=CC(F)=C2)C(=O)C1=O
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

TRC
Product number
D450975
Product name
4,6-Difluoroisatin
Packaging
1g
Price
$75
Updated
2021/12/16
TRC
Product number
D450975
Product name
4,6-Difluoroisatin
Packaging
100mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD34228
Product name
4,6-Difluoroisatin
Packaging
5G
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD34228
Product name
4,6-Difluoroisatin
Packaging
10g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
S415
Product name
4,6-Difluoroisatin
Packaging
5g
Price
$81
Updated
2021/12/16
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4,6-DIFLUOROINDOLINE-2,3-DIONE Chemical Properties,Usage,Production

Synthesis

940054-61-5

126674-93-9

Stage 2: Synthesis of 4,6-difluoro-1H-indole-2,3-dione The product of stage 1, 2-hydroxyimino-N-(3,5-difluorophenyl)-acetamide (21.1 g, 105 mmol) was slowly added to concentrated sulfuric acid (115 ml) preheated to 50-60°C. After maintaining this temperature and stirring for 15 minutes, the reaction mixture was warmed up to 100°C and stirring was continued for 30 minutes. After completion of the reaction, the mixture was cooled to room temperature and slowly poured into ice (1.2 kg). The precipitated solid was collected by filtration, washed to neutrality with plenty of water and finally dried in a desiccator using phosphorus pentoxide as desiccant. The yellow solid product 4,6-difluoro-1H-indole-2,3-dione was obtained 18.4 g in 95% yield. 1H-NMR (DMSO-d6) data: δ 6.60 (1H, dd, J = 8.8 and 2.0 Hz); 6.84 (1H, dt, J = 9.8 and 2.0 Hz); 11.20 (1H, br s).

References

[1] Patent: US2008/293749, 2008, A1. Location in patent: Page/Page column 14

4,6-DIFLUOROINDOLINE-2,3-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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4,6-DIFLUOROINDOLINE-2,3-DIONE Suppliers

kemikalieimport
Tel
--
Fax
--
Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
47
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View Lastest Price from 4,6-DIFLUOROINDOLINE-2,3-DIONE manufacturers

Hangzhou Milon Pharmatech Co.,Ltd.
Product
4,6-Difluoroindoline-2,3-Dione 126674-93-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
97.0%min;99.0%min
Supply Ability
MAKE TO ORDER
Release date
2025-12-01
Hefei Lbao Physical & Chemical Science Co.,Ltd
Product
4,6-Difluoroisatin 126674-93-9
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
Customise
Release date
2025-11-26
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
4,6-Difluoro-1H-indole-2,3-dione 126674-93-9
Price
US $2.20-8.80/kg
Min. Order
1kg
Purity
99%min
Supply Ability
100kg
Release date
2025-08-29

126674-93-9, 4,6-DIFLUOROINDOLINE-2,3-DIONERelated Search:


  • BUTTPARK 50\07-84
  • 4,6-DIFLUOROINDOLINE-2,3-DIONE
  • 4,6-DIFLUOROISATIN
  • 4,6-Difluoro isatin 4,6-Difluoro indole-2,3-dione
  • 4,6-Difluoro-2,3-dioxoindoline
  • 4,6-difluoro-2,3-dihydro-1H-indole-2,3-dione
  • 1H-Indole-2,3-dione, 4,6-difluoro-
  • 4,6-DIFLUOROINDOLINE-2,3-DIONE ISO 9001:2015 REACH
  • 6-DIFLUOROINDOLINE-2
  • 4,6-Difluoroisat
  • 4,6-DifluorOoindoline-2,3-DIONE
  • ,6-DIFLUOROINDOLINE-2,3-DIONE
  • 126674-93-9
  • Boronic Acid
  • Heterocyclic Compounds
  • Indoles and derivatives