7-Fluoroisatin

Product Name: 7-Fluoroisatin
CAS No.: 317-20-4
Chemical Name: 7-Fluoroisatin
Synonyms: 7-FLUOROINDOLINE-2,3-DIONE;1H-Indole-2,3-dione, 7-fluoro-;7-FL;7-FLUOROISATIN;7-Flouroisatin;7-Fluoroisation;7-FLUOROISATINE;7- fluorineisatin;BUTTPARK 24\07-37;7-Fluoroisatin>
CBNumber: CB0181767
Molecular Formula: C8H4FNO2
Formula Weight: 165.12
MOL File: 317-20-4.mol

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7-Fluoroisatin Property

Melting point:: 192-196°C
Density: 1.477±0.06 g/cm3(Predicted)
storage temp.: Store at room temperature
pka: 8.44±0.20(Predicted)
form: powder to crystal
color: Light yellow to Brown
Water Solubility: Sparingly Soluble in water (0.022 g/L)
InChI: InChI=1S/C8H4FNO2/c9-5-3-1-2-4-6(5)10-8(12)7(4)11/h1-3H,(H,10,11,12)
InChIKey: HGBGVEOXPHGSOS-UHFFFAOYSA-N
SMILES: N1C2=C(C=CC=C2F)C(=O)C1=O
CAS DataBase Reference: 317-20-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-43
Safety Statements: 37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29337900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 679119
Product name: 7-Fluoroisatin
Purity: 96%
Packaging: 5g
Price: $146
Updated: 2025/07/31

TCI Chemical

Product number: F0551
Product name: 7-Fluoroisatin
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $83
Updated: 2025/07/31

TCI Chemical

Product number: F0551
Product name: 7-Fluoroisatin
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $300
Updated: 2025/07/31

TRC

Product number: F592278
Product name: 7-Fluoroindoline-2,3-dione
Packaging: 1g
Price: $55
Updated: 2021/12/16

TRC

Product number: F592278
Product name: 7-Fluoroindoline-2,3-dione
Packaging: 2.5g
Price: $65
Updated: 2021/12/16

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7-Fluoroisatin Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

7-Fluoroisatin is used as the intermediate of cardiovascular, anti-inflammatory and bactericidal drugs.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 10, p. 23, 2004
Tetrahedron Letters, 35, p. 7303, 1994 DOI: 10.1016/0040-4039(94)85299-5

Synthesis

349-24-6

317-20-4

Step 2: 7-fluoroindoline-2,3-dione N-(2-fluorophenyl)-2-(hydroxyimino)acetamide (30 g, 164.84 mmol) was dissolved in concentrated sulfuric acid (100 mL), and the reaction was stirred at 80 °C for 2 hours. Upon completion of the reaction, the mixture was slowly poured into an ice-water mixture, and the precipitated brick-red solid was collected by filtration and dried to give 25 g of 7-fluorodihydroindole-2,3-dione in 90% yield. The product was analyzed by LCMS to confirm that the molecular ion peak was 166 (M + H)+.

References

[1] Patent: US2008/139558, 2008, A1. Location in patent: Page/Page column 55
[2] Journal of Heterocyclic Chemistry, 1990, vol. 27, # 7, p. 2151 - 2163
[3] Proceedings of the Royal Society of London, Series B: Biological Sciences, 1958, vol. 148, p. 481,488
[4] Journal of Medicinal Chemistry, 1992, vol. 35, # 11, p. 2085 - 2094
[5] European Journal of Medicinal Chemistry, 1994, vol. 29, # 10, p. 743 - 751

7-Fluoroisatin Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Fluoroisatin Suppliers

Americas 1 Canada 1 CHINA 251 Europe 3 Germany 8 India 13 Italy 1 Japan 3 Poland 1 Switzerland 3 Ukraine 2 United Kingdom 18 United States 43 Global 348

Tongchuang Pharma(Suzhou). Co., Ltd.

Tel: 0512-63263366 18912765016
Fax: 0512-6326 3366
Email: tongtf110@sina.com
Country: China
ProdList: 993
Advantage: 62

Weifang Yuda Pharmaceutical Technology Co., Ltd.

Tel: 17663603912
Fax: +86-536- 8637276
Email: 2710256076@qq.com
Country: China
ProdList: 196
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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
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TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
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Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
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Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
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Carbott PharmTech Inc.

Tel: 0535-6385396
Fax: +86 (535) 638-9971
Email: info@carbottpharm.com
Country: China
ProdList: 957
Advantage: 56

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View Lastest Price from 7-Fluoroisatin manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: 7-Fluoroisatin 317-20-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-08-19

Hebei Chuanghai Biotechnology Co., Ltd

Product: 7-Fluoroisatin 317-20-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-07

Shaanxi Dideu Medichem Co. Ltd

Product: 7-Fluoroisatin 317-20-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 20T
Release date: 2024-05-22

317-20-4, 7-FluoroisatinRelated Search:

7-Fluoro-6-Methyl Isatin 7-Fluoroisatin 7-Fluoro-5-Methyl Isatin 6-FLUOROISATIN 5-FLUOROISATIN 6-FLUOROINDOLE-3-CARBOXALDEHYDE 5-FLUOROINDOLE-3-CARBOXALDEHYDE 7-Fluoro-4-Methyl Isatin Isatin 7-Fluoroindole Indole 4-FLUOROINDOLE-3-CARBOXALDEHYDE 6-Chloro-7-fluoro-1H-indole-2,3-dione 6,7-DIFLUOROINDOLINE-2,3-DIONE 4,7-DIFLUOROISATIN 5-BROMO-7-FLUOROISATIN 5,7-DIFLUORO ISATIN 5,6,7-trifluoro-1H-indole-2,3-dione

7-fluoromethylisatin

7-fluoro-2,3-dihydro-1H-indole-2,3-dione

7-Fluoro-2,3-dihydro-1H-indol-2,3-dione

7-Fluoroindolin-2,3-dione, 7-Fluoro-1H-indole-2,3-dione

7- fluorineisatin

1H-Indole-2,3-dione, 7-fluoro-

7-Fluoroisation

Indole-2,3-dione, 7-fluoro-

7-fluoroindole-1h-2,3-dione

7-FLUOROINDOLE-2,3-DIONE

7-FLUOROINDOLINE-2,3-DIONE

7-FLUOROISATIN

7-FLUOROISATINE

7-FLUORO-1H-INDOLE-2,3-DIONE

BUTTPARK 24\07-37

5-(TRIFLUOROMETHYL) ISTATIN

7-Fluoro-2,3-indolinedione

7-FLUOROINDOLE-3-CARBOXALDEHYDE

7-FL

7-Fluoroisatin&gt

7-Flouroisatin

7-Fluoro-1H-indol-2,3-dione

317-20-4

5696-44-0

Indoles

Simple Indoles

intermediates

Indane/Indanone and Derivatives

Indoles

Simple Indoles