4,6-Dichloropyridine-3-acetonitrile
- Product Name
- 4,6-Dichloropyridine-3-acetonitrile
- CAS No.
- 199283-52-8
- Chemical Name
- 4,6-Dichloropyridine-3-acetonitrile
- Synonyms
- 3-Pyridineacetonitrile, 4,6-dichloro-;2-(4,6-Dichloro-3-pyridyl)acetonitrile;(4,6-Dichloro-3-Pyridinyl)Acetonitrile;2-(4,6-DICHLOROPYRIDIN-3-YL)ACETONITRILE
- CBNumber
- CB01074150
- Molecular Formula
- C7H4Cl2N2
- Formula Weight
- 187.03
- MOL File
- 199283-52-8.mol
4,6-Dichloropyridine-3-acetonitrile Property
- Boiling point:
- 315.3±37.0 °C(Predicted)
- Density
- 1.408±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -0.47±0.10(Predicted)
- Appearance
- White to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 4386CH
- Product name
- 2-(4,6-Dichloropyridin-3-yl)acetonitrile
- Packaging
- 1g
- Price
- $875
- Updated
- 2021/12/16
- Product number
- CD11170279
- Product name
- 2-(4,6-Dichloropyridin-3-yl)acetonitrile
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $230
- Updated
- 2021/12/16
- Product number
- CM251007
- Product name
- 2-(4,6-Dichloropyridin-3-yl)acetonitrile
- Purity
- 95%
- Packaging
- 1g
- Price
- $542
- Updated
- 2021/12/16
- Product number
- CD11170279
- Product name
- 2-(4,6-Dichloropyridin-3-yl)acetonitrile
- Purity
- 95+%
- Packaging
- 1g
- Price
- $574
- Updated
- 2021/12/16
- Product number
- UT00417
- Product name
- 2-(4,6-Dichloropyridin-3-yl)acetonitrile
- Purity
- 97%
- Packaging
- 1g
- Price
- $739.42
- Updated
- 2021/12/16
4,6-Dichloropyridine-3-acetonitrile Chemical Properties,Usage,Production
Synthesis
7677-24-9
1227606-01-0
199283-52-8
Step 2: 5-(bromomethyl)-2,4-dichloropyridine (0.500 g, 1.87 mmol) was dissolved in acetonitrile (5.0 mL). To this solution was added sodium hydroxide monohydrate (UOH-H2O, 0.0960 g, 2.24 mmol) followed by slow dropwise addition of trimethylcyanosilane (0.280 mL, 2.24 mmol). The reaction mixture was stirred continuously at room temperature for 2 hours. After completion of the reaction, the reaction solution was diluted with ethyl acetate. The diluted solution was washed twice with water. The organic phase was dried over anhydrous sodium sulfate, then the filtrate was filtered and concentrated to give a yellow oily crude product (394 mg). The crude product was purified by fast column chromatography (eluent: cyclohexane/ethyl acetate, 4:1) to afford the target product 2-(4,6-dichloropyridin-3-yl)acetonitrile (329 mg) in white solid form. The product was characterized by 1H-NMR (CDCl3): δ 8.5 (s, 1H), 7.47 (s, 1H), 3.82 (s, 2H).
References
[1] Patent: WO2013/64521, 2013, A1. Location in patent: Page/Page column 110
4,6-Dichloropyridine-3-acetonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
4,6-Dichloropyridine-3-acetonitrile Suppliers
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- info@synthonix.com
- Country
- United States
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