MOG
Description Background- Product Name
- MOG
- Chemical Name
- MOG
- Synonyms
- MOG;BTN6;BTNL11;NRCLP7;MOGIG2;Recombinant Human MOG Protein, His Tag
- CBNumber
- CB01114494
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- 255889
- Product name
- MOG
- Packaging
- 1mg
- Price
- $495
- Updated
- 2021/12/16
- Product number
- orb528073
- Product name
- MOG
- Packaging
- 10μg
- Price
- $290.7
- Updated
- 2021/12/16
MOG Chemical Properties,Usage,Production
Description
Myelin Oligodendrocyte Glycoprotein is a single, non-glycosylated polypeptide chain containing 21 amino acids and having a molecular mass of 2581 Dalton, the molecular formula: C118H177N35O29S.
Background
MOG is a transmembrane protein expressed on the surface of oligodendrocyte cell and on the outermost surface of myelin sheaths. MOG comprises about 0.1% of total CNS myelin protein. The MOG gene is a member of the immunoglobulin gene superfamily and is found within the MHC. The MOG gene is found on chromosome 6p21.3-p22. Myelin Oligodendrocyte Glycoprotein is a glycoprotein thought to be significant in the process of myelinization of nerves in the central nervous system (CNS). MOG peptide (35-55) is highly encephalitogenic and can induce strong T and B cell responses. A single injection of this peptide produces a relapsing- remitting neurologic disease with extensive plaque-like demyelination. Because of the clinical, histophathologic, and immunologic similarities with multiple sclerosis (MS), the MOG induced demyelinating encephalomyelitis may serve as a model for investigating MS.
MOG Preparation Products And Raw materials
Raw materials
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