ChemicalBook > CAS DataBase List > (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane

Product Name
(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane
CAS No.
156474-22-5
Chemical Name
(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane
Synonyms
Atazanavir Impurity 32;(2S,3R)-1,2-Epoxy-(Boc amino)-4-phenylbutane;(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane;threo-N-(Tert-Butoxy)Carbonyl D-phenylalanine epoxide;tert-butyl ((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbaMate;(2S,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane;tert-butyl [(2R,3S)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate;(2S,3R)-3-(tert-ButoxycarbonylaMino)-1,2-epoxy-4-phenylbutane;tert-butyl N-[(1R)-1-[(2S)-oxiran-2-yl]-2-phenylethyl]carbamate;2-Methyl-2-propanyl {(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl}carba mate
CBNumber
CB01122327
Molecular Formula
C15H21NO3
Formula Weight
263.33
MOL File
156474-22-5.mol
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(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Property

Melting point:
90-95°C
Boiling point:
398.8±25.0 °C(Predicted)
Density 
1.118±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform, DMSO, Methanol
form 
Solid
pka
12.19±0.46(Predicted)
color 
White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0068781
Product name
(2S,3R)-3-(N-BOC-AMINO)-1-OXIRANE-4-PHENYLBUTANE
Purity
95.00%
Packaging
5MG
Price
$502.81
Updated
2021/12/16
JR MediChem
Product number
JR6-L2705
Product name
Carbamicacid,N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-,1,1-dimethylethylester
Purity
96%
Packaging
1g
Price
$980
Updated
2021/12/16
JR MediChem
Product number
JR6-L2705
Product name
Carbamicacid,N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-,1,1-dimethylethylester
Purity
96%
Packaging
5g
Price
$2480
Updated
2021/12/16
JR MediChem
Product number
JR6-L2705
Product name
Carbamicacid,N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-,1,1-dimethylethylester
Purity
96%
Packaging
25g
Price
$7980
Updated
2021/12/16
Ambeed
Product number
A789622
Product name
tert-Butyl((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbamate
Purity
97%
Packaging
1g
Price
$43
Updated
2021/12/16
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(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Chemical Properties,Usage,Production

Uses

(2S,3R)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane is an intermediate in the synthesis of Atazanavir (A790050), a novel azapeptide HIV protease inhibitor used as an antiviral agent.

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Preparation Products And Raw materials

Raw materials

Preparation Products

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(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Suppliers

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156474-22-5, (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutaneRelated Search:

(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane Atazanavir Impurity 6 Des(benzylpyridyl) Atazanavir Des-N-(methoxycarbonyl)-L-tert-leucine Atazanavir Trihydrochloride Atazanavir Impurity 8 (3R,8S,9S,12R)-Atazanavir threo-N-(Tert-Butoxy)Carbonyl L-homophenylalanine epoxide (S)-1-(TERT-BUTOXYCARBONYL)-2,3-OXIRANYLMETHYLAMINE 4-(2-Pyridinyl)benzaldehyde (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane Atazanavir Impurity Atazanavir S,S,R,S-Diastereomer (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane TERT-BUTYL N-(2-OXIRANYLMETHYL)CARBAMATE Atazanavir tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir Atazanavir IMpurity 4 Atazanavir Sulfate

  • (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane
  • (2S,3R)-3-(tert-ButoxycarbonylaMino)-1,2-epoxy-4-phenylbutane
  • tert-butyl ((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbaMate
  • 2-Methyl-2-propanyl {(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl}carba mate
  • threo-N-(Tert-Butoxy)Carbonyl D-phenylalanine epoxide
  • (2S,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane
  • Atazanavir Impurity 32
  • tert-butyl N-[(1R)-1-[(2S)-oxiran-2-yl]-2-phenylethyl]carbamate
  • tert-butyl [(2R,3S)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate
  • (2S,3R)-1,2-Epoxy-(Boc amino)-4-phenylbutane
  • Carbamic acid, N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-, 1,1-dimethylethyl ester
  • Atazanavir Intermediate Enantiomer ((2S,3R)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane)
  • 156474-22-5
  • Aromatics, Chiral Reagents, Heterocycles