ChemicalBook > CAS DataBase List > (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane

Product Name
(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane
CAS No.
156474-22-5
Chemical Name
(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane
Synonyms
Atazanavir Impurity 32;(2S,3R)-1,2-Epoxy-(Boc amino)-4-phenylbutane;(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane;threo-N-(Tert-Butoxy)Carbonyl D-phenylalanine epoxide;tert-butyl ((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbaMate;(2S,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane;tert-butyl [(2R,3S)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate;(2S,3R)-3-(tert-ButoxycarbonylaMino)-1,2-epoxy-4-phenylbutane;tert-butyl N-[(1R)-1-[(2S)-oxiran-2-yl]-2-phenylethyl]carbamate;2-Methyl-2-propanyl {(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl}carba mate
CBNumber
CB01122327
Molecular Formula
C15H21NO3
Formula Weight
263.33
MOL File
156474-22-5.mol
More
Less

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Property

Melting point:
90-95°C
Boiling point:
398.8±25.0 °C(Predicted)
Density 
1.118±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform, DMSO, Methanol
form 
Solid
pka
12.19±0.46(Predicted)
color 
White
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0068781
Product name
(2S,3R)-3-(N-BOC-AMINO)-1-OXIRANE-4-PHENYLBUTANE
Purity
95.00%
Packaging
5MG
Price
$502.81
Updated
2021/12/16
JR MediChem
Product number
JR6-L2705
Product name
Carbamicacid,N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-,1,1-dimethylethylester
Purity
96%
Packaging
1g
Price
$980
Updated
2021/12/16
JR MediChem
Product number
JR6-L2705
Product name
Carbamicacid,N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-,1,1-dimethylethylester
Purity
96%
Packaging
5g
Price
$2480
Updated
2021/12/16
JR MediChem
Product number
JR6-L2705
Product name
Carbamicacid,N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-,1,1-dimethylethylester
Purity
96%
Packaging
25g
Price
$7980
Updated
2021/12/16
Ambeed
Product number
A789622
Product name
tert-Butyl((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbamate
Purity
97%
Packaging
1g
Price
$43
Updated
2021/12/16
More
Less

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Chemical Properties,Usage,Production

Uses

(2S,3R)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane is an intermediate in the synthesis of Atazanavir (A790050), a novel azapeptide HIV protease inhibitor used as an antiviral agent.

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Suppliers

China 47 India 4 Ireland 1 Japan 1 United Kingdom 1 United States 5 Global 59
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8073
Advantage
58
Shanghai Chainpharm Bio-medical Technology Co., Ltd.
Tel
+86-021-61727342 13611721451
Fax
021-61294107
Email
chainpharm@163.com
Country
China
ProdList
947
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17993
Advantage
56
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6740
Advantage
55
Shanghai GL Peptide Ltd.
Tel
+86-21-61263310; 13764994101 13764994101
Fax
021-61263399
Email
fisherwang@glschina.com
Country
China
ProdList
8465
Advantage
55
Wuxi Asia Peptide Biotechnology Limited Company
Tel
0510-83583050 13771062561
Fax
0510-83583039
Email
willsun@peptide-search.com
Country
China
ProdList
6716
Advantage
58
Nanjing Peptide Biotech Ltd.
Tel
025-025-58361106-805-805 13082558573
Fax
025-58361106-806
Email
liugang@njpeptide.com
Country
China
ProdList
9962
Advantage
55
Aikon International Limited
Tel
025-66113011 18112977050
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
16028
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
56039
Advantage
58
Kanghua (Shanghai) New Drug Development Co., Ltd.
Tel
021-61263370 18901917034
Email
xingli@glbiochem.com
Country
China
ProdList
5637
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19105
Advantage
58
Shanghai Jifeng Biotechnology Co., Ltd.
Tel
021-61263377 15023907684
Fax
021-61263399
Email
15800684150@163.com
Country
China
ProdList
8131
Advantage
58
Hangzhou Proserre Chemical Co.,Ltd.
Tel
+86-571-86088112
Email
info@proserre.com
Country
China
ProdList
1077
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19915
Advantage
58
Guangzhou Dreampharm Biotechnology Co., Ltd.
Tel
020-36607679 17825480238
Fax
QQ 3008233717
Email
3008233717@qq.com
Country
China
ProdList
9843
Advantage
12
Shanghai Anhua Biotechnology Co., Ltd.
Tel
021-61263375 18168859245
Country
China
ProdList
5958
Advantage
58
Jinan blalong chemical co. LTD
Tel
2710913286@.com
Email
1513643261@qq.com
Country
China
ProdList
14253
Advantage
58
Wuxi maimo topp biotechnology co., LTD
Tel
15861600115
Email
lisa-li@mimotopes.cn
Country
China
ProdList
5850
Advantage
58
Jiangsu Hongmin Pharmaceutical Co., Ltd.
Tel
18221292452
Email
fannieliu@glschina.com
Country
China
ProdList
6799
Advantage
58
Jiangsu Jitai Peptide Technology Co., Ltd.
Tel
18801776727
Email
matthew.meng@gtaipeptide.com
Country
China
ProdList
2010
Advantage
58
Jiangsu Shengkang Meixiang Technology Co., Ltd.
Tel
18217475093
Email
1615396342@qq.com
Country
China
ProdList
4309
Advantage
58
Gill polypeptide biopharmaceutical (dalian) co., LTD
Tel
021-61263455 13167021076
Email
amy@glschina.com
Country
China
ProdList
8313
Advantage
58
Neostar United (Changzhou) Industrial Co., Ltd.
Tel
+86-519-519-85557386
Fax
+0086-519-85557389
Email
marketing1@neostarunited.com
Country
China
ProdList
12917
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
4008210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
55023
Advantage
58
Meng Cheng Technology (Shanghai) Co., LTD
Tel
400-820-6829
Email
sales@mitachieve.com
Country
China
ProdList
8864
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44843
Advantage
58
Guangzhou Juntang Technology Co., Ltd
Tel
020-36607679 13502246435
Email
sales@dmstandards.com
Country
China
ProdList
10951
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
29778
Advantage
58
Changzhou Xianglong Pharmaceutical Technology Co., LTD
Tel
0519-88910898 18661161657
Email
yaoxiangqiu2021@163.com
Country
China
ProdList
10066
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Email
product02@bidepharm.com
Country
China
ProdList
63720
Advantage
58
Hubei Hannuo Pharmaceutical Technology Co., Ltd
Tel
18662190603
Email
437347250@qq.com
Country
China
ProdList
7330
Advantage
58
Shenzhen Roark Pharma-Tec Co., Ltd.
Tel
13128912434
Email
2880126944@qq.com
Country
China
ProdList
2579
Advantage
58
Scinova Biotech(Guangzhou) Co., Ltd.
Tel
13268215580
Email
scinova_sales@163.com
Country
China
ProdList
7026
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169109
Email
market03@meryer.com
Country
China
ProdList
27996
Advantage
58
ShenZhen Trendseen Biological Technology Co.,Ltd.
Tel
13417589054 13417589054
Email
trendseenbio@gmail.com
Country
China
ProdList
8941
Advantage
58
Shanghai Zerui Biotechnology Co., Ltd.
Tel
021-54580889 18321124657
Fax
021-54580889
Email
731997554@qq.com
Country
China
ProdList
10614
Advantage
58
Nantong Hanfang Biotechnology Co. , Ltd.
Tel
3674309880
Email
hanfangpharma@126.com
Country
China
ProdList
30968
Advantage
58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd
Tel
17316404525
Email
209533805@qq.com
Country
China
ProdList
9661
Advantage
58
Suzhou ARTK Medchem Co., Ltd.
Tel
+8618168183658
Email
sales1@artkmedchem.com
Country
China
ProdList
39009
Advantage
58
LEAPCHEM CO., LTD.
Tel
+86-852-30606658
Email
market18@leapchem.com
Country
China
ProdList
43348
Advantage
58
ShenZhen Trendseen Biological Technology Co.,Ltd.
Tel
13417589054
Email
trendseenbio@gmail.com
Country
China
ProdList
11681
Advantage
58
China National Standard Pharmaceutical Corporation Limited
Tel
+8615391658522
Email
overseasales@yongstandards.com
Country
China
ProdList
11927
Advantage
58
Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel
+86-057181025280; +8617767106207
Fax
0571-85806285
Email
sales@molcore.com
Country
China
ProdList
49739
Advantage
58
Shanghai Yubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
344843571@qq.com
Country
CHINA
ProdList
6322
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6846
Advantage
58

156474-22-5, (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutaneRelated Search:

(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane Atazanavir Impurity 6 Des(benzylpyridyl) Atazanavir Des-N-(methoxycarbonyl)-L-tert-leucine Atazanavir Trihydrochloride Atazanavir Impurity 8 (3R,8S,9S,12R)-Atazanavir threo-N-(Tert-Butoxy)Carbonyl L-homophenylalanine epoxide (S)-1-(TERT-BUTOXYCARBONYL)-2,3-OXIRANYLMETHYLAMINE 4-(2-Pyridinyl)benzaldehyde (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane Atazanavir Impurity Atazanavir S,S,R,S-Diastereomer (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane TERT-BUTYL N-(2-OXIRANYLMETHYL)CARBAMATE Atazanavir tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir Atazanavir IMpurity 4 Atazanavir Sulfate

  • (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane
  • (2S,3R)-3-(tert-ButoxycarbonylaMino)-1,2-epoxy-4-phenylbutane
  • tert-butyl ((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbaMate
  • 2-Methyl-2-propanyl {(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl}carba mate
  • threo-N-(Tert-Butoxy)Carbonyl D-phenylalanine epoxide
  • (2S,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane
  • Atazanavir Impurity 32
  • tert-butyl N-[(1R)-1-[(2S)-oxiran-2-yl]-2-phenylethyl]carbamate
  • tert-butyl [(2R,3S)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate
  • (2S,3R)-1,2-Epoxy-(Boc amino)-4-phenylbutane
  • Carbamic acid, N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-, 1,1-dimethylethyl ester
  • Atazanavir Intermediate Enantiomer ((2S,3R)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane)
  • 156474-22-5
  • Aromatics, Chiral Reagents, Heterocycles