ChemicalBook > CAS DataBase List > (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane

Product Name
(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane
CAS No.
156474-22-5
Chemical Name
(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane
Synonyms
Atazanavir Impurity 32;(2S,3R)-1,2-Epoxy-(Boc amino)-4-phenylbutane;(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane;threo-N-(Tert-Butoxy)Carbonyl D-phenylalanine epoxide;tert-butyl ((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbaMate;(2S,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane;tert-butyl [(2R,3S)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate;(2S,3R)-3-(tert-ButoxycarbonylaMino)-1,2-epoxy-4-phenylbutane;tert-butyl N-[(1R)-1-[(2S)-oxiran-2-yl]-2-phenylethyl]carbamate;2-Methyl-2-propanyl {(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl}carba mate
CBNumber
CB01122327
Molecular Formula
C15H21NO3
Formula Weight
263.33
MOL File
156474-22-5.mol
More
Less

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Property

Melting point:
90-95°C
Boiling point:
398.8±25.0 °C(Predicted)
Density 
1.118±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform, DMSO, Methanol
form 
Solid
pka
12.19±0.46(Predicted)
color 
White
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0068781
Product name
(2S,3R)-3-(N-BOC-AMINO)-1-OXIRANE-4-PHENYLBUTANE
Purity
95.00%
Packaging
5MG
Price
$502.81
Updated
2021/12/16
Ambeed
Product number
A789622
Product name
tert-Butyl((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbamate
Purity
97%
Packaging
1g
Price
$43
Updated
2021/12/16
Ambeed
Product number
A789622
Product name
tert-Butyl((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbamate
Purity
97%
Packaging
25g
Price
$468
Updated
2021/12/16
JR MediChem
Product number
JR6-L2705
Product name
Carbamicacid,N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-,1,1-dimethylethylester
Purity
96%
Packaging
1g
Price
$980
Updated
2021/12/16
JR MediChem
Product number
JR6-L2705
Product name
Carbamicacid,N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-,1,1-dimethylethylester
Purity
96%
Packaging
5g
Price
$2480
Updated
2021/12/16
More
Less

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Chemical Properties,Usage,Production

Uses

(2S,3R)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane is an intermediate in the synthesis of Atazanavir (A790050), a novel azapeptide HIV protease inhibitor used as an antiviral agent.

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Suppliers

China 49 India 3 Ireland 1 Japan 1 United Kingdom 1 United States 5 Global 60
TopChem Laboratories Limited
Tel
--
Fax
--
Email
sales@topchem.ie
Country
Ireland
ProdList
97
Advantage
46

156474-22-5, (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutaneRelated Search:

(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane Atazanavir Impurity 6 Des(benzylpyridyl) Atazanavir Des-N-(methoxycarbonyl)-L-tert-leucine Atazanavir Trihydrochloride Atazanavir Impurity 8 (3R,8S,9S,12R)-Atazanavir threo-N-(Tert-Butoxy)Carbonyl L-homophenylalanine epoxide (S)-1-(TERT-BUTOXYCARBONYL)-2,3-OXIRANYLMETHYLAMINE 4-(2-Pyridinyl)benzaldehyde (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane Atazanavir Impurity Atazanavir S,S,R,S-Diastereomer (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane TERT-BUTYL N-(2-OXIRANYLMETHYL)CARBAMATE Atazanavir tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir Atazanavir IMpurity 4 Atazanavir Sulfate

  • (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane
  • (2S,3R)-3-(tert-ButoxycarbonylaMino)-1,2-epoxy-4-phenylbutane
  • tert-butyl ((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbaMate
  • 2-Methyl-2-propanyl {(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl}carba mate
  • threo-N-(Tert-Butoxy)Carbonyl D-phenylalanine epoxide
  • (2S,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane
  • Atazanavir Impurity 32
  • tert-butyl N-[(1R)-1-[(2S)-oxiran-2-yl]-2-phenylethyl]carbamate
  • tert-butyl [(2R,3S)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate
  • (2S,3R)-1,2-Epoxy-(Boc amino)-4-phenylbutane
  • Carbamic acid, N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-, 1,1-dimethylethyl ester
  • Atazanavir Intermediate Enantiomer ((2S,3R)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane)
  • 156474-22-5
  • Aromatics, Chiral Reagents, Heterocycles