(-)-ANABASINE
- Product Name
- (-)-ANABASINE
- CAS No.
- 494-52-0
- Chemical Name
- (-)-ANABASINE
- Synonyms
- Anabasin;Anabazin;ANOBASINE;ANABASINE;Neonikoti;Neonikotin;NEONICOTINE;L-ANABASINE;(-)-anabasin;(-)-ANABASINE
- CBNumber
- CB0119964
- Molecular Formula
- C10H14N2
- Formula Weight
- 162.23
- MOL File
- 494-52-0.mol
(-)-ANABASINE Property
- Melting point:
- 9°C
- Boiling point:
- 270-272°C
- alpha
- D20 -83.1°
- Density
- 1,0455 g/cm3
- refractive index
- 1.5430
- Flash point:
- 93°C
- storage temp.
- 2-8°C
- solubility
- DMSO : 100 mg/mL (616.41 mM)
- pka
- 8.98±0.10(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
- Merck
- 14,619
- BRN
- 82637
- CAS DataBase Reference
- 494-52-0(CAS DataBase Reference)
- NIST Chemistry Reference
- Pyridine, 3-(2-piperidinyl)-, (S)-(494-52-0)
- EPA Substance Registry System
- Anabasine (494-52-0)
Safety
- Hazard Codes
- T
- Risk Statements
- 27/28-51/53-23/24/25
- Safety Statements
- 28-36/37-45-61-36/37/39-28A
- RIDADR
- 3140
- RTECS
- BV4375000
- HazardClass
- 6.1
- PackingGroup
- I
- HS Code
- 29333990
- Hazardous Substances Data
- 494-52-0(Hazardous Substances Data)
- Toxicity
- LDLo orl-dog: 50 mg/kg JPETAB 48,95,33
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
H310Fatal in contact with skin
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P262Do not get in eyes, on skin, or on clothing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P350IF ON SKIN: Gently wash with plenty of soap and water.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P330Rinse mouth.
P361Remove/Take off immediately all contaminated clothing.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A637170
- Product name
- (S)-Anabasine,>98%ee
- Packaging
- 100mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- A637170
- Product name
- (S)-Anabasine,>98%ee
- Packaging
- 500mg
- Price
- $1455
- Updated
- 2021/12/16
- Product number
- HBL0000006
- Product name
- (-)-ANABASINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1593.9
- Updated
- 2021/12/16
- Product number
- AS7078-A
- Product name
- (S)-3-(Piperidin-2-yl)pyridine
- Purity
- 95+% ee
- Packaging
- 5G
- Price
- $2356
- Updated
- 2021/12/16
- Product number
- FA17898
- Product name
- (S)-Anabasine
- Packaging
- 500mg
- Price
- $675
- Updated
- 2021/12/16
(-)-ANABASINE Chemical Properties,Usage,Production
Chemical Properties
Pale Yellow Oil
Uses
Anabasine occurs in the tobacco speciesNicotiana glauca, Anabasis aphylla L.,Chenopodiaceae, and Solanaceae. It is usedas an insecticide and as a metal anticorrosiveagent.
Uses
(S)-ANABASINE is used as a kind of Nicotinic receptor agonist.
Definition
ChEBI: The (S)-enantiomer of anabasine.
Health Hazard
The acute toxic symptoms include increasedsalivation, confusion, disturbed vision, photophobia,nausea, vomiting, diarrhea, respiratorydistress, and convulsions. It causesrespiratory muscle stimulation similar to thatcaused by lobeline. An oral lethal dose indogs is 50 mg/kg. A subcutaneous lethaldose in guinea pigs is 10 mg/kg.
Biological Activity
Anabasine ((S)-Anabasine) is an alkaloid, a component of tobacco. Anabasine is a botanical insecticide that acts as a pan-agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization in TE671 cells endogenously expressing human myogenic nAChRs (EC50=0.7 μM).
Safety Profile
Poison by ingestion,subcutaneous, and intravenous routes. Moderately toxicby skin contact. An experimental teratogen. Insecticide.Acute and subacute toxicity: increased salivation, vertigo,confusion, disturbed vision and hearing, photophobia,cold ext
in vivo
Anabasine significantly reverses the impairment at the 0.2 mg/kg (p<0.05) and 2 mg/kg doses (p<0.025). Anabasine does not have any significant effects on response latency when administered alone. The 0.06 mg/kg Anabasine dose, in fact, significantly (p<0.05) exacerbates the dizocilpine-induced impairment. None of these Anabasine doses affects choice accuracy on their own. Individual dose comparisons show that the 0.06 mg/kg Anabasine dose plus dizocilpine (6.7±2.6) causes a significant (p<0.05) increase in non-response trials compare with dizocilpine alone (2.1±0.8).
(-)-ANABASINE Preparation Products And Raw materials
Raw materials
Preparation Products
(-)-ANABASINE Suppliers
- Tel
- --
- Fax
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- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
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- sales@carbonesci.com
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- United Kingdom
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- Tel
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- sales@etascientific.com
- Country
- United Kingdom
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- Tel
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- sales@gs-chem.com
- Country
- United Kingdom
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- 6098
- Advantage
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- Tel
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- Fax
- --
- solutions@vwr.com
- Country
- United Kingdom
- ProdList
- 6548
- Advantage
- 82
View Lastest Price from (-)-ANABASINE manufacturers
- Product
- (-)-ANABASINE 494-52-0
- Price
- US $30.00-17.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2024-07-15
- Product
- Anabasine 494-52-0
- Price
- US $1.00/KG
- Min. Order
- 0.5KG
- Purity
- >99%
- Supply Ability
- 20tons
- Release date
- 2021-07-28
- Product
- (-)-ANABASINE 494-52-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-10