ChemicalBook > CAS DataBase List > H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH

H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH

Product Name
H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
CAS No.
121204-87-3
Chemical Name
H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
Synonyms
4 ALA ET-1;[Ala1,3,11,15]ET-1;ASASSLMDKEAVYFAHLDIIW;[ALA1,3,11,15]-ENDOTHELIN;[ALA1,3,11,15]ENDOTHELIN-I;(ALA1,3,11,15)-ENDOTHELIN-1;endothelin 1, Ala(1,3,11,15)-;[Ala1,3,11,15]-Endothelin (53-63);[ALA1,3,11,16]-ENDOTHELIN 1, HUMAN;[ALA1,3,11,15] ENDOTHELIN-1, HUMAN
CBNumber
CB0121062
Molecular Formula
C109H163N25O32S
Formula Weight
2367.67
MOL File
121204-87-3.mol
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H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH Property

Boiling point:
2391.5±65.0 °C(Predicted)
Density 
1.319±0.06 g/cm3(Predicted)
storage temp. 
-20°C
form 
Solid
Water Solubility 
Soluble to 1 mg/ml in water
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P284Wear respiratory protection.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E6877
Product name
[Ala1,3,11,15]-Endothelin 1
Packaging
0.5mg
Price
$457
Updated
2024/03/01
Alfa Aesar
Product number
J66511
Product name
[Ala<sup>1</sup><sup>,</sup><sup>3</sup><sup>,</sup><sup>1</sup><sup>1</sup><sup>,</sup><sup>1</sup><sup>5</sup>] Endothelin-1, human
Packaging
1mg
Price
$145
Updated
2021/12/16
Alfa Aesar
Product number
J66511
Product name
[Ala<sup>1</sup><sup>,</sup><sup>3</sup><sup>,</sup><sup>1</sup><sup>1</sup><sup>,</sup><sup>1</sup><sup>5</sup>] Endothelin-1, human
Packaging
0.5mg
Price
$91.5
Updated
2021/12/16
Usbiological
Product number
E3098-30M
Product name
Endothelin 1 [Ala1,3,11,15]
Packaging
1mg
Price
$531
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0000006
Product name
H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
Purity
95.00%
Packaging
0.5MG
Price
$613.31
Updated
2021/12/16
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H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH Chemical Properties,Usage,Production

Uses

[Ala1,3,11,15]-Endothelin 1 may be used to assess the effects of endothelin-1 and [Ala1,3,11,15]-endothelin 1 produced by ETA and ETB receptors, in the presence of BQ-123, in anaesthetized rat.

General Description

[Ala1,3,11,15]-Endothelin 1 is a linear endothelin (ET)-1 analogue, and acts as an ETB receptor agonist. ET-1 is a peptide that acts as both, a vasodilator and a vasoconstrictor. It is a ligand for ET receptor, which is of two types, ETA and ETB. ETB receptor is found in the vascular endothelial cells of cardiovascular tissues.

Biochem/physiol Actions

Selective agonist for ETB endothelin receptors.

H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH Suppliers

China 51 France 1 Japan 1 Switzerland 2 The Netherlands 1 United Kingdom 3 United States 10 USA 1 Global 70
Carbosynth
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United Kingdom
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MOLEKULA Ltd.
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kevinbanks@molekula.com
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Tocris Bioscience
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customerservice@tocris.co.uk
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121204-87-3, H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OHRelated Search:

AC-GLY-TRP-OH H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH Endothelin-1 (human, porcine) ENDOTHELIN-1 [ALA1,3,11,15] [3-(125I)TYR] (HUMAN) BQ-3020 H-ILE-TRP-OH ENDOTHELIN (16-21) ([125I]-TYR)-ENDOTHELIN-1 (HUMAN, BOVINE, DOG, MOUSE, PORCINE, RAT) H-VAL-TRP-OH H-GLY-GLY-TRP-OH

  • H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
  • ASASSLMDKEAVYFAHLDIIW
  • 4 ALA ET-1
  • [ALA1,3,11,15]-ENDOTHELIN
  • (ALA1,3,11,15)-ENDOTHELIN-1
  • [ALA1,3,11,15] ENDOTHELIN-1, HUMAN
  • [ALA1,3,11,15]ENDOTHELIN-I
  • [ALA1,3,11,16]-ENDOTHELIN 1, HUMAN
  • ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP
  • endothelin 1, Ala(1,3,11,15)-
  • [Ala1,3,11,15]ET-1
  • L-Ala-L-Ser-L-Ala-L-Ser-L-Ser-L-Leu-L-Met-L-Asp-L-Lys-L-Glu-L-Ala-L-Val-L-Tyr-L-Phe-L-Ala-L-His-L-Leu-L-Asp-L-Ile-L-Ile-L-Trp-OH
  • L-Ala-L-Ser-L-Ala-L-Ser-L-Ser-L-Leu-L-Met-L-αAsp-L-Lys-L-αGlu-L-Ala-L-Val-L-Tyr-L-Phe-L-Ala-L-His-L-Leu-L-αAsp-L-Ile-L-Ile-L-Trp-OH
  • ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP: ASASSLMDKEAVYFAHLDIIW
  • (Ala1·3·11·15)-Endothelin-1 trifluoroacetate salt H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH trifluoroacetate salt
  • L-Tryptophan, L-alanyl-L-seryl-L-alanyl-L-seryl-L-seryl-L-leucyl-L-methionyl-L-α-aspartyl-L-lysyl-L-α-glutamyl-L-alanyl-L-valyl-L-tyrosyl-L-phenylalanyl-L-alanyl-L-histidyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-isoleucyl-
  • H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH USP/EP/BP
  • [Ala1,3,11,15]-Endothelin (53-63)
  • (Ala?·?·??·??)-Endothelin-1 trifluoroacetate salt
  • (2S,5S,8S,11S,14S,17S,20S,23S,26S,29S,32S,35S,38S,41S)-17-((1H-imidazol-5-yl)methyl)-2-((1H-indol-3-yl)methyl)-41-((2S,5S,8S,11S,14S,17S,20S)-20-amino-8,11,17-tris(hydroxymethyl)-5-isobutyl-14-methyl-2-(2-(methylthio)ethyl)-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazahenicosanamido)-38-(4-aminobutyl)-23-benzyl-5,8-di((S)-sec-butyl)-35-(2-carboxyethyl)-11-(carboxymethyl)-26-(4-hydroxybenzyl)-14-isobutyl-29-isopropyl-20,32-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxo-3,6,9,12,15,18,2
  • 121204-87-3
  • C109H163O32N25S
  • C109H163N25O32S
  • Biochemicals and Reagents
  • Amino Acids and Peptides
  • Agonist
  • BioChemical
  • Endothelins
  • Peptides
  • Endothelin receptor
  • Agonists
  • Endothelins
  • Peptides for Cell Biology
  • peptide