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1-Ethyl-2-methylindole

Product Name
1-Ethyl-2-methylindole
CAS No.
40876-94-6
Chemical Name
1-Ethyl-2-methylindole
Synonyms
1-Ethyl-2-methylndole;1-ETHYL-2-METHYLINDOLE;N-ETHYL-2-METHYLINDOLE;1-ethyl-2-methyl-1H-indole;1H-Indole, 1-ethyl-2-methyl-
CBNumber
CB0123192
Molecular Formula
C11H13N
Formula Weight
159.23
MOL File
40876-94-6.mol
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1-Ethyl-2-methylindole Property

Boiling point:
266-267 °C (lit.)
Density 
1.02 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.587(lit.)
Flash point:
>230 °F
storage temp. 
Store at room temperature
form 
powder to crystal
color 
White to Light yellow
CAS DataBase Reference
40876-94-6
EPA Substance Registry System
1H-Indole, 1-ethyl-2-methyl- (40876-94-6)
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Safety

WGK Germany 
3
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
136603
Product name
1-Ethyl-2-methylindole
Purity
97%
Packaging
25g
Price
$210.9
Updated
2025/07/31
TCI Chemical
Product number
E1376
Product name
1-Ethyl-2-methylindole
Packaging
5G
Price
$47
Updated
2025/07/31
TCI Chemical
Product number
E1376
Product name
1-Ethyl-2-methylindole
Packaging
25G
Price
$229
Updated
2025/07/31
TRC
Product number
E937173
Product name
1-Ethyl-2-methylindole
Packaging
100mg
Price
$45
Updated
2021/12/16
Chem-Impex
Product number
43033
Product name
1-Ethyl-2-methylindole,≥98%(GC)
Purity
≥98%(GC)
Packaging
25G
Price
$269.25
Updated
2021/12/16
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1-Ethyl-2-methylindole Chemical Properties,Usage,Production

Uses

1-Ethyl-2-methylindole may be used in synthesis of hetrocyclic indole compounds.

Synthesis Reference(s)

Synthesis, p. 617, 1979 DOI: 10.1055/s-1979-28783

Synthesis

95-20-5

75-03-6

40876-94-6

Example 1 Synthesis of JWH4511-ethyl-2-methylindole: To a reaction vial containing 0.20 g (1.52 mmol) of 2-methylindole was added 6 mL of a DMSO-dissolved solution of 0.38 g (6.89 mmol) of KOH, followed by 0.24 mL (3.04 mmol) of ethyl iodide. The reaction mixture was stirred at room temperature for 12 hours. Upon completion of the reaction, the reaction was quenched by the addition of 15 mL of water and extracted with ethyl acetate (2 x 15 mL). The organic phases were combined, washed sequentially with water (10 mL) and brine (20 mL), dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by column chromatography (eluent: ethyl ether/petroleum ether=0.5:9.5) to afford 0.20 g (83% yield) of the target compound N-ethyl-2-methylindole as a red oil.

References

[1] Patent: WO2012/24670, 2012, A2. Location in patent: Page/Page column 43
[2] Synthesis, 1981, # 5, p. 389 - 390
[3] Organic Letters, 2017, vol. 19, # 17, p. 4680 - 4683

1-Ethyl-2-methylindole Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Ethyl-2-methylindole Suppliers

Heze Bona Medical Technology Co., LTD
Tel
18615487702
Email
614989876@qq.com
Country
China
ProdList
3000
Advantage
58
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Aemon Chemical
Tel
0086-755-86198205
Email
acinfo@aemonchem.com
Country
China
ProdList
1931
Advantage
57
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq:2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
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View Lastest Price from 1-Ethyl-2-methylindole manufacturers

Henan Xiangtong Chemical Co., Ltd.
Product
1-Ethyl-2-methylindole 40876-94-6
Price
US $11.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
100MT
Release date
2019-08-02
Career Henan Chemical Co
Product
1-Ethyl-2-methylindole 40876-94-6
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
100kg/week
Release date
2019-08-05

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