Description
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rhapontigenin

Description
Product Name
rhapontigenin
CAS No.
500-65-2
Chemical Name
rhapontigenin
Synonyms
Protigenin;rhapontigenin;3-benzenediol;Rhapontigenin-RM;Rhapontigenin >rhapontigenin USP/EP/BP;-5-(3-Hydroxy-4-methoxystyryl);COc2ccc(/C=C/c1cc(O)cc(O)c1)cc2O;(E)-4'-Methoxy-3,3',5-stilbenetriol;3,3',5-Trihydroxy-4'-methoxy-trans-stilbene
CBNumber
CB01309681
Molecular Formula
C15H14O4
Formula Weight
258.27
MOL File
500-65-2.mol
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rhapontigenin Property

Melting point:
189.0 to 193.0 °C
Boiling point:
503.6±38.0 °C(Predicted)
Density 
1.345±0.06 g/cm3(Predicted)
storage temp. 
4°C, protect from light
solubility 
≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
form 
powder to crystal
pka
9.17±0.10(Predicted)
color 
White to Light yellow
CAS DataBase Reference
500-65-2
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Safety

HS Code 
2914.50.3000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical
Product number
R0089
Product name
Rhapontigenin
Purity
>98.0%(GC)
Packaging
100mg
Price
$310
Updated
2024/03/01
Cayman Chemical
Product number
13293
Product name
Rhapontigenin
Purity
≥98%
Packaging
1mg
Price
$89
Updated
2024/03/01
Cayman Chemical
Product number
13293
Product name
Rhapontigenin
Purity
≥98%
Packaging
5mg
Price
$395
Updated
2024/03/01
Cayman Chemical
Product number
13293
Product name
Rhapontigenin
Purity
≥98%
Packaging
10mg
Price
$700
Updated
2024/03/01
Cayman Chemical
Product number
13293
Product name
Rhapontigenin
Purity
≥98%
Packaging
25mg
Price
$1528
Updated
2024/03/01
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rhapontigenin Chemical Properties,Usage,Production

Description

Rhapontigenin is a natural analog of resveratrol and an inhibitor of CYP1A1.

Description

Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. It is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50 = 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. At higher concentrations, rhapontigenin inhibits the proliferation of HepG2 and HL-60R cancer cell lines (IC50 = 48 μM).

Uses

Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. It is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50 = 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. At higher concentrations, rhapontigenin inhibits the proliferation of HepG2 and HL-60R cancer cell lines (IC50 = 48 μM).[Cayman Chemical]

Uses

Rhapontigenin is a natural analog of resveratrol and an inhibitor of CYP1A1.

Definition

ChEBI: Rhapontigenin is a stilbenoid.

References

[1]. chun yj, ryu sy, jeong tc, et al. mechanism-based inhibition of human cytochrome p450 1a1 by rhapontigenin. drug metab dispos. 2001 apr;29(4 pt 1):389-93.
[2]. roberti m1, pizzirani d, simoni d, et al. synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents. j med chem. 2003 jul 31;46(16):3546-54.
[3]. roupe ka1, helms gl, halls sc, et al. preparative enzymatic synthesis and hplc analysis of rhapontigenin: applications to metabolism, pharmacokinetics and anti-cancer studies. j pharm pharm sci. 2005 aug 22;8(3):374-86.

rhapontigenin Preparation Products And Raw materials

Raw materials

Preparation Products

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rhapontigenin Suppliers

China 160 India 2 Japan 1 United States 12 USA 1 Global 176
EMMX Biotechnology LLC
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Cayman Chemical Company
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View Lastest Price from rhapontigenin manufacturers

BINBO BIOLOGICAL CO.,LTD
Product
Rhapontigenin 500-65-2
Price
US $0.00/kg
Min. Order
1kg
Purity
>98%
Supply Ability
1000 kg
Release date
2024-04-25
PNP Biotech Co. Ltd
Product
Rhapontigenin 500-65-2
Price
US $0.00/kg
Min. Order
25kg
Purity
98%
Supply Ability
Inquiry
Release date
2022-10-25
Shanghai Standard Technology Co., Ltd.
Product
Rhapontigenin 500-65-2
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-03-26

500-65-2, rhapontigeninRelated Search:

RHAPONTIN 3,5-DIHYDROXY-4'-METHOXYSTILBENE 3-O-BETA-D-GLUCOSIDE chebulagic acid Hydroxytyrosol 10-Gingerol Hydroxytyrosol Acetate Chebulic Acid α-Naphthoflavone (E)-3-Hydroxy-4',5-dimethoxystilbene Acetyl-trans-resveratrol PICEATANNOL Oxyresveratrol 3'-Hydroxypterostilbene Vitexin isorhapontigenin Aloe emodin Emodin-3-methyl ether Emodin

  • 3-benzenediol
  • 5-[(1E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-1
  • 5-[(1E)-2-(3-HYDROXY-4-METHOXYPHENYL)ETHENYL]-1;3-BENZENEDIOL
  • 5-[2-(3-hydroxy-4-methoxyphenyl)ethenyl]benzene-1,3-diol
  • rhapontigenin
  • (E)-5-[2-(3-Hydroxy-4-methoxyphenyl)ethenyl]-1,3-benzenediol
  • 3,3',5-Trihydroxy-4'-methoxy-trans-stilbene trans-1-(3,5-Dihydroxyphenyl)-2-(3-hydroxy-4-methoxyphenyl)ethylene
  • (E)-4'-Methoxy-3,3',5-stilbenetriol
  • (E)-5-(3-Hydroxy-4-Methoxystyryl)benzene-1,3-diol
  • -5-(3-Hydroxy-4-methoxystyryl)
  • Rhapontigenin &gt
  • Protigenin
  • 1,3-Benzenediol,5-[(1E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-
  • 3,3',5-Trihydroxy-4'-methoxy-trans-stilbene
  • trans-1-(3,5-Dihydroxyphenyl)-2-(3-hydroxy-4-methoxyphenyl)ethylene
  • rhapontigenin USP/EP/BP
  • COc2ccc(/C=C/c1cc(O)cc(O)c1)cc2O
  • Rhapontigenin-RM
  • 500-65-2