10-Gingerol

Product Name: 10-Gingerol
CAS No.: 23513-15-7
Chemical Name: 10-Gingerol
Synonyms: 10-GINGEROL;GINGEROL, 10-;10-Gingerol ,98%;10-GINGEROL, HPLC 98%;(+)-(S)-[10]-Gingerol;10-Gingerol USP/EP/BP;[10]-Gingerol Standard;10]-Gingerol >=95% (HPLC);Propionic Acid Impurity 1;10-Gingerol, 10 mM in DMSO
CBNumber: CB6399377
Molecular Formula: C21H34O4
Formula Weight: 350.49
MOL File: 23513-15-7.mol

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10-Gingerol Property

Melting point:: 56-58 °C
Boiling point:: 499.7±35.0 °C(Predicted)
Density: 1.037±0.06 g/cm3(Predicted)
Flash point:: 166℃
storage temp.: 2-8°C
solubility: methanol: soluble5mg/mL, clear, colorless
pka: 10.02±0.20(Predicted)
form: Solid
color: Yellow
Water Solubility: practically insoluble in water
InChI: InChI=1S/C21H34O4/c1-3-4-5-6-7-8-9-10-18(22)16-19(23)13-11-17-12-14-20(24)21(15-17)25-2/h12,14-15,18,22,24H,3-11,13,16H2,1-2H3/t18-/m0/s1
InChIKey: AIULWNKTYPZYAN-SFHVURJKSA-N
SMILES: C(C1=CC=C(O)C(OC)=C1)CC(=O)C[C@@H](O)CCCCCCCCC
LogP: 4.900 (est)

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Safety

Risk Statements: 53
Safety Statements: 24/25
WGK Germany: 3
HS Code: 29145019

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G5798
Product name: [10]-Gingerol
Purity: ≥95% (HPLC)
Packaging: 5mg
Price: $223.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: 42630
Product name: [10]-Gingerol
Purity: analytical standard
Packaging: 10mg
Price: $772
Updated: 2025/07/31

Cayman Chemical

Product number: 11842
Product name: 10-Gingerol
Purity: ≥98%
Packaging: 1mg
Price: $38
Updated: 2024/03/01

Cayman Chemical

Product number: 11842
Product name: 10-Gingerol
Purity: ≥98%
Packaging: 5mg
Price: $166
Updated: 2024/03/01

Sigma-Aldrich

Product number: G5798
Product name: [10]-Gingerol
Purity: ≥95% (HPLC)
Packaging: 10mg
Price: $592
Updated: 2025/07/31

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10-Gingerol Chemical Properties,Usage,Production

Description

10-Gingerol is a phenol that has been found in Z. officinale and has diverse biological activities. It scavenges DPPH , superoxide, and hydroxyl radicals in cell-free assays (IC₅₀s = 10.47, 1.68, and 1.35 μM, respectively) and inhibits oxidative burst induced by N-formyl-Met-Leu-Phe (fMLP; ) in isolated human polymorphonuclear (PMN) neutrophils when used at a concentration of 6 μM. 10-Gingerol inhibits NETosis and the production of reactive oxygen species (ROS) induced by LPS or lupus-relevant stimuli, including ribonucleoprotein-containing immune complexes and anti-phospholipid antibodies, in isolated human neutrophils. It is active against M. avium and M. tuberculosis (MICs = 25 and 50 μg/ml, respectively). 10-Gingerol (200 μM) is also cytotoxic to human MDA-MB-231 and MDA-MB-468 and murine 4T1 and EO771 mammary carcinoma cells.

Chemical Properties

White waxy, soluble in methanol, ethanol, DMSO and other organic solvents, derived from ginger.

Uses

(+)-(S)-[10]-Gingerol has been observed to exhibit anti-oxidant behaviour towards lipids and is effective in suppressing obesity and adipose tissue inflammation.

Definition

ChEBI: (10)-Gingerol is a beta-hydroxy ketone, a member of phenols and a monomethoxybenzene.

Biochem/physiol Actions

[10]-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with anti-inflammatory and antioxidant activity.

in vivo

10-Gingerol (30 mg/kg, i.p., 7 consecutive days) reverses body weight loss, declines disease activity index (DAI), decreasing myeloperoxidase (MPO) activity and malondialdehyde (MDA) level, as well as restoring SOD activity, reduces the serum TNF-α and IL-1β levels, ameliorates mucosa inflammation and/or defect in rats with DSS-induced acute ulcerative colitis^[4].

Animal Model:	Rats with DSS-induced acute ulcerative colitis^[4]
Dosage:	30 mg/kg
Administration:	i.p., 7 consecutive days
Result:	Reversed body weight loss and significantly declined DAI, reduced the serum TNF-α and IL-1β levels, ameliorated mucosa inflammation and/or defect in rats with DSS-induced acute ulcerative colitis in rats with DSS-induced acute ulcerative colitis.

References

[1] SWARNALATHA DUGASANI . Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol[J]. Journal of ethnopharmacology, 2010, 127 2: Pages 515-520. DOI: 10.1016/j.jep.2009.10.004
[2] RAMADAN A ALI. Antineutrophil properties of natural gingerols in models of lupus.[J]. JCI insight, 2021. DOI: 10.1172/jci.insight.138385
[3] R. D. HISERODT R. T R S G Franzblau. Isolation of 6-, 8-, and 10-Gingerol from Ginger Rhizome by HPLC and Preliminary Evaluation of Inhibition of Mycobacterium avium and Mycobacterium tuberculosis[J]. Journal of Agricultural and Food Chemistry, 1998, 46 7: 2504-2508. DOI: 10.1021/jf970948l
[4] MEGAN M. BERNARD David W H Jason R McConnery. [10]-Gingerol, a major phenolic constituent of ginger root, induces cell cycle arrest and apoptosis in triple-negative breast cancer cells[J]. Experimental and molecular pathology, 2017, 102 2: Pages 370-376. DOI: 10.1016/j.yexmp.2017.03.006

10-Gingerol Preparation Products And Raw materials

Raw materials

Preparation Products

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10-Gingerol Suppliers

Canada 1 China 245 Germany 1 India 3 United Kingdom 5 United States 18 USA 1 Global 274

Wuhan ChemFaces Biochemical Co., Ltd.

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Chembest Research Laboratories Limited

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Adamas Reagent, Ltd.

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Syntechem Co.,Ltd

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Sichuan Kulinan Technology Co., Ltd

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China Langchem Inc.

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Shenzhen Sungening Bio-Tech Co., Ltd

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ShangHai YuanYe Biotechnology Co., Ltd.

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View Lastest Price from 10-Gingerol manufacturers

Lianyungang Kaiyu Environmental Tech Co., Ltd.

Product: Gingerol 23513-15-7
Price: US $1200.00-1100.00/ton
Min. Order: 1ton
Purity: 99%
Supply Ability: 1000T/M
Release date: 2025-11-10

Shanghai Standard Technology Co., Ltd.

Product: 10-Gingerol 23513-15-7
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-12-30

Career Henan Chemical Co

Product: 10-Gingerol 23513-15-7
Price: US $2.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1 ton
Release date: 2018-08-20

23513-15-7, 10-GingerolRelated Search:

DIPHENYLCYCLOPROPENONE Diphenylsilanediol 4-Methoxyphenylacetone 4'-Hydroxyacetophenone Benzoylcyclohexane Phenylfluorone 6-Gingerol Diacetone Alcohol CHLOROPHOSPHONAZO III 2'-Hydroxyacetophenone 8-GINGEROL 4-tetradecylphenol Tetradecane Vanillylacetone 3-TETRADECANONE gingerol 6-GINGEROL,(+/-) 8-PARADOL

10-GINGEROL, HPLC 98%

10-GINGEROL

5-HYDROXY-1-(4-HYDROXY-3-METHOXYPHENYL)-3-TETRADECANONE

(5S)-1-(3-Methoxy-4-hydroxyphenyl)-5-hydroxytetradecane-3-one

(5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone

(S)-1-(3-Methoxy-4-hydroxyphenyl)-5-hydroxytetradecane-3-one

(S)-12-Oxo-14-(3-methoxy-4-hydroxyphenyl)tetradecane-10-ol

(5S)-5-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)tetradecan-3-one

(5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one

10-Gingerol ,98%

5-hydroxy-1-(4-hydroxy-3-Methoxyphenyl)tetradecan-3-one

(S)-5-hydroxy-1-(4-hydroxy-3-Methoxyphenyl)tetradecan-3-one

(+)-(S)-[10]-Gingerol

(s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone

GINGEROL, 10-

10-Gingerol, 98%, from Zingiber officinale Roscoe

[10]-Gingerol Standard

3-Tetradecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-

10]-Gingerol >=95% (HPLC)

10-Gingerol USP/EP/BP

Propionic Acid Impurity 1

10-Gingerol, 10 mM in DMSO

23513-15-7

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

The group of Ginerols

Miscellaneous Natural Products