tetrahydroharmine
- Product Name
- tetrahydroharmine
- CAS No.
- 17019-01-1
- Chemical Name
- tetrahydroharmine
- Synonyms
- HARMALINE-001;Tetrahydroharmin;tetrahydroharmine;Harmine Impurity1;1,2,3,4-Tetrahydroharmine;Tetrahydroharmine solution;Tetrahydroharmine, 10 mM in DMSO;7-methoxy-1-methyl-1H,2H,3H,4H,9H-pyrido[3,4-b]indole;2,3,4,9-tetrahydro-7-methoxy-1-methyl-1H-Pyrido[3,4-b]indole;7-methoxy-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
- CBNumber
- CB01331624
- Molecular Formula
- C13H16N2O
- Formula Weight
- 216.28
- MOL File
- 17019-01-1.mol
tetrahydroharmine Property
- Melting point:
- 199 °C
- Boiling point:
- 399.2±37.0 °C(Predicted)
- Density
- 1.145±0.06 g/cm3(Predicted)
- storage temp.
- Amber Vial, -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 18.03±0.40(Predicted)
- color
- White to Off-White
- Stability:
- Light Sensitive
Safety
- WGK Germany
- WGK 2
- Storage Class
- 3 - Flammable liquids
- Hazard Classifications
- Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H370Causes damage to organs
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
N-Bromosuccinimide Price
- Product number
- 14449
- Product name
- tetrahydro-Harmine
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $46
- Updated
- 2024/03/01
- Product number
- 14449
- Product name
- tetrahydro-Harmine
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $79
- Updated
- 2024/03/01
- Product number
- 14449
- Product name
- Tetrahydroharmine
- Purity
- ≥98%
- Packaging
- 50 mg
- Price
- $299
- Updated
- 2024/03/01
- Product number
- 14449
- Product name
- tetrahydro-Harmine
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $162
- Updated
- 2024/03/01
- Product number
- T310285
- Product name
- Tetrahydroharmine
- Packaging
- 100mg
- Price
- $580
- Updated
- 2021/12/16
tetrahydroharmine Chemical Properties,Usage,Production
Description
This carboline alkaloid is present in Banisteria caapi, a plant indigenous toSouth America. It is dextrorotatory with [o:]l>s + 32° (c 1.0, CHCI3). One methoxyl group, a methyl group and two imino groups are present in the molecule.
Uses
Tetrahydroharmine is a β-Carboline derivative. β-Carboline alkaloids are inhibitors of human monoamine oxidase enzymes. β-carboline derivatives were also reported to have antiviral and fungicidal activity. Tetrahydroharmine is related to 3,4-Dihydroharmine (D449718).
IC 50
MAO-B: 74 nM (IC50)
References
Hochstein, Paradies., J. Arner. Chern. Soc., 79, 5735 (1957)
Bernauer., Helv. Chirn. Acta, 47, 1075 (1960)
Koblicova, Trojanek., Chern. Ind., 1342 (1966)
tetrahydroharmine Preparation Products And Raw materials
Raw materials
Preparation Products
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