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RESCINNAMINE

Product Name
RESCINNAMINE
CAS No.
24815-24-5
Chemical Name
RESCINNAMINE
Synonyms
Rozex;Apolon;Rescin;Tuareg;Anapral;Cartric;Moderil;Resipal;ANAPREL;Apoterin
CBNumber
CB2344278
Molecular Formula
C35H42N2O9
Formula Weight
634.72
MOL File
24815-24-5.mol
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RESCINNAMINE Property

Melting point:
238-239°C
alpha 
D24 -97° (c = 1 in chloroform)
Boiling point:
669.26°C (rough estimate)
Density 
1.2161 (rough estimate)
refractive index 
1.5300 (estimate)
storage temp. 
2-8°C
pka
pKa 6.4 (Uncertain)
Boiling Point
756.8±60.0 °C(Predicted)
Density
1.31±0.1 g/cm3(Predicted)
Melting Point
238.5 °C
Stability:
Stable, but darkens slowly in light. Incompatible with strong oxidizing agents.
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Safety

Hazard Codes 
Xn
Risk Statements 
25-20/21/22
Safety Statements 
22-45-36
RIDADR 
1544
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

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RESCINNAMINE Chemical Properties,Usage,Production

Chemical Properties

white to cream powder

Uses

Rescinnamine occurs in the roots of a num ber of Rauwolfia species. Therapeutically, itis used as an antihypertensive agent.

brand name

Moderil (Pfizer).

General Description

Odorless white to cream colored crystalline powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

The neat material darkens slowly on exposure to light. In solution this occurs more rapidly. .

Health Hazard

The pharmacological properties of rescinnamine are similar to those of reserpine, butthe side effects are low. It acts as a sedativeand hypotensive. A dose of 0.25 mg/day mayproduce the effect of sleepiness in humans.Excessive doses may produce depression,nightmare, nausea, diarrhea, and hypotension.
LD50 value, oral (rats): 1000 mg/kg
The carcinogenicity of rescinnamine inanimals or humans is unknown.

Fire Hazard

Flash point data for RESCINNAMINE are not available. RESCINNAMINE is probably combustible.

Purification Methods

Crystallise it from *benzene, MeOH or aqueous Me2CO. The hydrochloride has m 232o(dec) (from MeOH) and [] D -74o (MeOH). It is an antihypertensive. [Klohs et al. J Am Chem Soc 77 2241 1955, Beilstein 25 III/IV 1323.]

RESCINNAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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RESCINNAMINE Suppliers

Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725;010-86181995
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12341
Advantage
58
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-58378339;025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3818
Advantage
55
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
051085629785,051085625359,QQ974229108,QQ1373125882
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
19214
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58
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7235
Advantage
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EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8455
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60
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
400-666-5481
Fax
021-55068248
Email
shyysw@163.com
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China
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29900
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Raw material medicin reagent co.,Ltd
Tel
025-57798860
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sales@njromanme.com
Country
China
ProdList
4615
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Shanghai ChengShao Biological Technology Co., Ltd.
Tel
021-61847300 13341622919
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021-61847300
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shcss01@163.com
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China
ProdList
4808
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Shanghai Jizhi Biochemical Technology Co. Ltd.
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400-900-4166
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3007522970@qq.com
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Hubei Jusheng Technology Co.,Ltd.
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86-18871470254
Fax
027-59599243
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sales@jushengtech.com
Country
CHINA
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28236
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24815-24-5, RESCINNAMINERelated Search:


  • Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]oxy]-, methyl ester, (3β,16β,17α,18β,20α)-
  • 17alpha-dimethoxy-18beta-((1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)oxy)-1
  • 3,4,5-Trimethoxycinnamic acid, methyl reserpate
  • 3,4,5-Trimethoxycinnamoyl methyl reserpate
  • 3,4,5-trimethoxycinnamoylmethylreserpate
  • 3,4,5-Trimethylcinnamic acid, ester with methyl reserpate
  • 3,4,5-trimethylcinnamicacid,esterwithmethylreserpate
  • 3,4,5-Trimethylcinnamoyl methyl reserpate
  • 3,4,5-trimethylcinnamoylmethylreserpate
  • 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-, methyl ester, 3,4,5-trimethoxycinnamate (ester)
  • 3-beta,20-alpha-Yohimban-16-beta-carboxylic acid, 18-beta-hydroxy-11,17-alpha-dimethoxy-,methyl ester, 3,4,5-trimethoxycinnamate
  • 3beta,20alpha-yohimban-16beta-carboxylicacid,18beta-hydroxy-11,17alpha-dimeth
  • 3beta,20alpha-yohimban-16beta-carboxylicacidmethylester
  • Anapral
  • Apolon
  • Apoterin
  • Apoterin S
  • Benz(g)indolo(2,3-a)quinolizine-1-carboxylic acid, 1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-3-hydroxy-2,11-dimethoxy-, methyl ester, 3,4,5-trimethoxycinnamate
  • Cartric
  • Cinamine
  • Cinatabs
  • Cinnaloid
  • Cinnasil
  • imethoxy-,methylester,3,4,5-trimethoxycinnamate(ester)
  • Methyl 11,17-dimethoxy-18-([(2E)-3-(3,4,5-trimethoxyphenyl)-2-propenoyl]oxy)yohimban-16-carboxylate
  • Methyl 18beta-hydroxy-11,17alpha-dimethoxy-3beta,20alpha-yohimban-16beta-carboxylate
  • Methyl 18-O-(3,4,5-trimethoxycinnamoyl)reserpate
  • Methyl trimethoxycinnamoylreserpate
  • methyl18-o-(3,4,5-trimethoxycinnamoyl)reserpate
  • methyl18-o-(3,4,5-trimethoxycinnamoylreserpate
  • methylester,3,4,5-trimethoxycinnamate(ester),(e)-oxy
  • methyltrimethoxycinnamoylreserpate
  • Moderil
  • Normorescina
  • Paresinan
  • Raupyrol
  • Raurescin
  • Raurescine
  • Recinnamine
  • Recitensina
  • Rescaloid
  • Rescamin
  • Rescidan
  • Rescin
  • Rescinnamin
  • Rescinpal
  • Rescisan
  • Rescitens
  • Resealoid
  • resepinine(c35alkaloid)
  • Reserpinene
  • Reserpinin
  • Reserpinine (C35 alkaloid)
  • reserpinine[c35alkaloid]
  • Resipal
  • Reskinnamin
  • Rozex
  • Scinnamina