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4-(Methylsulfonyl)phenol

Product Name
4-(Methylsulfonyl)phenol
CAS No.
14763-60-1
Chemical Name
4-(Methylsulfonyl)phenol
Synonyms
4-(METHYLSULFONYL)PHENOL;4-METHYLSULPHONYLPHENOL;4-Mesylphenol;4-Methylsulfonylphen;p-Methylsulphonylphenol;4-(methylsulfonyl)-pheno;4-METHANESULFONYL-PHENOL;p-(Methylsulfonyl)phenol;p-(methylsulfonyl)-pheno;4-METHANESULPHONYLPHENOL
CBNumber
CB0135245
Molecular Formula
C7H8O3S
Formula Weight
172.2
MOL File
14763-60-1.mol
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4-(Methylsulfonyl)phenol Property

Melting point:
90-95 °C
Boiling point:
272.52°C (rough estimate)
Density 
1.3692 (rough estimate)
refractive index 
1.5151 (estimate)
RTECS 
SM1530000
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO, Methanol
form 
Powder
pka
pK1:7.83 (25°C)
color 
Tan to pink-brown
Water Solubility 
slight
BRN 
1866322
LogP
0.886 (est)
CAS DataBase Reference
14763-60-1(CAS DataBase Reference)
NIST Chemistry Reference
4-(Methylsulfonyl)phenol(14763-60-1)
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
24/25-26
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29309090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
H1367
Product name
4-Hydroxyphenyl Methyl Sulfone
Purity
>98.0%(GC)
Packaging
5g
Price
$40
Updated
2024/03/01
TCI Chemical
Product number
H1367
Product name
4-Hydroxyphenyl Methyl Sulfone
Purity
>98.0%(GC)
Packaging
25g
Price
$132
Updated
2024/03/01
Alfa Aesar
Product number
H32935
Product name
4-(Methylsulfonyl)phenol, 97%
Packaging
10g
Price
$193
Updated
2021/12/16
Alfa Aesar
Product number
H32935
Product name
4-(Methylsulfonyl)phenol, 97%
Packaging
1g
Price
$32
Updated
2021/12/16
TRC
Product number
M329450
Product name
4-(Methylsulfonyl)phenol
Packaging
1g
Price
$55
Updated
2021/12/16
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4-(Methylsulfonyl)phenol Chemical Properties,Usage,Production

Chemical Properties

Tan to pink-brown powder

Uses

4-(Methylsulfonyl)phenol is a reagent in the synthesis of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists. Also a reagent in the synthesis of novel 2-(pyridine-2-yl)-1H-benzimidazole derivatives as potent glucokinase activators.

Reactions

The reaction of 4-(methylsulfonyl)phenol (17.2 g, 100.0 mmol) with p-Toluenesulfonic anhydride as outlined in the general procedure provided 4-(methylsulfonyl)phenyl 4-methylbenzenesulfonate (26.1 g, 81%).

4-(Methylsulfonyl)phenol Preparation Products And Raw materials

Raw materials

Hydrogen peroxide Acetyl chloride Chloroform Carbon tetrachloride Ethyl acetate Hydrochloric acid Acetic acid Sodium periodate Sodium hydroxide 4-(Methylthio)phenol Magnesium sulfate

Preparation Products

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4-(Methylsulfonyl)phenol Suppliers

Americas 1 Belgium 2 China 102 Europe 3 France 1 Germany 3 India 4 Japan 3 Switzerland 1 United Kingdom 17 United States 28 USA 1 Global 166
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View Lastest Price from 4-(Methylsulfonyl)phenol manufacturers

Henan Fengda Chemical Co., Ltd
Product
4-(Methylsulfonyl)phenol 14763-60-1
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-24
Hebei Zhanyao Biotechnology Co. Ltd
Product
4-Methylsulfonylphenol 14763-60-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-10-19
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Methylsulfonylphenol 14763-60-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-10

14763-60-1, 4-(Methylsulfonyl)phenolRelated Search:

Bis(4-hydroxyphenyl) Sulfone 4,4'-BIS(3-AMINOPHENOXY)DIPHENYL SULFONE BIS(4-HYDROXY-3,5-DIMETHYLPHENYL) SULFONE 4,4'-Sulphonylbis(2,6-dibromophenol) Bis[4-(4-aminophenoxy)phenyl]sulfone 4-METHOXYPHENYLMETHYLSULFONE 4-(Methylsulfonyl)phenol REACTIVE VIOLET 5 3,3'-Diamino-4,4'-dihydroxydiphenyl sulfone 4-(methylsulphonyl)-2-nitrophenol 3-AMINO-4-METHOXYPHENYL ETHYL SULFONE 2-AMINO-4-(ETHYLSULFONYL)PHENOL 2-PROPANONE, 1-[(4-METHOXYPHENYL)SULFONYL]- P-FLUOROPHENYL-P-METHOXYPHENYL SULFONE ETHYL 2-[(4-METHOXYPHENYL)SULFONYL]ACETATE 4-((4-[(3-CHLORO-2,2-DIMETHYLPROPANOYL)OXY]-3,5-DIMETHYLPHENYL)SULFONYL)-2,6-DIMETHYLPHENYL 3-CHLORO-2,2-DIMETHYLPROPANOATE AKOS BBS-00002840

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