ChemicalBook > CAS DataBase List > 3-(2,4-dimethoxybenzylidene)anabaseine

3-(2,4-dimethoxybenzylidene)anabaseine

Product Name
3-(2,4-dimethoxybenzylidene)anabaseine
CAS No.
156223-05-1
Chemical Name
3-(2,4-dimethoxybenzylidene)anabaseine
Synonyms
DMXB;DMXB-A;DMBX-A;GTS-21HCl;GTS 21 2HCl;GTS-21 (DMXB-A);DMBX-anabaseine;GTS 21 2HCl(DMXBA);GTS21;GTS 21;GTS-21;GTS 21 2hydrochloride
CBNumber
CB01372542
Molecular Formula
C19H22Cl2N2O2
Formula Weight
0
MOL File
156223-05-1.mol
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3-(2,4-dimethoxybenzylidene)anabaseine Property

Melting point:
216-217℃ (decomposition)
storage temp. 
2-8°C
solubility 
H2O: >5mg/mL
form 
powder
color 
faint yellow to dark yellow
InChIKey
RPYWXZCFYPVCNQ-RVDMUPIBSA-N
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Safety

WGK Germany 
3
RTECS 
DW1764860
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0326
Product name
GTS-21
Purity
≥97% (HPLC)
Packaging
5mg
Price
$90.5
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0326
Product name
GTS-21
Purity
≥97% (HPLC)
Packaging
25mg
Price
$370
Updated
2024/03/01
Sigma-Aldrich
Product number
5.05277
Product name
GTS-21 Dihydrochloride (DMBX-A) - CAS 156223-05-1 - Calbiochem
Packaging
10MG
Price
$108
Updated
2022/05/15
Cayman Chemical
Product number
21570
Product name
GTS-21 (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$64
Updated
2024/03/01
Cayman Chemical
Product number
21570
Product name
GTS-21 (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$113
Updated
2024/03/01
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3-(2,4-dimethoxybenzylidene)anabaseine Chemical Properties,Usage,Production

Uses

GTS-21 has been used:

  • as an α7 nicotinic acetylcholine receptors (nAChR) partial agonist to elucidate its anti-inflammatory effects in mouse macrophages
  • to test its protective effect on the renal injury induced by lipopolysaccharide (LPS)
  • to test its effect on microvascular inflammation?in endotoxemia induced by LPS

Biochem/physiol Actions

GTS-2, a derivative of anisine is an immunomodulatory drug. It is used for treating pancreatitis and septicemia. GTS-2 inhibits the pro-inflammatory cytokines especially the interleukin-6 (IL6) and tumor necrosis factor (TNF) in sepsis and endotoxemia.

3-(2,4-dimethoxybenzylidene)anabaseine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(2,4-dimethoxybenzylidene)anabaseine Suppliers

China 70 South Korea 1 United Kingdom 1 United States 13 Global 85
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View Lastest Price from 3-(2,4-dimethoxybenzylidene)anabaseine manufacturers

Wuhan Haorong Biotechnology Co.,Ltd
Product
Dihydrochloride / 3-(2,4-dimethoxybenzylidene)anabaseine 156223-05-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000
Release date
2023-08-11
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
Product
GTS-21 156223-05-1
Price
US $0.00/KG
Min. Order
100g
Purity
98%+
Supply Ability
100kg
Release date
2021-03-09
Wuhan Senwayer Century Chemical Co.,Ltd
Product
GTS-21 156223-05-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99% min
Supply Ability
20 tons
Release date
2022-10-19

156223-05-1, 3-(2,4-dimethoxybenzylidene)anabaseineRelated Search:

2-Methoxyphenylacetic acid 4'-Hydroxyacetophenone Sodium benzoate 3-(2,4-dimethoxybenzylidene)anabaseine

  • 3-(2,4-dimethoxybenzylidene)anabaseine
  • 3-[(3E)-3-[(2,4-dimethoxyphenyl)methylidene]-5,6-dihydro-4H-pyridin-2-yl]pyridine dihydrochloride
  • 3-(2,4-Dimethoxy-benzyl)-3,4,5,6-tetrahydro-[2,3']bipyridinyl
  • 3-(2,4)-DiMethoxybenzylidineanabaseine
  • GTS-21 (DMXB-A)
  • 3-(2,4-DiMethoxy-benzyl)-3,4,5,6-tetrahydro-[2,3']bipyridinyl Dihydrochloride
  • (3E)-3-[(2,4-Dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-Bipyridine dihydrochloride
  • DMBX-anabaseine
  • DMXB-A
  • GTS 21 DIHYDROCHLORIDE;DMXB-A;DMBX-ANABASEINE
  • GTS 21 2HCl(DMXBA)
  • GTS21;GTS 21;GTS-21
  • 3-(2,4-Dimethoxybenzylidene)-anabaseine dihydrochloride
  • DMXB
  • GTS 21 dihydrochloride
  • 3-[(2,4-dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-Bipyridine Dihydrochloride
  • GTS 21 2HCl
  • GTS 21 2hydrochloride
  • GTS-21 (hydrochloride)
  • GTS-21HCl
  • DMBX-A
  • (E)-3-(2,4-Dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3'-bipyridine dihydrochloride
  • 3-(2,4-dimethoxybenzylidene)anabaseine / 99% / 156223-05-1 in sock
  • GTS 21 dihydrochloride(DMXB-A)
  • inhibit,5-hydroxytryptamine Receptor,anti?inflammatory,cognition,GTS-21,nAChR,GTS21 dihydrochloride,Serotonin Receptor,fibrosis,Inhibitor,GTS 21,5-HT Receptor,Nicotinic acetylcholine receptors,lung,injury,GTS21,pulmonary
  • Dihydrochloride / 3-(2,4-dimethoxybenzylidene)anabaseine
  • GTS-21 dihydrochloride (DMBX-A)
  • (E)-3-(2,4-Dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3'-bipyridine dihydrochloride
  • 156223-05-1
  • C19H22Cl2N2O2
  • C19H20N2O22HCl
  • Inhibitors