ChemicalBook > CAS DataBase List > 6-Bromoimidazo[1,2-a]pyridine

6-Bromoimidazo[1,2-a]pyridine

Product Name: 6-Bromoimidazo[1,2-a]pyridine
CAS No.: 6188-23-4
Chemical Name: 6-Bromoimidazo[1,2-a]pyridine
Synonyms: BUTTPARK 154\50-43;6-Bromoimidazo[1,2-a]pyri...;6-Bromoimidazo[1.2-alpyridine;6-BROMOIMIDAZO[1,2-A]PYRIDINE;6-BroMoiMidazolo[1,2-a]pyridine;6-BROMO-INIDAZO[1,2-A]-PYRIDINE;6-BroMo IMidazole[1,2-a]Pyridine;IMidazo[1,2-a]pyridine, 6-broMo-;6-Bromoimidazo[1,2-a]pyridine;6- BROMINE IMIDAZOLYL [ 1,2-A ] PYRIDINE
CBNumber: CB0142414
Molecular Formula: C7H5BrN2
Formula Weight: 197.03
MOL File: 6188-23-4.mol

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6-Bromoimidazo[1,2-a]pyridine Property

Melting point:: 76-78 °C
Boiling point:: 165 °C(Press: 1.5 Torr)
Density: 1.69±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
pka: 5.10±0.50(Predicted)
form: crystalline needles
color: Faint beige
Water Solubility: slightly soluble in water.
InChI: InChI=1S/C7H5BrN2/c8-6-1-2-7-9-3-4-10(7)5-6/h1-5H
InChIKey: FXPMFQUOGYGTAM-UHFFFAOYSA-N
SMILES: C12=NC=CN1C=C(Br)C=C2
CAS DataBase Reference: 6188-23-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 22-26-36/37/39
WGK Germany: 3
Hazard Note: Harmful
HazardClass: IRRITANT
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 750972
Product name: 6-Bromoimidazo[1,2-a]pyridine
Purity: 97%
Packaging: 500mg
Price: $71
Updated: 2023/06/20

TCI Chemical

Product number: B5225
Product name: 6-Bromoimidazo[1,2-a]pyridine
Purity: min. 98.0 %
Packaging: 1G
Price: $38
Updated: 2025/07/31

TCI Chemical

Product number: B5225
Product name: 6-Bromoimidazo[1,2-a]pyridine
Purity: min. 98.0 %
Packaging: 10G
Price: $99
Updated: 2025/07/31

TRC

Product number: B696310
Product name: 6-Bromoimidazo[1,2-a]pyridine
Packaging: 250mg
Price: $55
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140150
Product name: 6-Bromoimidazo[1,2-a]pyridine
Packaging: 10g
Price: $40
Updated: 2021/12/16

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6-Bromoimidazo[1,2-a]pyridine Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

It is used in organic syntheses and as pharmaceutical intermediates. The best results were obtained with lactams that could be introduced on the 6-bromoimidazo[1,2-a]pyridine. 1,2-dihydro-5-imidazo [1,2-a]pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile hydrochloride monohydrate 6 was synthesized in 5 steps from 6-bromoimidazo[1,2-a] pyridine using [2- 14 C] cyanoacetamide as the source of the radiolabel.

Synthesis

107-20-0

1072-97-5

6188-23-4

(1) Preparation of 6-bromoimidazo[1,2-a]pyridine (4): 2.00 g of 2-amino-5-bromopyridine (3) was dissolved in 35 mL of ethanol, and 2.52 mL of 6.1 mol/L aqueous chloroacetaldehyde solution was added. The reaction mixture was heated to reflux for 3 hours. After completion of the reaction, the reaction mixture was concentrated and saturated aqueous NaHCO3 solution was added to the residue and extracted with ethyl acetate. After conventional post-treatment, 2.30 g of 6-bromoimidazo[1,2-a]pyridine was obtained as a brown powder (yield: 100%).LCMS (ESI) m/z (M + H)+: 368.93.

References

[1] Patent: US2011/98471, 2011, A1. Location in patent: Page/Page column 56
[2] Patent: US2014/134133, 2014, A1. Location in patent: Paragraph 0399
[3] Patent: WO2012/116237, 2012, A2. Location in patent: Page/Page column 118
[4] Patent: US2015/320727, 2015, A1. Location in patent: Paragraph 0553; 0554
[5] Patent: WO2008/14219, 2008, A2. Location in patent: Page/Page column 44-45

6-Bromoimidazo[1,2-a]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-Bromoimidazo[1,2-a]pyridine manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 6-Bromoimidazo[1,2-a]pyridine 6188-23-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

Shanghai UCHEM Inc.

Product: 6-Bromoimidazo[1,2-a]pyridine 6188-23-4
Price: US $12.00-217.00/g
Min. Order: 25g
Purity: 0.98
Supply Ability: 25kg
Release date: 2024-10-25

Dideu Industries Group Limited

Product: 6-Bromoimidazo[1,2-a]pyridine 6188-23-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-25

6188-23-4, 6-Bromoimidazo[1,2-a]pyridineRelated Search:

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BUTTPARK 154\50-43

6-BROMOIMIDAZO[1,2-A]PYRIDINE

6-BROMO-INIDAZO[1,2-A]-PYRIDINE

6- BROMINE IMIDAZOLYL [ 1,2-A ] PYRIDINE

6-Bromoimidazo[1,2-a]pyri...

6-BroMoiMidazolo[1,2-a]pyridine

IMidazo[1,2-a]pyridine, 6-broMo-

6-BroMo IMidazole[1,2-a]Pyridine

6-Bromoimidazo[1,2-a]pyridine ISO 9001：2015 REACH

6-Bromoimidazo[1.2-alpyridine

6-Bromoimidazo[1,2-<i>a</i>]pyridine

6188-23-4

Heterocycle-Pyridine series

CHIRAL CHEMICALS

Building Blocks

Imidazo[x,x-y]pyridine

blocks

Bromides

Imidazoles

Pyridines