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1-Hexadecylpyridinium bromide

Product Name
1-Hexadecylpyridinium bromide
CAS No.
140-72-7
Chemical Name
1-Hexadecylpyridinium bromide
Synonyms
HEXADECYLPYRIDINIUM BROMIDE;CETYLPYRIDINIUM BROMIDE;Hexadecylpyridinium Bromide Hydrate;bromocet;hexadecylpyridine bromide;N-HEXADECYLPYRIDINIUM BROMIDE;tspb;cetasol;cetazol;seprisan
CBNumber
CB0322113
Molecular Formula
C21H38BrN
Formula Weight
384.44
MOL File
140-72-7.mol
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1-Hexadecylpyridinium bromide Property

Melting point:
63-69 °C
storage temp. 
Inert atmosphere,Room Temperature
solubility 
soluble in Chloroform,Methanol,Acetone,Ethanol
form 
powder to crystal
color 
White to Almost white
Water Solubility 
5 g/L (20 ºC)
BRN 
3778948
InChI
InChI=1S/C21H38N.BrH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-22-20-17-15-18-21-22;/h15,17-18,20-21H,2-14,16,19H2,1H3;1H/q+1;/p-1
InChIKey
DVBJBNKEBPCGSY-UHFFFAOYSA-M
SMILES
[N+]1(CCCCCCCCCCCCCCCC)C=CC=CC=1.[Br-]
LogP
1.699 (est)
CAS DataBase Reference
140-72-7(CAS DataBase Reference)
EPA Substance Registry System
Cetylpyridinium bromide (140-72-7)
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Safety

Hazard Codes 
T+,Xi,Xn
Risk Statements 
22-26-36/37/38-20/21/22
Safety Statements 
26-28-36/37-45-36/37/39-22-36
RIDADR 
2811
WGK Germany 
3
RTECS 
UU4848000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29333999
Hazardous Substances Data
140-72-7(Hazardous Substances Data)
Toxicity
mouse,LD50,unreported,126mg/kg (126mg/kg),Pharmazie. Vol. 40, Pg. 273, 1985.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H330Fatal if inhaled

H335May cause respiratory irritation

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
52340
Product name
Hexadecylpyridinium bromide
Purity
≥97.0%
Packaging
100g
Price
$99.9
Updated
2025/07/31
TCI Chemical
Product number
H0162
Product name
Hexadecylpyridinium Bromide Hydrate
Purity
>96.0%(HPLC)(T)
Packaging
25g
Price
$27
Updated
2025/07/31
TCI Chemical
Product number
H0162
Product name
Hexadecylpyridinium Bromide Hydrate
Purity
>96.0%(HPLC)(T)
Packaging
500g
Price
$203
Updated
2025/07/31
Frontier Specialty Chemicals
Product number
JK113112
Product name
1-Hexadecylpyridiniumbromide
Packaging
500g
Price
$399
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0018000
Product name
1-HEXADECYLPYRIDIN-1-IUM BROMIDE
Purity
95.00%
Packaging
1MG
Price
$586.97
Updated
2021/12/16
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1-Hexadecylpyridinium bromide Chemical Properties,Usage,Production

Description

1-Hexadecylpyridinium bromide is a cationic surfactant capable of bactericidal activity and has been used for ion exchange. As a bactericidal agent, it reduces the surface tension between pathogenic membranes and their environments. This interaction disrupts membrane integrity and osmoregulation, leading to cell lysis. It has also been shown to quickly and efficiently remove metal ions from solutions. The compound removes cations from the solution through a cation/surfactant complex, which precipitates from an aqueous phase into an organic phase and can subsequently be extracted. It is an effective ion exchange agent for extracting DNA and proteins.

Chemical Properties

white to cream coloured powder

Uses

Hexadecylpyridinium bromide (HDPB) is a biochemical assay reagent.

Definition

ChEBI: A pyridinium salt that has N-hexadecylpyridinium as the cation and bromide as the anion.

Synthesis

110-86-1

112-82-3

140-72-7

General method: 1-bromohexadecane (0.01 mol) and pyridine (0.011 mol) were added sequentially to 25 mL of anhydrous acetonitrile and heated to reflux for 24 hours. Upon completion of the reaction, the solvent was removed by evaporation, the residue was co-evaporated with benzene to remove residual water, and finally the N-hexadecyl pyridine bromide salt was recrystallized from acetone.

References

[1] Molecules, 2010, vol. 15, # 3, p. 1967 - 1972
[2] Green Chemistry, 2009, vol. 11, # 1, p. 83 - 90
[3] European Journal of Medicinal Chemistry, 2013, vol. 66, p. 46 - 55
[4] Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1952, vol. 291, p. 1,4
[5] Journal of the American Pharmaceutical Association (1912-1977), 1942, vol. 31, p. 51

1-Hexadecylpyridinium bromide Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Hexadecylpyridinium bromide Suppliers

Beijing Minruida Technology Co., Ltd.
Tel
010-82387566 18001021521;
Fax
82387566-801
Email
sales@mreda.com.cn
Country
China
ProdList
10083
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58
HUBEI ZHENBO CHEM CO,LTD
Tel
18086513998
Email
280306684@qq.com
Country
China
ProdList
290
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58
Shanghai Yuanyuan Biotechnology Co. , Ltd.
Tel
021-58796960 13585883992
Email
herochem021@163.com
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China
ProdList
31
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LANZHOU DAYUAN NEW MATERIAL TECHNOLOGY CO.,LTD
Tel
13992067598
Email
wpthisage@163.com
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China
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5
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58
Beijing Jingtu Hengsheng Commerce&Trade Co.,Ltd.
Tel
00-13911456598 13911456598
Email
13911456598@163.cn
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China
ProdList
2530
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Jinan Dexinjia Bio&Tech Co., Ltd
Tel
0531-82371986 15269101859
Fax
0531-82375893
Email
3276840968@qq.com
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China
ProdList
1604
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Tianshui YiYao Chemical Co., Ltd.
Tel
0938-0938-8493022 1685585981;15379872136
Email
xiaoshi079@163.com
Country
China
ProdList
2018
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58
Shanghai Yanze Chemical Co., Ltd
Tel
021-13621551597 19962611955
Email
260924549@qq.com
Country
China
ProdList
1633
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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62
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View Lastest Price from 1-Hexadecylpyridinium bromide manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
1-Hexadecylpyridinium bromide 140-72-7
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-23
Hebei Fengjia New Material Co., Ltd
Product
1-Hexadecylpyridinium bromide 140-72-7
Price
US $5.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
1000
Release date
2024-09-10
Hebei Chuanghai Biotechnology Co., Ltd
Product
1-Hexadecylpyridinium bromide 140-72-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-15

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