ChemicalBook > CAS DataBase List > 2-Chloropyrimidine-5-carbaldehyde

2-Chloropyrimidine-5-carbaldehyde

Product Name
2-Chloropyrimidine-5-carbaldehyde
CAS No.
933702-55-7
Chemical Name
2-Chloropyrimidine-5-carbaldehyde
Synonyms
2-Chloropyrimidine-5-carb...;2-Chloropyrimidine-5-carbaldehyde;2-Chloro-5-pyrimidinecarbaldehyde;2-Chloropyrimidine-5-carboxaldehyde;2-chloro-5-pyrimidinecarboxaldehyde;2-ChloropyriMidine-5-carboxyaldehyde;5-Pyrimidinecarboxaldehyde, 2-chloro-
CBNumber
CB01454938
Molecular Formula
C5H3ClN2O
Formula Weight
142.54
MOL File
933702-55-7.mol
More
Less

2-Chloropyrimidine-5-carbaldehyde Property

Boiling point:
318.2±15.0 °C(Predicted)
Density 
1.432
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-3.03±0.22(Predicted)
form 
Powder or Crystalline Powder
color 
White to yellow
InChI
InChI=1S/C5H3ClN2O/c6-5-7-1-4(3-9)2-8-5/h1-3H
InChIKey
LJYQVOPFBNMTKJ-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=C(C=O)C=N1
More
Less

Safety

HS Code 
29335990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
C596410
Product name
2-Chloropyrimidine-5-carbaldehyde
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
C596410
Product name
2-Chloropyrimidine-5-carbaldehyde
Packaging
500mg
Price
$200
Updated
2021/12/16
TRC
Product number
C596410
Product name
2-Chloropyrimidine-5-carbaldehyde
Packaging
50mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
4H15-5-19
Product name
2-Chloropyrimidine-5-carbaldehyde
Packaging
5G
Price
$500
Updated
2021/12/16
ChemScene
Product number
CS-0019369
Product name
2-Chloropyrimidine-5-carbaldehyde
Purity
99.77%
Packaging
10g
Price
$345
Updated
2021/12/16
More
Less

2-Chloropyrimidine-5-carbaldehyde Chemical Properties,Usage,Production

Uses

2-Chloropyrimidine-5-carbaldehyde is an important organic reagent that can be used as a building block for the synthesis of many organic compounds, such as 2-(Dimethylamino)pyrimidine-5-carbaldehyde, 2-Aminopyrimidine-5-carboxaldehyde and so on.

Synthesis

131467-06-6

933702-55-7

General procedure for the synthesis of 2-chloropyrimidine-5-carbaldehyde from 2-chloro-5-vinylpyrimidine: 2-chloro-5-vinylpyrimidine (0.1 g, 0.7 mmol) was dissolved in a mixed solvent of dioxane (1 mL) and water (1 mL) at room temperature, and 2,6-dimethylpyridine (0.188 g, 1.76 mmol), osmium tetroxide (3.5 mg 0.007 mmol) and sodium periodate (0.59 g, 2.81 mmol). The reaction mixture was stirred at room temperature for 2-3 hours. After completion of the reaction, the reaction was quenched with ethyl acetate and water. The organic layer was separated and washed sequentially with water and brine. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography to afford 2-chloropyrimidine-5-carbaldehyde (0.04 g, 40% yield) using 20% ethyl acetate-hexane as eluent. The product was characterized by 1HNMR (CDCl3, 300 MHz): δ 10.15 (s, 1H), 9.07 (s, 2H).

References

[1] Patent: WO2016/164703, 2016, A1. Location in patent: Page/Page column 60; 61

2-Chloropyrimidine-5-carbaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-Chloropyrimidine-5-carbaldehyde Suppliers

Belgium 1 Canada 1 China 137 Germany 1 India 1 United Kingdom 4 United States 12 Global 157
Shanghai Leiming Medical Technology Co., LTD
Tel
13761371720
Email
zhangleitao111@sina.com
Country
China
ProdList
475
Advantage
58
PharmaBlock Sciences (Nanjing), Inc.
Tel
4000255188
Email
marketing@pharmablock.com
Country
China
ProdList
9126
Advantage
58
SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
ProdList
918
Advantage
55
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
Chembon Pharmaceutical Co., Ltd.
Tel
028-84252981
Fax
+86-28-84252965
Email
sales@chembon.com.cn
Country
China
ProdList
850
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
SpringPharma Tech Co.,Ltd
Tel
+86-25-68710855, +86-25-68710897
Fax
025-68710856
Email
sales@springpharma.net
Country
China
ProdList
1261
Advantage
62
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
More
Less

View Lastest Price from 2-Chloropyrimidine-5-carbaldehyde manufacturers

R&D Scientific Inc.
Product
2-Chloropyrimidine-5-carboxyaldehyde 933702-55-7
Price
US $1250.00/g
Min. Order
1g
Purity
99 %
Supply Ability
500 Kg
Release date
2025-09-12
Shaanxi Dideu New Materials Co. Ltd
Product
2-Chloropyrimidine-5-carbaldehyde 933702-55-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-07-05
Shaanxi Dideu Medichem Co. Ltd
Product
2-Chloropyrimidine-5-carbaldehyde 933702-55-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2020-05-15

933702-55-7, 2-Chloropyrimidine-5-carbaldehydeRelated Search:

2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBONYL CHLORIDE 2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Pyrimidine-5-carboxaldehyde 2-Chloropyrimidine 4-CHLOROBENZYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE BENZYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE CYCLOPROPYLMETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE 2-CHLORO-N-(4-FLUORO-2-METHYLPHENYL)-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXAMIDE METHYL 3-[2-(([2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL]CARBONYL)AMINO)-4-(TRIFLUOROMETHYL)PHENOXY]THIOPHENE-2-CARBOXYLATE METHYL 2-(2-([2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL]CARBONYL)HYDRAZINO)-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE N5-PHENYL-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXAMIDE N5-(4-FLUOROPHENYL)-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXAMIDE N5-(3,5-DIFLUOROPHENYL)-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXAMIDE O1-([2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL]CARBONYL)-4-CHLOROBENZENE-1-CARBOHYDROXIMAMIDE N5-(2-FLUOROPHENYL)-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXAMIDE O1-([2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL]CARBONYL)-4-(TERT-BUTYL)BENZENE-1-CARBOHYDROXIMAMIDE

  • 2-Chloropyrimidine-5-carbaldehyde
  • 2-Chloropyrimidine-5-carb...
  • 2-Chloropyrimidine-5-carboxaldehyde
  • 2-ChloropyriMidine-5-carboxyaldehyde
  • 2-chloro-5-pyrimidinecarboxaldehyde
  • 5-Pyrimidinecarboxaldehyde, 2-chloro-
  • 2-Chloro-5-pyrimidinecarbaldehyde
  • 933702-55-7
  • Building Blocks
  • Pyrimidine