2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE

Uses Solubility

Product Name: 2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE
CAS No.: 50270-27-4
Chemical Name: 2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE
Synonyms: 2,4,6-Trichloropyrimidine-5-carboxaldehyde;SKL326;5-Formyl-2,4,6-trichloropyrimidine;6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE;2,4,6-TrichloropyriMidin-5-carbaldehyde;2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE;2,4,6-Trichloro-5-pyrimidinecarboxaldehyde;5-PyriMidinecarboxaldehyde,2,4,6-trichloro-;2,4,6-Trichloropyrimidine-5-carboxaldehyde,97%;2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE ISO 9001：2015 REACH
CBNumber: CB41009884
Molecular Formula: C5HCl3N2O
Formula Weight: 211.43
MOL File: 50270-27-4.mol

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2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE Property

Melting point:: 131-132℃
Boiling point:: 278.6±35.0 °C(Predicted)
Density: 1.713±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
pka: -8.75±0.39(Predicted)
form: Solid
color: White to brown
Water Solubility: Slightly soluble in water.
InChI: InChI=1S/C5HCl3N2O/c6-3-2(1-11)4(7)10-5(8)9-3/h1H
InChIKey: KVJIRFGNHAAUNQ-UHFFFAOYSA-N
SMILES: C1(Cl)=NC(Cl)=C(C=O)C(Cl)=N1

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Safety

RIDADR: UN2811
HazardClass: 6.1
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: T3100
Product name: 2,4,6-Trichloro-5-pyrimidinecarboxaldehyde
Purity: >98.0%(GC)
Packaging: 1g
Price: $38
Updated: 2025/07/31

TCI Chemical

Product number: T3100
Product name: 2,4,6-Trichloro-5-pyrimidinecarboxaldehyde
Purity: >98.0%(GC)
Packaging: 5g
Price: $113
Updated: 2025/07/31

TRC

Product number: T775025
Product name: 2,4,6-Trichloro-5-pyrimidinecarboxaldehyde
Packaging: 5g
Price: $85
Updated: 2021/12/16

Matrix Scientific

Product number: 072873
Product name: 2,4,6-Trichloropyrimidine-5-carbaldehyde
Purity: 95+%
Packaging: 5g
Price: $39
Updated: 2021/12/16

Apolloscientific

Product number: OR17605
Product name: 2,4,6-Trichloropyrimidine-5-carboxaldehyde
Packaging: 5g
Price: $45
Updated: 2021/12/16

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2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE Chemical Properties,Usage,Production

Uses

2,4,6-Trichloro-5-pyrimidinecarboxaldehyde is a useful reagent for organic synthesis.

Solubility

2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE is slightly soluble in water.

Uses

2,4,6-Trichloro-5-pyrimidinecarboxaldehyde is a useful reagent for organic synthesis.

Synthesis

68-12-2

67-52-7

50270-27-4

1. Pyrimidine-2,4,6-triol (10.0 g, 78.2 mmol) was dissolved with N,N-dimethylformamide (12 mL) in phosphorus trichloride (10 vol. eq.) and heated to reflux for 15 h. 2. Upon completion of the reaction, the excess of phosphorus trichloride was removed by distillation under reduced pressure. 3. The residue of the reaction was slowly poured into crushed ice and precipitated as a solid. 4. The solid product was collected by filtration and washed with cold water. The solid product was collected by filtration and washed with cold water to give 2,4,6-trichloropyrimidine-5-carboxaldehyde (8.0 g, 47% yield) as a yellow solid. 5. The crude product did not need to be further purified, and could be used in the subsequent reaction directly.

References

[1] Angewandte Chemie - International Edition, 2006, vol. 45, # 43, p. 7262 - 7265
[2] Patent: WO2012/103297, 2012, A1. Location in patent: Page/Page column 84-85
[3] Patent: WO2017/12576, 2017, A1. Location in patent: Page/Page column 197
[4] Patent: WO2011/14535, 2011, A1. Location in patent: Page/Page column 100
[5] Patent: WO2004/18435, 2004, A1. Location in patent: Page 55-56

2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE Suppliers

China 218 China Hong Kong 1 India 14 Japan 1 United Kingdom 3 United States 20 Global 257

Nanjing Pope Bio-tech R&D Co., Ltd

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View Lastest Price from 2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE 50270-27-4
Price: US $100.00-50.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-11-12

Dideu Industries Group Limited

Product: 2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE 50270-27-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons
Release date: 2022-02-09

Career Henan Chemical Co

Product: 2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE 50270-27-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-24

50270-27-4, 2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDERelated Search:

2-Chloro-4,6-dimethylpyrimidine 4,6-Dimethyl-2-mercaptopyrimidine 2-Methylsulfonyl-4,6-dimethoxypyrimidine 2,4-Dichloro-5-fluoropyrimidine 4,6-Dichloro-2-(methylthio)pyrimidine 2-MERCAPTO-4-METHYLPYRIMIDINE HYDROCHLORIDE 2-Amino-4,6-bis(difluoromethoxy)pyrimidine 2-Chloro-4,6-dimethoxypyrimidine 2-Hydroxy-4-methylpyrimidine hydrochloride 2-Amino-4-methoxypyrimidine 2,4,6-Trichloro-5-methylpyrimidine 2-Chloropyrimidine-5-carbaldehyde 2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE 2,4,6-Trichloropyrimidine 2,4-Dichloro-5-methylpyrimidine 4,6-Dichloro-5-pyrimidinecarbaldehyde 2,4,6-TRICHLOROPYRIMIDINE-5-CARBOXYLIC ACID 5-Pyrimidinecarboxaldehyde, 2,4-dichloro-

2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE

2,4,6-Trichloro-5-pyrimidinecarboxaldehyde

2,4,6-Trichloropyrimidine-5-carboxaldehyde

5-Formyl-2,4,6-trichloropyrimidine

2,4,6-TrichloropyriMidin-5-carbaldehyde

5-PyriMidinecarboxaldehyde,2,4,6-trichloro-

2,4,6-Trichloropyrimidine-5-carboxaldehyde,97%

2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE ISO 9001：2015 REACH

6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE

SKL326

50270-27-4

Heterocycle-Pyrimidine series

pharmacetical

Pyrimidine