2,4-Dichloro-5-fluoropyrimidine

Product Name: 2,4-Dichloro-5-fluoropyrimidine
CAS No.: 2927-71-1
Chemical Name: 2,4-Dichloro-5-fluoropyrimidine
Synonyms: 5-FLUORO-2,4-DICHLOROPYRIMIDINE;oro-5-fL;NSC 70442;uoropyrimidine;CHEMPACIFIC 37950;Fluorouracil Impurity 9;2,6-DICHLORO-5-FLUORORACIL;2,4-Dichloro-5-fluorouracil;4-Dichloro-5-fluoropyriMidine;2,4-dichloro5-fluropyrimidine
CBNumber: CB2683700
Molecular Formula: C4HCl2FN2
Formula Weight: 166.97
MOL File: 2927-71-1.mol

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2,4-Dichloro-5-fluoropyrimidine Property

Melting point:: 37-41 °C (lit.)
Boiling point:: 80 °C / 16mmHg
Density: 1.605±0.06 g/cm3(Predicted)
Flash point:: 223 °F
storage temp.: Inert atmosphere,2-8°C
solubility: soluble in Chloroform, Methanol
pka: -3.96±0.29(Predicted)
form: Powder or Crystalline Powder or Low Melting Solid
color: White to pale brown
Sensitive: Moisture Sensitive
InChI: InChI=1S/C4HCl2FN2/c5-3-2(7)1-8-4(6)9-3/h1H
InChIKey: WHPFEQUEHBULBW-UHFFFAOYSA-N
SMILES: C1(Cl)=NC=C(F)C(Cl)=N1
CAS DataBase Reference: 2927-71-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,C
Risk Statements: 36/37/38-34-22
Safety Statements: 26-36-37/39-45-36/37/39
RIDADR: 3261
WGK Germany: 3
Hazard Note: Irritant
HazardClass: 8
PackingGroup: Ⅲ
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 653233
Product name: 2,4-Dichloro-5-fluoropyrimidine
Purity: 97%
Packaging: 1g
Price: $32.1
Updated: 2024/03/01

TCI Chemical

Product number: D3374
Product name: 2,4-Dichloro-5-fluoropyrimidine
Purity: >98.0%(GC)
Packaging: 5g
Price: $20
Updated: 2024/03/01

TCI Chemical

Product number: D3374
Product name: 2,4-Dichloro-5-fluoropyrimidine
Purity: >98.0%(GC)
Packaging: 25g
Price: $78
Updated: 2024/03/01

Alfa Aesar

Product number: H26288
Product name: 5-Fluoro-2,4-dichloropyrimidine, 98%
Packaging: 5g
Price: $58.6
Updated: 2021/12/16

Alfa Aesar

Product number: H26288
Product name: 5-Fluoro-2,4-dichloropyrimidine, 98%
Packaging: 1g
Price: $21.1
Updated: 2021/12/16

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2,4-Dichloro-5-fluoropyrimidine Chemical Properties,Usage,Production

Chemical Properties

2,4-Dichloro-5-fluoropyrimidine is Yellow to Orange Crystalline Solid

Uses

2,4-Dichloro-5-fluoropyrimidine is used in the synthesis of two glucuronic derivatives of 5-fluorouracil as neoplasm inhibitors. It is used in the synthesis of two glucuronic derivatives of 5-fluorouracil as neoplasm inhibitors.

Uses

2,4-Dichloro-5-fluoropyrimidine can be used as a starting material to synthesize:

5-fluoropyrimidine-2-carboxamides and 5-fluoropyrimidine-4-carboxamides as potential kinase inhibitors.
A series of 2,4-diamino-5-fluoropyrimidine derivatives as potential protein kinase Cθ inhibitors.
2,4-Bisanilinopyrimidine derivatives as potential aurora kinases inhibitors.
5-fluoro-N,N-bis(4-methoxyphenyl)-2,4-pyrimidinediamine by reacting with p-methoxy aniline in the presence of DIPEA.
2-chloro-5-fluoro-4-(4-fluorophenyl)pyrimidine by Suzuki coupling reaction in the presence of (4-fluorophenyl)boronic acid triphenylphosphine, and palladium(II) acetate catalyst.
5-fluoro-2-(piperidin-4-yloxy)pyrimidin-4-amine, a scaffold, which is used in the preparation of potent deoxycytidine kinase inhibitors.

Flammability and Explosibility

Not classified

2,4-Dichloro-5-fluoropyrimidine Preparation Products And Raw materials

Raw materials

N,N-Dimethylaniline 5-Fluorouracil

Preparation Products

5-Fluorocytosine

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2,4-Dichloro-5-fluoropyrimidine Suppliers

Americas 1 Canada 2 China 387 Europe 3 France 1 Germany 7 India 13 Japan 2 Russia 1 Switzerland 2 Ukraine 1 United Kingdom 22 United States 56 Global 498

Hangzhou Chemtrue Bio-Tech Co.,Ltd.

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J & K SCIENTIFIC LTD.

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View Lastest Price from 2,4-Dichloro-5-fluoropyrimidine manufacturers

Hebei Chuanghai Biotechnology Co,.LTD

Product: 2,4-Dichloro-5-fluoropyrimidine 2927-71-1
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-21

Shaanxi Dideu Medichem Co. Ltd

Product: 2,4-Dichloro-5-fluoropyrimidine 2927-71-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-26

Henan Aochuang Chemical Co.,Ltd.

Product: 2,4-Dichloro-5-fluoropyrimidine 2927-71-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-28

2927-71-1, 2,4-Dichloro-5-fluoropyrimidineRelated Search:

4-Bromo-2,6-difluorobenzoic acid 2,4-Dichloropyrimidine 5-Fluoropyrimidine Fluorocytosine 2-Chloro-5-fluoropyrimidine 2,4-Dichloro-5-methylpyrimidine Dichlorofluoroethane 4,6-Dichloro-5-fluoropyrimidine FMOC-D-3-Trifluoromethylphe 2-Fluoro-3,5-dichloropyridine 2,4-DICHLORO-6-ETHYL-5-FLUOROPYRIMIDINE 3,5-DICHLORO-4-FLUOROPYRIDINE 2-AMINO-4,6-DICHLORO-5-FLUOROPYRIMIDINE 2,4-DICHLORO-6-FLUOROPYRIMIDINE 2,4,6-TRICHLORO-5-FLUOROPYRIMIDINE Pyrimidine, 4-chloro-5-fluoro- (9CI) 2,4-Dichloro-5-fluoropyrimidine 2,4-dichloro-5-fluoro-6-methylpyrimidine

CHEMPACIFIC 37950

5-FLUORO-2,4-DICHLOROPYRIMIDINE

2,4-DICHLORO-5-FLUOROPYRIMIDINE

2,4-Dichloro-5-fluorouracil

5-Fluoro-2,4-dichloropyrimdine

2,6-DICHLORO-5-FLUORORACIL

2,4-Dichloro-5-Fluoropyrimidin

2,4-Dichloro-5-fluoropyrimidine99%

2,4-Dichloro-5-fluoropyrimidine ,98%

2,4-Dicloro-5-fluoro pyrimidin

2,4-Dichloro-5-fluoropyrimidine (Abemaciclib Mesylate)

oro-5-fL

uoropyrimidine

4-Dichloro-5-fluoropyriMidine

2,4-Dichloro-5-fluorpyriMidine

2,4-Dichloro-5-fluoro-1,3-diazine

PyriMidine, 2,4-dichloro-5-fluoro-

4-(2-vinyl-1,3-dioxolan-4-yl)butan-1-ol

2,6-Dichloro-5-fluoropyriMidine

NSC 70442

2,4-two chloro-5- fluorouracil

5-Fluoro-2,4-dichloropyrimidine,98%

Pyrimidine, 5-fluoro-2,4-dichloro-

5-fluoro-2,4-dichloropirimidine

2,4-Dichloro-5-fluoropyrimidine&gt

2,4-Dichloro-5-fluoropyrimidine ISO 9001：2015 REACH

2,4-dichloro5-fluropyrimidine

TIANFU CHEM 2,4-Dichloro-5-fluoropyrimidine

2,4-Dichloro-5-fluoropyrimidine?New

Fluorouracil Impurity 9

2927-71-1

2927-71-7

C4HCl2FN2

C4HCl2FN2O2

C4HCI2FN2

C4HN2Cl2F

Building Blocks

Heterocyclic Building Blocks

Halogenated Heterocycles

Pyrimidines

Fluorine series

Aromatics

Bases & Related Reagents

Nucleotides

Pyrazines, Pyrimidines & Pyridazines

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Pyrimidines

PyrimidinesHeterocyclic Building Blocks

Building Blocks

Fluorinated

Nucleotides and Nucleosides

Pyridines, Pyrimidines, Purines and Pteredines

pharmacetical

Halides

Pyrazines, Pyrimidines & Pyridazines

Pyrimidine