ChemicalBook > CAS DataBase List > 2,4-Dichloro-5-fluoropyrimidine

2,4-Dichloro-5-fluoropyrimidine

Product Name
2,4-Dichloro-5-fluoropyrimidine
CAS No.
2927-71-1
Chemical Name
2,4-Dichloro-5-fluoropyrimidine
Synonyms
5-FLUORO-2,4-DICHLOROPYRIMIDINE;oro-5-fL;NSC 70442;uoropyrimidine;CHEMPACIFIC 37950;Fluorouracil Impurity 9;2,6-DICHLORO-5-FLUORORACIL;2,4-Dichloro-5-fluorouracil;4-Dichloro-5-fluoropyriMidine;2,4-dichloro5-fluropyrimidine
CBNumber
CB2683700
Molecular Formula
C4HCl2FN2
Formula Weight
166.97
MOL File
2927-71-1.mol
More
Less

2,4-Dichloro-5-fluoropyrimidine Property

Melting point:
37-41 °C (lit.)
Boiling point:
80 °C / 16mmHg
Density 
1.605±0.06 g/cm3(Predicted)
Flash point:
223 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
soluble in Chloroform, Methanol
pka
-3.96±0.29(Predicted)
form 
Powder or Crystalline Powder or Low Melting Solid
color 
White to pale brown
Sensitive 
Moisture Sensitive
InChI
InChI=1S/C4HCl2FN2/c5-3-2(7)1-8-4(6)9-3/h1H
InChIKey
WHPFEQUEHBULBW-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=C(F)C(Cl)=N1
CAS DataBase Reference
2927-71-1(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi,C
Risk Statements 
36/37/38-34-22
Safety Statements 
26-36-37/39-45-36/37/39
RIDADR 
3261
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
8
PackingGroup 
Ⅲ
HS Code 
29335990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
653233
Product name
2,4-Dichloro-5-fluoropyrimidine
Purity
97%
Packaging
1g
Price
$32.1
Updated
2024/03/01
TCI Chemical
Product number
D3374
Product name
2,4-Dichloro-5-fluoropyrimidine
Purity
>98.0%(GC)
Packaging
5g
Price
$20
Updated
2024/03/01
TCI Chemical
Product number
D3374
Product name
2,4-Dichloro-5-fluoropyrimidine
Purity
>98.0%(GC)
Packaging
25g
Price
$78
Updated
2024/03/01
Alfa Aesar
Product number
H26288
Product name
5-Fluoro-2,4-dichloropyrimidine, 98%
Packaging
5g
Price
$58.6
Updated
2021/12/16
Alfa Aesar
Product number
H26288
Product name
5-Fluoro-2,4-dichloropyrimidine, 98%
Packaging
1g
Price
$21.1
Updated
2021/12/16
More
Less

2,4-Dichloro-5-fluoropyrimidine Chemical Properties,Usage,Production

Chemical Properties

2,4-Dichloro-5-fluoropyrimidine is Yellow to Orange Crystalline Solid

Uses

2,4-Dichloro-5-fluoropyrimidine is used in the synthesis of two glucuronic derivatives of 5-fluorouracil as neoplasm inhibitors. It is used in the synthesis of two glucuronic derivatives of 5-fluorouracil as neoplasm inhibitors.

Uses

2,4-Dichloro-5-fluoropyrimidine can be used as a starting material to synthesize:

  • 5-fluoropyrimidine-2-carboxamides and 5-fluoropyrimidine-4-carboxamides as potential kinase inhibitors.
  • A series of 2,4-diamino-5-fluoropyrimidine derivatives as potential protein kinase Cθ inhibitors.
  • 2,4-Bisanilinopyrimidine derivatives as potential aurora kinases inhibitors.
  • 5-fluoro-N,N-bis(4-methoxyphenyl)-2,4-pyrimidinediamine by reacting with p-methoxy aniline in the presence of DIPEA.
  • 2-chloro-5-fluoro-4-(4-fluorophenyl)pyrimidine by Suzuki coupling reaction in the presence of (4-fluorophenyl)boronic acid triphenylphosphine, and palladium(II) acetate catalyst.
  • 5-fluoro-2-(piperidin-4-yloxy)pyrimidin-4-amine, a scaffold, which is used in the preparation of potent deoxycytidine kinase inhibitors.

Flammability and Explosibility

Not classified

2,4-Dichloro-5-fluoropyrimidine Preparation Products And Raw materials

Raw materials

N,N-Dimethylaniline 5-Fluorouracil

Preparation Products

5-Fluorocytosine
More
Less

2,4-Dichloro-5-fluoropyrimidine Suppliers

Americas 1 Canada 2 China 387 Europe 3 France 1 Germany 7 India 13 Japan 2 Russia 1 Switzerland 2 Ukraine 1 United Kingdom 22 United States 56 Global 498
Hangzhou Chemtrue Bio-Tech Co.,Ltd.
Tel
0571-86828652 18857119830
Fax
0571-83522824
Email
sales@chemtrue-bio.com
Country
China
ProdList
322
Advantage
58
China Synchem Technology Co.,Ltd.
Tel
+86-0552-4929304 +86-18055277008
Fax
+86-552-4928800
Email
sales@cnsynchem.com
Country
China
ProdList
57
Advantage
65
Jinan XuanDe Chemical Co., Ltd.
Tel
0531-88803958; 18866891188
Fax
0531-82777287
Email
zhaojiangxia@shiningpharm.com
Country
China
ProdList
275
Advantage
58
Ningbo Zhenlei Chemical Co.,ltd.
Tel
0576-88808091 13958565781
Fax
+0576-88203603
Email
shuang.lin@zhenleichem.com
Country
China
ProdList
89
Advantage
58
Jiangsu Zhongyuan Chemicals Co.,Ltd.
Tel
0513-84539538 13817775327
Email
jinjing860329@163.com
Country
China
ProdList
19
Advantage
58
Hubei Dongcao Chemical Technology Co., Ltd
Tel
027-83261126 18971318572
Email
2969475037@qq.com
Country
China
ProdList
5000
Advantage
58
Beihua Chemical (Shandong) Co., LTD
Tel
0531-68653689 13127106931
Email
1720760574@qq.com
Country
China
ProdList
54
Advantage
58
Changzhou Liren Medical Technology Co. Ltd.
Tel
0519-85859058 13915836899
Email
2078957504@qq.com
Country
China
ProdList
235
Advantage
58
Shandong Xuanshuo Pharmaceutical Technology Co. LTD
Tel
15269103900
Email
suchangzhou@shiningpharm.com
Country
China
ProdList
262
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Nanjing Habo Medical Technology Co., Ltd.
Tel
025-85760892 13376090521
Fax
025-85766769
Email
sales@habotech.com
Country
China
ProdList
979
Advantage
60
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19172
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
shanghai Rainbow MediTech.Co.Ltd.
Tel
21-021-64968085,64968086-5815,5812 13918693646
Fax
+86 21 64968087
Email
bd@rainbowpharma.cn
Country
China
ProdList
965
Advantage
65
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
ChemShuttle, Inc.
Tel
0510-83588313-802 18800520310;
Email
sales@chemshuttle.com
Country
China
ProdList
2996
Advantage
62
SpringPharma Tech Co.,Ltd
Tel
+86-25-68710855, +86-25-68710897
Fax
025-68710856
Email
sales@springpharma.net
Country
China
ProdList
1261
Advantage
62
Wuhan Arike Technology Co., Ltd.
Tel
027- 51832457 94518350
Fax
E-Mail Inquiry
Country
China
ProdList
746
Advantage
62
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
021-51613915-820 13611835272
Fax
021 51613951
Email
mmwang@sunwaypharm.cn
Country
China
ProdList
9734
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4552
Advantage
62
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
9387
Advantage
52
Sci General Material & Chemical Ltd
Tel
21-58388037 13472507714
Fax
0086-21-56829747 Company QQ: 1589045147
Email
1589045147@qq.com
Country
China
ProdList
728
Advantage
55
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2872
Advantage
58
Anhui Shite Pharmaceutical Technology Co., LTD
Tel
0555-8228058 13621628489
Fax
0512-63261912
Email
sales1@stepuppharm.com
Country
China
ProdList
229
Advantage
55
Synthetics China Co.,Ltd
Tel
0512-65218020; 18261037325
Email
ivy.shen@pharmsyn.com
Country
China
ProdList
108
Advantage
60
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9459
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
More
Less

View Lastest Price from 2,4-Dichloro-5-fluoropyrimidine manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
2,4-Dichloro-5-fluoropyrimidine 2927-71-1
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-21
Shaanxi Dideu Medichem Co. Ltd
Product
2,4-Dichloro-5-fluoropyrimidine 2927-71-1
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-26
Henan Aochuang Chemical Co.,Ltd.
Product
2,4-Dichloro-5-fluoropyrimidine 2927-71-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-28

2927-71-1, 2,4-Dichloro-5-fluoropyrimidineRelated Search:

4-Bromo-2,6-difluorobenzoic acid 2,4-Dichloropyrimidine 5-Fluoropyrimidine Fluorocytosine 2-Chloro-5-fluoropyrimidine 2,4-Dichloro-5-methylpyrimidine Dichlorofluoroethane 4,6-Dichloro-5-fluoropyrimidine FMOC-D-3-Trifluoromethylphe 2-Fluoro-3,5-dichloropyridine 2,4-DICHLORO-6-ETHYL-5-FLUOROPYRIMIDINE 3,5-DICHLORO-4-FLUOROPYRIDINE 2-AMINO-4,6-DICHLORO-5-FLUOROPYRIMIDINE 2,4-DICHLORO-6-FLUOROPYRIMIDINE 2,4,6-TRICHLORO-5-FLUOROPYRIMIDINE Pyrimidine, 4-chloro-5-fluoro- (9CI) 2,4-Dichloro-5-fluoropyrimidine 2,4-dichloro-5-fluoro-6-methylpyrimidine

  • CHEMPACIFIC 37950
  • 5-FLUORO-2,4-DICHLOROPYRIMIDINE
  • 2,4-DICHLORO-5-FLUOROPYRIMIDINE
  • 2,4-Dichloro-5-fluorouracil
  • 5-Fluoro-2,4-dichloropyrimdine
  • 2,6-DICHLORO-5-FLUORORACIL
  • 2,4-Dichloro-5-Fluoropyrimidin
  • 2,4-Dichloro-5-fluoropyrimidine99%
  • 2,4-Dichloro-5-fluoropyrimidine ,98%
  • 2,4-Dicloro-5-fluoro pyrimidin
  • 2,4-Dichloro-5-fluoropyrimidine (Abemaciclib Mesylate)
  • oro-5-fL
  • uoropyrimidine
  • 4-Dichloro-5-fluoropyriMidine
  • 2,4-Dichloro-5-fluorpyriMidine
  • 2,4-Dichloro-5-fluoro-1,3-diazine
  • PyriMidine, 2,4-dichloro-5-fluoro-
  • 4-(2-vinyl-1,3-dioxolan-4-yl)butan-1-ol
  • 2,6-Dichloro-5-fluoropyriMidine
  • NSC 70442
  • 2,4-two chloro-5- fluorouracil
  • 5-Fluoro-2,4-dichloropyrimidine,98%
  • Pyrimidine, 5-fluoro-2,4-dichloro-
  • 5-fluoro-2,4-dichloropirimidine
  • 2,4-Dichloro-5-fluoropyrimidine&gt
  • 2,4-Dichloro-5-fluoropyrimidine ISO 9001：2015 REACH
  • 2,4-dichloro5-fluropyrimidine
  • TIANFU CHEM 2,4-Dichloro-5-fluoropyrimidine
  • 2,4-Dichloro-5-fluoropyrimidine?New
  • Fluorouracil Impurity 9
  • 2927-71-1
  • 2927-71-7
  • C4HCl2FN2
  • C4HCl2FN2O2
  • C4HCI2FN2
  • C4HN2Cl2F
  • Building Blocks
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Pyrimidines
  • Fluorine series
  • Aromatics
  • Bases & Related Reagents
  • Nucleotides
  • Pyrazines, Pyrimidines & Pyridazines
  • Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyrimidines
  • PyrimidinesHeterocyclic Building Blocks
  • Building Blocks
  • Fluorinated
  • Nucleotides and Nucleosides
  • Pyridines, Pyrimidines, Purines and Pteredines
  • pharmacetical
  • Halides
  • Pyrazines, Pyrimidines & Pyridazines
  • Pyrimidine