ChemicalBook > CAS DataBase List > 2,4-Dichloro-5-fluoropyrimidine
2,4-Dichloro-5-fluoropyrimidine
- Product Name
- 2,4-Dichloro-5-fluoropyrimidine
- CAS No.
- 2927-71-1
- Chemical Name
- 2,4-Dichloro-5-fluoropyrimidine
- Synonyms
- 5-FLUORO-2,4-DICHLOROPYRIMIDINE;oro-5-fL;NSC 70442;uoropyrimidine;CHEMPACIFIC 37950;Fluorouracil Impurity 9;2,6-DICHLORO-5-FLUORORACIL;2,4-Dichloro-5-fluorouracil;4-Dichloro-5-fluoropyriMidine;2,4-dichloro5-fluropyrimidine
- CBNumber
- CB2683700
- Molecular Formula
- C4HCl2FN2
- Formula Weight
- 166.97
- MOL File
- 2927-71-1.mol
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2,4-Dichloro-5-fluoropyrimidine Property
- Melting point:
- 37-41 °C (lit.)
- Boiling point:
- 80 °C / 16mmHg
- Density
- 1.605±0.06 g/cm3(Predicted)
- Flash point:
- 223 °F
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- soluble in Chloroform, Methanol
- pka
- -3.96±0.29(Predicted)
- form
- Powder or Crystalline Powder or Low Melting Solid
- color
- White to pale brown
- Sensitive
- Moisture Sensitive
- InChI
- InChI=1S/C4HCl2FN2/c5-3-2(7)1-8-4(6)9-3/h1H
- InChIKey
- WHPFEQUEHBULBW-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC=C(F)C(Cl)=N1
- CAS DataBase Reference
- 2927-71-1(CAS DataBase Reference)
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Safety
- Hazard Codes
- Xi,C
- Risk Statements
- 36/37/38-34-22
- Safety Statements
- 26-36-37/39-45-36/37/39
- RIDADR
- 3261
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 8
- PackingGroup
- Ⅲ
- HS Code
- 29335990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 653233
- Product name
- 2,4-Dichloro-5-fluoropyrimidine
- Purity
- 97%
- Packaging
- 1g
- Price
- $32.1
- Updated
- 2024/03/01
TCI Chemical
- Product number
- D3374
- Product name
- 2,4-Dichloro-5-fluoropyrimidine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $20
- Updated
- 2024/03/01
TCI Chemical
- Product number
- D3374
- Product name
- 2,4-Dichloro-5-fluoropyrimidine
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $78
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- H26288
- Product name
- 5-Fluoro-2,4-dichloropyrimidine, 98%
- Packaging
- 5g
- Price
- $58.6
- Updated
- 2021/12/16
Alfa Aesar
- Product number
- H26288
- Product name
- 5-Fluoro-2,4-dichloropyrimidine, 98%
- Packaging
- 1g
- Price
- $21.1
- Updated
- 2021/12/16
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2,4-Dichloro-5-fluoropyrimidine Chemical Properties,Usage,Production
Chemical Properties
2,4-Dichloro-5-fluoropyrimidine is Yellow to Orange Crystalline Solid
Uses
2,4-Dichloro-5-fluoropyrimidine is used in the synthesis of two glucuronic derivatives of 5-fluorouracil as neoplasm inhibitors. It is used in the synthesis of two glucuronic derivatives of 5-fluorouracil as neoplasm inhibitors.
Uses
2,4-Dichloro-5-fluoropyrimidine can be used as a starting material to synthesize:
- 5-fluoropyrimidine-2-carboxamides and 5-fluoropyrimidine-4-carboxamides as potential kinase inhibitors.
- A series of 2,4-diamino-5-fluoropyrimidine derivatives as potential protein kinase Cθ inhibitors.
- 2,4-Bisanilinopyrimidine derivatives as potential aurora kinases inhibitors.
- 5-fluoro-N,N-bis(4-methoxyphenyl)-2,4-pyrimidinediamine by reacting with p-methoxy aniline in the presence of DIPEA.
- 2-chloro-5-fluoro-4-(4-fluorophenyl)pyrimidine by Suzuki coupling reaction in the presence of (4-fluorophenyl)boronic acid triphenylphosphine, and palladium(II) acetate catalyst.
- 5-fluoro-2-(piperidin-4-yloxy)pyrimidin-4-amine, a scaffold, which is used in the preparation of potent deoxycytidine kinase inhibitors.
Flammability and Explosibility
Not classified
2,4-Dichloro-5-fluoropyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
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2,4-Dichloro-5-fluoropyrimidine Suppliers
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View Lastest Price from 2,4-Dichloro-5-fluoropyrimidine manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- 2,4-Dichloro-5-fluoropyrimidine 2927-71-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-26
Hebei Guanlang Biotechnology Co,.LTD
- Product
- 2,4-Dichloro-5-fluoropyrimidine 2927-71-1
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2023-06-13
Henan Aochuang Chemical Co.,Ltd.
- Product
- 2,4-Dichloro-5-fluoropyrimidine 2927-71-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-28
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