ChemicalBook > CAS DataBase List > 2-Chloropyrimidine-5-carbaldehyde

2-Chloropyrimidine-5-carbaldehyde

Product Name
2-Chloropyrimidine-5-carbaldehyde
CAS No.
933702-55-7
Chemical Name
2-Chloropyrimidine-5-carbaldehyde
Synonyms
2-Chloropyrimidine-5-carb...;2-Chloropyrimidine-5-carbaldehyde;2-Chloro-5-pyrimidinecarbaldehyde;2-Chloropyrimidine-5-carboxaldehyde;2-chloro-5-pyrimidinecarboxaldehyde;2-ChloropyriMidine-5-carboxyaldehyde;5-Pyrimidinecarboxaldehyde, 2-chloro-
CBNumber
CB01454938
Molecular Formula
C5H3ClN2O
Formula Weight
142.54
MOL File
933702-55-7.mol
More
Less

2-Chloropyrimidine-5-carbaldehyde Property

Boiling point:
318.2±15.0 °C(Predicted)
Density 
1.432
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-3.03±0.22(Predicted)
form 
Powder or Crystalline Powder
color 
White to yellow
InChI
InChI=1S/C5H3ClN2O/c6-5-7-1-4(3-9)2-8-5/h1-3H
InChIKey
LJYQVOPFBNMTKJ-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=C(C=O)C=N1
More
Less

Safety

HS Code 
29335990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
C596410
Product name
2-Chloropyrimidine-5-carbaldehyde
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
C596410
Product name
2-Chloropyrimidine-5-carbaldehyde
Packaging
500mg
Price
$200
Updated
2021/12/16
TRC
Product number
C596410
Product name
2-Chloropyrimidine-5-carbaldehyde
Packaging
50mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
4H15-5-19
Product name
2-Chloropyrimidine-5-carbaldehyde
Packaging
5G
Price
$500
Updated
2021/12/16
ChemScene
Product number
CS-0019369
Product name
2-Chloropyrimidine-5-carbaldehyde
Purity
99.77%
Packaging
10g
Price
$345
Updated
2021/12/16
More
Less

2-Chloropyrimidine-5-carbaldehyde Chemical Properties,Usage,Production

Uses

2-Chloropyrimidine-5-carbaldehyde is an important organic reagent that can be used as a building block for the synthesis of many organic compounds, such as 2-(Dimethylamino)pyrimidine-5-carbaldehyde, 2-Aminopyrimidine-5-carboxaldehyde and so on.

Synthesis

131467-06-6

933702-55-7

General procedure for the synthesis of 2-chloropyrimidine-5-carbaldehyde from 2-chloro-5-vinylpyrimidine: 2-chloro-5-vinylpyrimidine (0.1 g, 0.7 mmol) was dissolved in a mixed solvent of dioxane (1 mL) and water (1 mL) at room temperature, and 2,6-dimethylpyridine (0.188 g, 1.76 mmol), osmium tetroxide (3.5 mg 0.007 mmol) and sodium periodate (0.59 g, 2.81 mmol). The reaction mixture was stirred at room temperature for 2-3 hours. After completion of the reaction, the reaction was quenched with ethyl acetate and water. The organic layer was separated and washed sequentially with water and brine. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography to afford 2-chloropyrimidine-5-carbaldehyde (0.04 g, 40% yield) using 20% ethyl acetate-hexane as eluent. The product was characterized by 1HNMR (CDCl3, 300 MHz): δ 10.15 (s, 1H), 9.07 (s, 2H).

References

[1] Patent: WO2016/164703, 2016, A1. Location in patent: Page/Page column 60; 61

2-Chloropyrimidine-5-carbaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-Chloropyrimidine-5-carbaldehyde Suppliers

Belgium 1 Canada 1 China 137 Germany 1 India 1 United Kingdom 4 United States 12 Global 157
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
AOBChem
Tel
--
Fax
--
Email
sales@aobchem.com
Country
United States
ProdList
885
Advantage
58
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
More
Less

View Lastest Price from 2-Chloropyrimidine-5-carbaldehyde manufacturers

R&D Scientific Inc.
Product
2-Chloropyrimidine-5-carboxyaldehyde 933702-55-7
Price
US $1250.00/g
Min. Order
1g
Purity
99 %
Supply Ability
500 Kg
Release date
2025-09-12
Shaanxi Dideu New Materials Co. Ltd
Product
2-Chloropyrimidine-5-carbaldehyde 933702-55-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-07-05
Shaanxi Dideu Medichem Co. Ltd
Product
2-Chloropyrimidine-5-carbaldehyde 933702-55-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2020-05-15

933702-55-7, 2-Chloropyrimidine-5-carbaldehydeRelated Search:

2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBONYL CHLORIDE 2,4,6-TRICHLORO-PYRIMIDINE-5-CARBALDEHYDE ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Pyrimidine-5-carboxaldehyde 2-Chloropyrimidine 4-CHLOROBENZYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE BENZYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE CYCLOPROPYLMETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE 2-CHLORO-N-(4-FLUORO-2-METHYLPHENYL)-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXAMIDE METHYL 3-[2-(([2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL]CARBONYL)AMINO)-4-(TRIFLUOROMETHYL)PHENOXY]THIOPHENE-2-CARBOXYLATE METHYL 2-(2-([2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL]CARBONYL)HYDRAZINO)-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE N5-PHENYL-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXAMIDE N5-(4-FLUOROPHENYL)-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXAMIDE N5-(3,5-DIFLUOROPHENYL)-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXAMIDE O1-([2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL]CARBONYL)-4-CHLOROBENZENE-1-CARBOHYDROXIMAMIDE N5-(2-FLUOROPHENYL)-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXAMIDE O1-([2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL]CARBONYL)-4-(TERT-BUTYL)BENZENE-1-CARBOHYDROXIMAMIDE

  • 2-Chloropyrimidine-5-carbaldehyde
  • 2-Chloropyrimidine-5-carb...
  • 2-Chloropyrimidine-5-carboxaldehyde
  • 2-ChloropyriMidine-5-carboxyaldehyde
  • 2-chloro-5-pyrimidinecarboxaldehyde
  • 5-Pyrimidinecarboxaldehyde, 2-chloro-
  • 2-Chloro-5-pyrimidinecarbaldehyde
  • 933702-55-7
  • Building Blocks
  • Pyrimidine