N-CHLOROACETYL-2,6-DIETHYLANILINE Property

Melting point:

128-130°C

Boiling point:

369.2±42.0 °C(Predicted)

Density 

1.131±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

12.91±0.70(Predicted)

form 

Solid

color 

White to Off-White

BRN 

2111384

Stability:

Moisture Sensitive

CAS DataBase Reference

6967-29-9(CAS DataBase Reference)

EPA Substance Registry System

Acetamide, 2-chloro-N-(2,6-diethylphenyl)- (6967-29-9)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

HazardClass 

IRRITANT

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

N-CHLOROACETYL-2,6-DIETHYLANILINE Chemical Properties,Usage,Production

Uses

2-?Chloro-?(N-?2,?6-?diethyl phenyl)?acetamide is a reagent used in the synthesis of novel inhibitors of signal transducer and activator of the transcription (STAT3) signalling pathway which is used in the treatment of cancers.

Definition

ChEBI: N-(2,6-diethylphenyl)-2-chloroacetamide is an aromatic amide obtained by formal condensation of the carboxy group of chloroacetic acid with the amnio group of 2,6-diethylaniline. It has a role as a bacterial xenobiotic metabolite, a human xenobiotic metabolite, a rat metabolite, a fungal xenobiotic metabolite, a genotoxin and a carcinogenic agent. It is an organochlorine compound and an aromatic amide. It is functionally related to a chloroacetic acid.