ChemicalBook > CAS DataBase List > 2,6-Diethylaniline

2,6-Diethylaniline

Product Name
2,6-Diethylaniline
CAS No.
579-66-8
Chemical Name
2,6-Diethylaniline
Synonyms
DEA;2,6-diethyl-anilin;Benzenamine, 2,6-diethyl-;2.6-Diethylani;DEA) 2,6-Diethy;AKOS BBS-00003623;2,6-DIETHYLANALINE;2,6-DIETHYLANILINE;Aniline, 2,6-diethyl-;2,6- twoethyl aniline
CBNumber
CB6259518
Molecular Formula
C10H15N
Formula Weight
149.23
MOL File
579-66-8.mol
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2,6-Diethylaniline Property

Melting point:
3-4 °C
Boiling point:
243 °C (lit.)
Density 
0.906 g/mL at 25 °C (lit.)
vapor pressure 
0.02 mm Hg ( 20 °C)
refractive index 
n20/D 1.545(lit.)
Flash point:
254 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
4.13±0.10(Predicted)
form 
Liquid
color 
Clear yellow to reddish-brown
Water Solubility 
0.67g/L(26.7 ºC)
Sensitive 
Air Sensitive
BRN 
1423626
Stability:
Air Sensitive
CAS DataBase Reference
579-66-8(CAS DataBase Reference)
NIST Chemistry Reference
Benzenamine, 2,6-diethyl-(579-66-8)
EPA Substance Registry System
2,6-Diethylaniline (579-66-8)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
23-24
RIDADR 
2810
WGK Germany 
2
RTECS 
BX3500000
8-9-23
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29214200
Hazardous Substances Data
579-66-8(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
149381
Product name
2,6-Diethylaniline
Purity
98%
Packaging
100ml
Price
$59.9
Updated
2024/03/01
TCI Chemical
Product number
D0476
Product name
2,6-Diethylaniline
Purity
>98.0%(GC)(T)
Packaging
25mL
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
D0476
Product name
2,6-Diethylaniline
Purity
>98.0%(GC)(T)
Packaging
100mL
Price
$30
Updated
2024/03/01
TRC
Product number
D443525
Product name
2,6-Diethylaniline
Packaging
1g
Price
$110
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD64331
Product name
2,6-Diethylaniline
Packaging
2g
Price
$114
Updated
2021/12/16
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2,6-Diethylaniline Chemical Properties,Usage,Production

Chemical Properties

Clear liquid

Uses

2,6-Diethylaniline is used as a reagent in the synthesis of herbicides, for instance Butachlor (B689925); a pre-emergent chloroacetanalide herbicide commonly used for weed control in rice as well as cotton, maize, wheat and other crops.

Production Methods

2,6-Diethylaniline is obtained in high yield when aniline is heated with ethylene at 200-300°C under high pressure in the presence of aluminum anilide (Northcott 1978).

General Description

The 2,6-diethylaniline complexes with iodine, as a sigma-acceptor, were studied spectrophotometrically in chloroform, dichloromethane and carbontetrachloride solutions. It is an intermediate for the production of alachlor, butachlor, metolachlor-herbicides, tiafentiurone-insecticide, carbodiimide and RIM-PUR.

Industrial uses

2,6-Diethylaniline is used in the synthesis of herbicides such as Nevirex G and butachlor (Vertesi and Miklos 1982; Lee et al 1982).

Metabolic pathway

Incubation of 2,6-diethylaniline (DEA) with NADPH- fortified rat liver microsomal enzymes produces 4- amino-3,5-diethylphenol (ADEP) as the major oxidation product. ADEP is shown to undergo further oxidation to 3,5-diethylbenzoquinone-4-imine (DEBQI), which is isolated as a minor metabolite during DEA oxidation.

Metabolism

Incubation of 2,6-diethylaniline with NADPH-fortified microsomes produced 4-amino-3,5-diethylphenol (ADEP) as the major oxidation product (Feng and Wratten 1987). ADEP underwent further oxidation to 3,5-diethyl-benzoquinone-4-imine which is isolated as a minor metabolite during 2,6-diethylaniline metabolism. 2,6-Diethylaniline is produced under aerobic soil conditions as a minor metabolite of the herbicide butachlor (Lee et al 1982). 2,6-Diethylaniline is degraded by the soil microorganism Chaetomium globosum to 2,6-diethylacetanilide and 2,6-diethyl-p-benzoquinone (Lee and Ryu 1982). 2,6-Diethylaniline was also very persistent towards biodegradation in pond water with and without sewage sludge inoculation (Lyons et al 1985).

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2,6-Diethylaniline Suppliers

Jiangsu Danhua Group Co. LTD.
Tel
0511-86522311
Email
wjj@danhua-group.com
Country
China
ProdList
1
Advantage
58
Shandong Xinxian Yingtai Chemical Co., Ltd
Tel
0635-7888358 15550585968
Email
sxythg@126.com
Country
China
ProdList
8
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19172
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
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View Lastest Price from 2,6-Diethylaniline manufacturers

Anhui Royal Chemical Co., Ltd.
Product
2,6-Diethylaniline 579-66-8
Price
US $100.00/KG
Min. Order
200KG
Purity
99%
Supply Ability
20ton
Release date
2018-10-30
Hebei Weibang Biotechnology Co., Ltd
Product
2,6-Diethylaniline 579-66-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-28
Hebei Yanxi Chemical Co., Ltd.
Product
2,6-Diethylaniline 579-66-8
Price
US $20.00-10.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-09-15

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