ChemicalBook > CAS DataBase List > TIN PROTOPORPHYRIN IX DICHLORIDE

TIN PROTOPORPHYRIN IX DICHLORIDE

Product Name
TIN PROTOPORPHYRIN IX DICHLORIDE
CAS No.
14325-05-4
Chemical Name
TIN PROTOPORPHYRIN IX DICHLORIDE
Synonyms
SnPPIX;Nsc267099;TINPROTOPORPHYRIN;Tin protoporphyrin I;tin protoporphyrin IX;TIN PROTOPORPHYRIN IX DICHLORIDE;Tin Protoporphyrin IX (chloride);Tinprotoporphyrin IX,Tin protoporphyrin IX;Tin Protoporphyrin IX dichloride (NSC 267099;Stannate(2-) dichloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid]
CBNumber
CB0148951
Molecular Formula
C34H36Cl2N4O4Sn
Formula Weight
754.29
MOL File
14325-05-4.mol
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TIN PROTOPORPHYRIN IX DICHLORIDE Property

storage temp. 
Store at RT
solubility 
Soluble to 25 mM in 1eq. NaOH and to 5 mM in DMSO
form 
Dark red to violet solid.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16375
Product name
Tin Protoporphyrin IX (chloride)
Packaging
5mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
16375
Product name
Tin Protoporphyrin IX (chloride)
Packaging
10mg
Price
$92
Updated
2024/03/01
Cayman Chemical
Product number
16375
Product name
Tin Protoporphyrin IX (chloride)
Packaging
25mg
Price
$216
Updated
2024/03/01
Cayman Chemical
Product number
16375
Product name
Tin Protoporphyrin IX (chloride)
Packaging
50mg
Price
$380
Updated
2024/03/01
Tocris
Product number
0747
Product name
TinprotoporphyrinIXdichloride
Packaging
10
Price
$129
Updated
2021/12/16
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TIN PROTOPORPHYRIN IX DICHLORIDE Chemical Properties,Usage,Production

Uses

Tin Protoporphyrin IX Dichloride is a selective inhibitor of heme oxygenase.

Uses

Heme oxygenase (HO) converts protoheme to biliverdin, which in turn is enzymatically metabolized to bilirubin . While HO-2 is constitutively expressed, HO-1 can be induced by its heme substrate as well as by heavy metals, oxidizing agents, and other environmental stresses. TIN PROTOPORPHYRIN IX DICHLORIDE(SnPPIX) is a synthetic heme analog that selectively inhibits HO-1 (Ki = 11 nM) over HO-2 (IC50 = 7.5 μM). It also weakly inhibits endothelial nitric oxide synthase and soluble guanylyl cyclase (IC50s = 35 and 30 nM, respectively). SnPPIX prevents hyperbilirubinemia in neonates by blocking HO-1 activity that increases postnatally. It is rapidly cleared from plasma and persists in certain tissues, including kidney, liver, and spleen. SnPPIX is commonly used as a tool to study the role of HO-1 activity in cells and in animals.[Cayman Chemical]

TIN PROTOPORPHYRIN IX DICHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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TIN PROTOPORPHYRIN IX DICHLORIDE Suppliers

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14325-05-4, TIN PROTOPORPHYRIN IX DICHLORIDERelated Search:


  • TIN PROTOPORPHYRIN IX DICHLORIDE
  • tin protoporphyrin IX
  • TINPROTOPORPHYRIN
  • Nsc267099
  • Stannate(2-) dichloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid]
  • Tin Protoporphyrin IX (chloride)
  • SnPPIX
  • Tin protoporphyrin I
  • Tin Protoporphyrin IX dichloride (NSC 267099
  • Tinprotoporphyrin IX,Tin protoporphyrin IX
  • 14325-05-4
  • C34H32Cl2N4O4Sn
  • Porphyrins