5-CHLOROSULFONYL-2-ETHOXYBENZOIC ACID
- Product Name
- 5-CHLOROSULFONYL-2-ETHOXYBENZOIC ACID
- CAS No.
- 200575-16-2
- Chemical Name
- 5-CHLOROSULFONYL-2-ETHOXYBENZOIC ACID
- Synonyms
- SKL364;Sparfloxacin int;5-CHLOROSULFONYL-2-ETHOXYBENZOIC ACID;5-Chlorosulfony)-2-ethoxybenzoic acid;Benzoic acid, 5-(chlorosulfonyl)-2-ethoxy-;200575-16-2 5-CHLOROSULFONYL-2-ETHOXYBENZOIC ACID
- CBNumber
- CB01492961
- Molecular Formula
- C9H9ClO5S
- Formula Weight
- 264.68
- MOL File
- 200575-16-2.mol
5-CHLOROSULFONYL-2-ETHOXYBENZOIC ACID Property
- Boiling point:
- 446.5±30.0 °C(Predicted)
- Density
- 1.477
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 3.01±0.10(Predicted)
- Appearance
- Light yellow to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- C433138
- Product name
- 5-(Chlorosulfonyl)-2-ethoxybenzoicAcid
- Packaging
- 500mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- HCH0060588
- Product name
- 5-(CHLOROSULFONYL)-2-ETHOXYBENZOIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $808.89
- Updated
- 2021/12/16
- Product number
- 0309AB
- Product name
- 5-(Chlorosulfonyl)-2-ethoxybenzoicacid
- Packaging
- 25g
- Price
- $988
- Updated
- 2021/12/16
- Product number
- HCH0060588
- Product name
- 5-(CHLOROSULFONYL)-2-ETHOXYBENZOIC ACID
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1147.43
- Updated
- 2021/12/16
- Product number
- HCH0060588
- Product name
- 5-(CHLOROSULFONYL)-2-ETHOXYBENZOIC ACID
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1421.65
- Updated
- 2021/12/16
5-CHLOROSULFONYL-2-ETHOXYBENZOIC ACID Chemical Properties,Usage,Production
Synthesis
134-11-2
200575-16-2
Example 1 Preparation of 5-chlorosulfonyl-2-ethoxybenzoic acid (II): in a 250 mL three-neck flask, 2-ethoxybenzoic acid (50 g, 0.30 mol) was slowly added dropwise to ice-bath cooled dichlorosulfoxide (22 mL). Under stirring conditions, dichlorosulfoxide (0.30 mol) and chlorosulfonic acid (82.6 mL, 1.24 mol) were added sequentially. The temperature of the reaction mixture needed to be strictly controlled not to exceed 25 °C during the reaction. After the reaction mixture was stirred continuously for 18 h at room temperature, it was slowly poured into ice water with stirring, at which time a white precipitate was generated. The reaction mixture was continued to be stirred for 1 h. Subsequently, filtration was carried out, the precipitate was washed with water, and finally dried under vacuum to give 64.4 g of the crude product (II) as a white solid in 81% yield with a melting point of 108-110 °C.
References
[1] Organic Process Research and Development, 2000, vol. 4, # 1, p. 17 - 22
[2] Patent: EP1400522, 2004, A1. Location in patent: Page 5
[3] Patent: US5955611, 1999, A
[4] Patent: US6723719, 2004, B1. Location in patent: Page column 63
[5] Patent: WO2017/85056, 2017, A1. Location in patent: Page/Page column 54; 55
5-CHLOROSULFONYL-2-ETHOXYBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
5-CHLOROSULFONYL-2-ETHOXYBENZOIC ACID Suppliers
- Tel
- --
- Fax
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- sales@ajchem.in
- Country
- India
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- 6100
- Advantage
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View Lastest Price from 5-CHLOROSULFONYL-2-ETHOXYBENZOIC ACID manufacturers
- Product
- 5-CHLOROSULFONYL-2-ETHOXYBENZOIC ACID 200575-16-2
- Price
- US $35.00-330.00/KG
- Min. Order
- 1KG
- Purity
- 0.98
- Supply Ability
- 20 tons
- Release date
- 2023-09-21