Lithium dodecyl sulfate
- Product Name
- Lithium dodecyl sulfate
- CAS No.
- 2044-56-6
- Chemical Name
- Lithium dodecyl sulfate
- Synonyms
- LDS;LITHIUM LAURYL SULPHATE;LiDS;hMAD;JV15;hSMAD;hMAD-3;hSMAD3;MAD homolog;Press-on Lids
- CBNumber
- CB0150488
- Molecular Formula
- C12H25LiO4S
- Formula Weight
- 272.33
- MOL File
- 2044-56-6.mol
Lithium dodecyl sulfate Property
- Boiling point:
- 199℃[at 101 325 Pa]
- Density
- 1.168[at 20℃]
- vapor pressure
- 6.5Pa at 20℃
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- H2O: 0.1 M at 20 °C, clear, colorless
- form
- Shiny Crystalline Flakes or Powder
- color
- White
- PH
- pH(0.25mol/l, 25℃) : 5.0～10.5
- Appearance
- White to Almost white powder to crystal.
- Water Solubility
- Soluble in water.
- BRN
- 5186718
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChI
- InChI=1S/C12H26O4S.Li/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
- InChIKey
- YFVGRULMIQXYNE-UHFFFAOYSA-M
- SMILES
- C(COS([O-])(=O)=O)CCCCCCCCCC.[Li+]
- CAS DataBase Reference
- 2044-56-6(CAS DataBase Reference)
- EPA Substance Registry System
- Sulfuric acid, monododecyl ester, lithium salt (2044-56-6)
- Absorption
- ≤0.05 at 260nm (3% solution)
≤0.05 at 280nm (3% solution)
Safety
- Hazard Codes
- Xi,C,F
- Risk Statements
- 36/37/38-34-20/21/22-15-14-11-41-37/38
- Safety Statements
- 26-36-45-43-36/37/39-16-7/8-3/7/9-39
- RIDADR
- UN1325 - class 4.1 - PG 3 - Flammable solids, organic, n.o.s., HI: all
- WGK Germany
- 3
- F
- 3
- TSCA
- Yes
- HazardClass
- 4.1
- HS Code
- 29209010
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H228Flammable solid
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- L4632
- Product name
- Lithium dodecyl sulfate
- Purity
- ≥98.5% (GC)
- Packaging
- 5g
- Price
- $57.78
- Updated
- 2025/07/31
- Product number
- L4632
- Product name
- Lithium dodecyl sulfate
- Purity
- ≥98.5% (GC)
- Packaging
- 25g
- Price
- $167.4
- Updated
- 2025/07/31
- Product number
- BR65643
- Product name
- BRAND<SUP>®</SUP> desiccator ′Novus′ lid with knob
- Purity
- nominal diameter × O.D. × H 250 mm × 320 mm × 115 mm, with knob lid
- Packaging
- 1 ea
- Price
- $173
- Updated
- 2025/07/31
- Product number
- BR65738
- Product name
- BRAND<SUP>®</SUP> desiccator ′Novus′ lid with socket NS 24/29
- Purity
- nominal diameter × O.D. × H 200 mm × 270 mm × 93 mm, joint: 24/29
- Packaging
- 1 ea
- Price
- $212
- Updated
- 2025/07/31
- Product number
- BR65631
- Product name
- BRAND<SUP>®</SUP> desiccator ′Novus′ lid with knob
- Purity
- nominal diameter × O.D. × H 150 mm × 215 mm × 78 mm, with knob lid
- Packaging
- 1 ea
- Price
- $155
- Updated
- 2025/07/31
Lithium dodecyl sulfate Chemical Properties,Usage,Production
Description
Lithium dodecyl sulfate (LDS) is an anionic detergent and surfactant that is frequently used in electrophoresis and chromatography. LDS may be substituted for sodium dodecyl sulfate (SDS) in electrophoresis under cold conditions. The use of LDS in micellar electrokinetic chromatography has been extensively studied. A report has been published on the partition equilibria of LDS between water and bilayer membranes. LDS has been utilized in protein electrophoresis and proteomics studies. The three-dimensional structure of the amyloid β-protein fragment 25-35 has been investigated in LDS micelles by two-dimensional 1HNMR. LDS has been used to induce changes in protein conformation.
Chemical Properties
Lithium dodecyl sulfate is a white, shiny crystalline powder or flake, soluble in organic solvents such as alcohols, ethers, and hydrocarbons, but only slightly soluble in water. It exhibits good thermal stability and remains stable at room temperature. As an anionic surfactant, it demonstrates excellent surface activity.
Uses
Lithium dodecyl sulfate has been used as a component of lysis buffer.
Uses
Anionic detergent that may be used in place of SDS for electrophoresis in cold conditions.
Flammability and Explosibility
Flammable
Purification Methods
Recrystallise this detergent twice from absolute EtOH and dry it under vacuum. Critical Micellar Concentration (CMC) in H2O is 8.77 x 10-3M. [Mukerjee et al. J Phys Chem 71 4166 1967, Mysels & Dulin J Colloid Sci 10 461 1955, Beilstein 1 IV 1847.]
Precautions
In general, autoclaved lauryl sulfate solutions undergo hydrolysis to yield lauryl alcohol, which precipitates from solution, and sulfuric acid, which decreases the solution pH. It is not advised to autoclave lauryl sulfate solutions.
References
[1] ELISABET FUGUET. Solute−Solvent Interactions in Micellar Electrokinetic Chromatography. 6. Optimization of the Selectivity of Lithium Dodecyl Sulfate−Lithium Perfluorooctanesulfonate Mixed Micellar Buffers[J]. Analytical Chemistry, 2002, 74 17: 4447-4455. DOI:10.1021/ac0201530.
[2] M D TRONE. Characterization of chemical selectivity in micellar electrokinetic chromatography. VI. Effects of surfactant counter-ion.[J]. Journal of Chromatography A, 2000, 888 1-2: 229-240. DOI:10.1016/s0021-9673(00)00515-x.
[3] GARY H. PERDEW Daniel P S Henry W Schaup. The use of a zwitterionic detergent in two-dimensional gel electrophoresis of trout liver microsomes[J]. Analytical biochemistry, 1983, 135 2: Pages 453-455. DOI:10.1016/0003-2697(83)90711-X.
[4] SHINJI KONDOU. Concentrated Lithium Dodecyl Sulfate Aqueous Electrolytes: Utilizing Self-Assembly and Interfacial Adsorption for Aqueous Li-ion Batteries[J]. ChemElectroChem, 2022, 9 20. DOI:10.1002/celc.202200870.
Lithium dodecyl sulfate Preparation Products And Raw materials
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View Lastest Price from Lithium dodecyl sulfate manufacturers
- Product
- Lithium dodecyl sulfate 2044-56-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99.52%
- Supply Ability
- 1000kg
- Release date
- 2025-07-25
- Product
- LITHIUM DODECYL SULFATE 2044-56-6
- Price
- US $5.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10000
- Release date
- 2024-08-14
- Product
- Lithium Dodecyl Sulfate 2044-56-6
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-10-24