8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL

Product Name: 8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL
CAS No.: 59108-43-9
Chemical Name: 8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL
Synonyms: BUTTPARK 91\04-55;8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL;8-broMo-2-(trifluoroMethyl)-4-quinolinone;4-Quinolinol, 8-bromo-2-(trifluoromethyl)-;2-Trifluoromethyl-4-hydroxy-8-bromoquinoline;8-BroMo-4-hydroxy-2-(trifluoroMethyl)quinoline;-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER;8-bromo-2-(trifluoromethyl)quinolin-4-ol, 95%, HC-6749;8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL ISO 9001：2015 REACH
CBNumber: CB0151243
Molecular Formula: C10H5BrF3NO
Formula Weight: 292.05
MOL File: 59108-43-9.mol

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8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL Property

Melting point:: 136 °C
Boiling point:: 354.6±37.0 °C(Predicted)
Density: 1.771±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
pka: 6.16±0.40(Predicted)
CAS DataBase Reference: 59108-43-9

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 075504
Product name: 8-Bromo-4-hydroxy-2-(trifluoromethyl)quinoline
Purity: 95+%
Packaging: 1g
Price: $231
Updated: 2021/12/16

AK Scientific

Product number: W7202
Product name: 8-Bromo-4-hydroxy-2-(trifluoromethyl)quinoline
Packaging: 10g
Price: $304
Updated: 2021/12/16

Matrix Scientific

Product number: 075504
Product name: 8-Bromo-4-hydroxy-2-(trifluoromethyl)quinoline
Purity: 95+%
Packaging: 5g
Price: $639
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0025421
Product name: 8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL
Purity: 95.00%
Packaging: 1G
Price: $831.6
Updated: 2021/12/16

Matrix Scientific

Product number: 075504
Product name: 8-Bromo-4-hydroxy-2-(trifluoromethyl)quinoline
Purity: 95+%
Packaging: 10g
Price: $929
Updated: 2021/12/16

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8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL Chemical Properties,Usage,Production

Synthesis

372-31-6

615-36-1

587885-87-8

Step 1: Ethyl trifluoroacetoacetate (10 g, 58.5 mmol) was slowly added dropwise to a mixture of o-bromoaniline (10.7 g, 58.5 mmol) and polyphosphoric acid (PPA, 40 g) at 100 °C for a controlled time of less than 15 min. After the dropwise addition, the reaction mixture was warmed up to 150 °C with continuous stirring for 12 hours. After completion of the reaction, it was cooled to room temperature and the reaction mixture was diluted with 10 wt% sodium hydroxide solution (160 mL). The precipitate was collected by filtration and the filtrate was acidified with concentrated hydrochloric acid. The precipitate was collected by filtration again and recrystallized with ethanol to give the target compound 140-3 (10.5 g, 62% yield) as a white solid. Mass spectrometry (ESI) analysis: C10H5BrF3NO [M + H]+ calculated value 292, measured value 292.

References

[1] European Journal of Organic Chemistry, 2003, # 8, p. 1576 - 1588
[2] Patent: EP3124482, 2017, A1. Location in patent: Paragraph 0281; 0282

8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL Preparation Products And Raw materials

Raw materials

Preparation Products

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8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL Suppliers

Belgium 1 China 59 Germany 1 India 1 United Kingdom 1 United States 6 Global 69

Alchem Pharmtech,Inc.

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Aladdin Scientific

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Synthonix Inc

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Combi-Blocks Inc.

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Matrix Scientific

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3B Scientific Corporation

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ProdList: 6718
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View Lastest Price from 8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL manufacturers

Honest Joy Holdings Limited

Product: 8-Bromo-2-(Trifluoromethyl)Quinolin-4-OL 59108-43-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.9%
Supply Ability: 100 tons
Release date: 2022-01-14

Career Henan Chemical Co

Product: 8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL 59108-43-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 10 tons
Release date: 2020-01-10

59108-43-9, 8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OLRelated Search:

8-Bromoquinoline 8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL 2-(TRIFLUOROMETHYL)-4-HYDROXYPYRIDINE 4-HYDROXY-8-BROMOQUINOLINE 4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE 8-BROMO-4-HYDROXY-2-METHYLQUINOLINE 2-TRIFLUOROMETHYLQUINOLINE

8-broMo-2-(trifluoroMethyl)-4-quinolinone

-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL

BUTTPARK 91\04-55

8-BroMo-4-hydroxy-2-(trifluoroMethyl)quinoline

2-Trifluoromethyl-4-hydroxy-8-bromoquinoline

4-Quinolinol, 8-bromo-2-(trifluoromethyl)-

8-BROMO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL ISO 9001：2015 REACH

8-bromo-2-(trifluoromethyl)quinolin-4-ol, 95%, HC-6749

59108-43-9