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2-Pyridinethiol 1-oxide

Product Name
2-Pyridinethiol 1-oxide
CAS No.
1121-31-9
Chemical Name
2-Pyridinethiol 1-oxide
Synonyms
2-MERCAPTOPYRIDINE N-OXIDE;Omadine;N-Hydroxy-2-thiopyridone;CPAMD4;FLJ17816;FLJ17822;Human C5 Protein;PYRIDINETHIOLOXIDE;ZINE PYRITHIONE 50 %;MercaptopyridineNoxide
CBNumber
CB0163604
Molecular Formula
C5H5NOS
Formula Weight
127.16
MOL File
1121-31-9.mol
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2-Pyridinethiol 1-oxide Property

Melting point:
69-72 °C (lit.)
Boiling point:
350.2±15.0 °C(Predicted)
Density 
1.255 (estimate)
refractive index 
1.5480 (estimate)
storage temp. 
Refrigerator
solubility 
Soluble in tris-hydrochloric acid.
form 
Powder, Crystals, and/or Chunks
pka
5.40±0.50(Predicted)
color 
Off-white to beige or yellow to yellow-greenish or grayish-green
Sensitive 
Air & Light Sensitive
Merck 
14,7994
BRN 
906983
Stability:
Stable. Incompatible with strong bases, strong oxidizing agents.
InChI
1S/C5H5NOS/c7-6-4-2-1-3-5(6)8/h1-4,8H
InChIKey
FGVVTMRZYROCTH-UHFFFAOYSA-N
SMILES
[O-][n+]1ccccc1S
CAS DataBase Reference
1121-31-9(CAS DataBase Reference)
NIST Chemistry Reference
2-Mercaptopyridine-n-oxide(1121-31-9)
EPA Substance Registry System
2-Pyridinethiol, 1-oxide (1121-31-9)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22-63-20/21/22
Safety Statements 
26-36-24/25-36/37-22
RIDADR 
2811
WGK Germany 
3
RTECS 
UT8999000
8-10-13-23
TSCA 
TSCA listed
HS Code 
29333990
Storage Class
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications
Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
188549
Product name
2-Mercaptopyridine N-oxide
Purity
99%
Packaging
5g
Price
$155
Updated
2026/04/30
Sigma-Aldrich
Product number
188549
Product name
2-Mercaptopyridine N-oxide
Purity
99%
Packaging
25g
Price
$502
Updated
2026/04/30
Sigma-Aldrich
Product number
SAB1303159
Product name
ANTI-C5 (N-TERM) antibody produced in rabbit
Purity
IgG fraction of antiserum, buffered aqueous solution
Packaging
400μL
Price
$427
Updated
2022/05/15
TCI Chemical
Product number
H0302
Product name
2-Mercaptopyridine N-Oxide
Purity
>95.0%(T)
Packaging
5g
Price
$43
Updated
2026/04/30
TCI Chemical
Product number
H0302
Product name
2-Mercaptopyridine N-Oxide
Purity
>95.0%(T)
Packaging
25g
Price
$121
Updated
2026/04/30
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2-Pyridinethiol 1-oxide Chemical Properties,Usage,Production

Chemical Properties

off-white powder

Uses

2-Mercaptopyridine N-oxide is used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures. It is used in the radical coupling of benzoyl derivatives of 2-deoxy-D-ribose, with heterocyclic bases to give C-nucleosides. It acts as a ligand and form coordination complexes with palladium chloride. It is a precursor to O-acyl thiohydroxamates. Further, it serves as an antifungal agent. In addition to this, it is used in the preparation of 1-oxa-2-oxo-3-thia-indolizinium chloride by reaction with carbonyl dichloride.

Uses

Precursor to O-acyl thiohydroxamates. Ligates to metals to form biologically active complexes.

Definition

ChEBI: Pyrithione is a pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent. It has a role as an ionophore. It is a pyridinethione and a monohydroxypyridine. It is a tautomer of a pyridine-2-thiol N-oxide.

General Description

2-Mercaptopyridine N-oxide forms complexes on reaction with palladium chloride. It inhibits NADH-fumarate reductase purified from Trypanosoma cruzi. It is precursor to O-acyl thiohydroxamates. It ligates to metals to form biologically active complexes.

2-Pyridinethiol 1-oxide Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Pyridinethiol 1-oxide Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
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Alfa Aesar
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400-6106006
Fax
021-67582001/03/05
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saleschina@alfa-asia.com
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China
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TAIYUAN RHF CO.,LTD.
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+86 351 7031519
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+86 351 7031519
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sales@RHFChem.com
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China
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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021-67121385
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Sales-CN@TCIchemicals.com
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China
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Energy Chemical
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sales8178@energy-chemical.com
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China
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Beijing Ouhe Technology Co., Ltd
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13552068683 13522913783
Fax
+86-10-82967029
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2355560935@qq.com
Country
China
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
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China
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9254
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Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
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Adamas Reagent, Ltd.
Tel
400-6009262 15618770481
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021-64823266
Email
yhx@titansci.com
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China
ProdList
14100
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View Lastest Price from 2-Pyridinethiol 1-oxide manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Pyridinethiol 1-oxide 1121-31-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Mercaptopyridine N-Oxide 1121-31-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Hebei shuoxi biotechnology co. LTD
Product
Pyrithione 1121-31-9
Price
US $90.00/g
Min. Order
10g
Purity
99.8%
Supply Ability
10tons
Release date
2020-04-26

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