ChemicalBook > CAS DataBase List > Methylglyoxal 1,1-dimethyl acetal

Methylglyoxal 1,1-dimethyl acetal

Product Name
Methylglyoxal 1,1-dimethyl acetal
CAS No.
6342-56-9
Chemical Name
Methylglyoxal 1,1-dimethyl acetal
Synonyms
1,1-Dimethoxypropan-2-one;1,1-DIMETHOXYACETONE;PYRUVIC ALDEHYDE DIMETHYL ACETAL;2,2-DiMethoxypropanal;2-Propanone, 1,1-dimethoxy-;Pyruvic aL;Pyruvaldehyde 1;1,1-Dimethoxyaceton;Methylglyoxal 1,1-di;1,1-Dimethoxypropanone
CBNumber
CB0166610
Molecular Formula
C5H10O3
Formula Weight
118.13
MOL File
6342-56-9.mol
More
Less

Methylglyoxal 1,1-dimethyl acetal Property

Melting point:
-57 °C
Boiling point:
143-147 °C(lit.)
Density 
0.976 g/mL at 25 °C(lit.)
vapor pressure 
11hPa at 20℃
refractive index 
n20/D 1.398(lit.)
Flash point:
100 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
Liquid
color 
Clear colorless to yellow
Water Solubility 
MISCIBLE
BRN 
1560557
InChIKey
ULVSHNOGEVXRDR-UHFFFAOYSA-N
LogP
-0.199 (est)
CAS DataBase Reference
6342-56-9
NIST Chemistry Reference
2-Propanone, 1,1-dimethoxy-(6342-56-9)
EPA Substance Registry System
2-Propanone, 1,1-dimethoxy- (6342-56-9)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
10-36/38
Safety Statements 
26-36-16
RIDADR 
UN 1224 3/PG 3
WGK Germany 
1
TSCA 
Yes
HazardClass 
3
PackingGroup 
III
HS Code 
29145000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
170216
Product name
Methylglyoxal 1,1-dimethyl acetal
Purity
≥97%
Packaging
100ml
Price
$91.6
Updated
2024/03/01
Sigma-Aldrich
Product number
170216
Product name
Methylglyoxal 1,1-dimethyl acetal
Purity
≥97%
Packaging
500ml
Price
$104.4
Updated
2024/03/01
TCI Chemical
Product number
P1264
Product name
Pyruvic Aldehyde Dimethyl Acetal
Purity
>97.0%(GC)
Packaging
25mL
Price
$75
Updated
2024/03/01
TCI Chemical
Product number
P1264
Product name
Pyruvic Aldehyde Dimethyl Acetal
Purity
>97.0%(GC)
Packaging
100mL
Price
$154
Updated
2024/03/01
Alfa Aesar
Product number
B24988
Product name
Pyruvic aldehyde dimethyl acetal, 97+%
Packaging
100g
Price
$46.65
Updated
2024/03/01
More
Less

Methylglyoxal 1,1-dimethyl acetal Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellow liquid

Uses

Pyruvic Aldehyde Dimethyl Acetal is used in the preparation of MCL1 inhibitors S63845 which is tolerable and effective in diverse cancer models. Also, acts as a synthetic reagent for the preparation of 8novel 2,4-disubstituted pyrimidines as potent, selective, and cell-permeable inhibitors of neuronal nitric oxide synthase. Selective inhibition of neuronal nitric oxide synthase is an important therapeutic approach to target neurodegenerative disorders.

Uses

Methylglyoxal 1,1-dimethyl acetal was used in the synthesis of methylglyoxal via hydrolysis in the presence of H2SO4. It was used to investigate the effects of methylglyoxal-mediated glycation on the structure, thermal stability and enzyme activity of yeast enolase in vivo.

Synthesis Reference(s)

The Journal of Organic Chemistry, 41, p. 2642, 1976 DOI: 10.1021/jo00877a030

Methylglyoxal 1,1-dimethyl acetal Preparation Products And Raw materials

Raw materials

Methylglyoxal

Preparation Products

4-DIMETHOXYMETHYL-6-HYDROXYPYRIMIDINE-2-THIOL
More
Less

Methylglyoxal 1,1-dimethyl acetal Suppliers

Americas 1 Belgium 3 Canada 1 China 271 Europe 2 France 1 Germany 9 India 10 Italy 1 Japan 2 South Korea 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 9 United States 52 USA 1 Global 368
Acros Organics (Part of Thermo Fisher Scientific )
Tel
--
Fax
--
Email
fo@acros.com
Country
Belgium
ProdList
3824
Advantage
58
Alkemi BVBA
Tel
--
Fax
--
Email
nfo@alkemi.be
Country
Belgium
ProdList
2201
Advantage
58
Acros Organics
Tel
--
Fax
--
Email
info@acros.com
Country
Belgium
ProdList
6772
Advantage
81
More
Less

View Lastest Price from Methylglyoxal 1,1-dimethyl acetal manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
1,1-Dimethoxyacetone 6342-56-9
Price
US $100.00-10.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20000kg per day
Release date
2023-09-05
Hebei Weibang Biotechnology Co., Ltd
Product
1,1-Dimethoxyacetone 6342-56-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-24
Hebei Chuanghai Biotechnology Co,.LTD
Product
Methylglyoxal 1,1-dimethyl acetal 6342-56-9
Price
US $100.00-50.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-19

6342-56-9, Methylglyoxal 1,1-dimethyl acetalRelated Search:

Chloroacetaldehyde dimethyl acetal Paraldehyde Acetal 1,1-Dimethoxyethane Benzaldehyde dimethyl acetal 1-Nonanal Diphenyldimethoxysilane Dimethyldimethoxysilane Methylglyoxal Acetylacetaldehyde dimethyl acetal Bromoacetaldehyde dimethyl acetal Methoxyacetone 4-Methoxyphenylacetone Benzhydrol 2,2-Dimethoxypropane 1,1,2-Trimethoxyethane N,N-Dimethylformamide Dimethyl fumarate Methylglyoxal Dimethyl Acetal

  • PYRUVIC ALDEHYDE DIMETHYL ACETAL
  • PYRUVALDEHYDE DIMETHYLACETAL
  • PYRUVALDEHYDE 1,1-DIMETHYL ACETAL
  • PYRUVALDEHYDE-1-DIMETHYL ACETAL
  • Methylglyoxal dimethyl acetal~Pyruvaldehyde dimethyl acetal
  • PYRUVIC ALDEHYDE DIMETHYL ACETAL, 97+%
  • PYRUVIC ALDEHYDE DIMETHYL ACETAL 98%
  • PYRUVIC ALDEHYDE DIMETHYL ACETAL(INTERMEDIATE OF B-CAROTENE)
  • 2-Propanone, 1,1-dimethoxy- (9CI)
  • 1,1-Dimethoxypropan-2-one
  • 2-Propanone, 1,1-dimethoxy-
  • PYRUVICALDEHYDEDIETHYLACETAL
  • 1,1-Dimethoxyaceton
  • Pyruvic aldehyde dimethyl aecetal
  • 1,1-Dimethoxypropane-2-one
  • 2-Oxopropanal dimethyl acetal
  • Pyruvic aldehyde dimethyl acetal,98%
  • 1,1-Dimethoxypropanone
  • 1,1-Dimethoxyacetone, Pyruvaldehyde-1-dimethyl acetal, Pyruvic aldehyde dimethyl acetal
  • Pyruvic aL
  • Methylglyoxal 1,1-di
  • Acetone, Methanol aldolase two
  • 1,1-Dimethoxypropan-2-one, Methylglyoxal dimethyl acetal, Pyruvaldehyde dimethyl acetal
  • 1,1-Dimethoxyaceton (Methylglyoxaldimethylacetal)
  • 1,1-Dimethoxyacetone 1,1-Dimethoxy-2-propanone Methylglyoxal Dimethyl Acetal
  • 2,2-DiMethoxypropanal
  • Methylglyoxal 1,1-diMethyl acetal >=97%
  • 1,1-DIMETHOXY-2-PROPANONE
  • 1,1-DIMETHOXYACETONE
  • Methylglyoxal 1,1-dimethyl aceta
  • ACETYLFORMALDEHYDE DIMETHYL ACETAL
  • ALPHA,ALPHA-DIMETHOXYACETONE
  • METHYLGLYOXAL 1, 1-DIMETHYL ACETAL
  • METHYLGLYOXAL DIMETHYL ACETAL
  • 1,1-dimethoxy-2-propanon
  • Dimethoxymethyl methyl ketone
  • Acetone aldehyde condensation of Methanol
  • Pyruvaldehyde dimethyl acetal estimate
  • PyruvicAldehydeDimethylAcetal&gt
  • Methylglyoxaldimethyl acetal (Pyruvicaldehyde dimethylacetal)
  • Pyruvaldehyde 1
  • Pyruvaldehyde dimethyl acetal English name: Pyruvic aldehyde dimethyl acetal
  • Methylglyoxal Dimethyl Acetal [MGDA]
  • 6342-56-9
  • 6342-59-9
  • CH3COCHOCH32
  • Organic Building Blocks
  • Oxygen Compounds
  • Acetals/Ketals/Ortho Esters
  • Building Blocks
  • ACETYLGROUP
  • Aldehydes
  • blocks
  • BuildingBlocks
  • ketone
  • (intermediate of -carotene)