Methylglyoxal 1,1-dimethyl acetal

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Methylglyoxal 1,1-dimethyl acetal

Product Name: Methylglyoxal 1,1-dimethyl acetal
CAS No.: 6342-56-9
Chemical Name: Methylglyoxal 1,1-dimethyl acetal
Synonyms: 1,1-Dimethoxypropan-2-one;1,1-DIMETHOXYACETONE;PYRUVIC ALDEHYDE DIMETHYL ACETAL;2,2-DiMethoxypropanal;2-Propanone, 1,1-dimethoxy-;Pyruvic aL;Pyruvaldehyde 1;1,1-Dimethoxyaceton;Methylglyoxal 1,1-di;1,1-Dimethoxypropanone
CBNumber: CB0166610
Molecular Formula: C5H10O3
Formula Weight: 118.13
MOL File: 6342-56-9.mol

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Methylglyoxal 1,1-dimethyl acetal Property

Melting point:: -57 °C
Boiling point:: 143-147 °C(lit.)
Density: 0.976 g/mL at 25 °C(lit.)
vapor pressure: 11hPa at 20℃
refractive index: n20/D 1.398(lit.)
Flash point:: 100 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: Liquid
color: Clear colorless to yellow
Water Solubility: MISCIBLE
BRN: 1560557
InChIKey: ULVSHNOGEVXRDR-UHFFFAOYSA-N
LogP: -0.199 (est)
CAS DataBase Reference: 6342-56-9
NIST Chemistry Reference: 2-Propanone, 1,1-dimethoxy-(6342-56-9)
EPA Substance Registry System: 2-Propanone, 1,1-dimethoxy- (6342-56-9)

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Safety

Hazard Codes: Xi
Risk Statements: 10-36/38
Safety Statements: 26-36-16
RIDADR: UN 1224 3/PG 3
WGK Germany: 1
TSCA: Yes
HazardClass: 3
PackingGroup: III
HS Code: 29145000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 170216
Product name: Methylglyoxal 1,1-dimethyl acetal
Purity: ≥97%
Packaging: 100ml
Price: $91.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 170216
Product name: Methylglyoxal 1,1-dimethyl acetal
Purity: ≥97%
Packaging: 500ml
Price: $104.4
Updated: 2024/03/01

TCI Chemical

Product number: P1264
Product name: Pyruvic Aldehyde Dimethyl Acetal
Purity: >97.0%(GC)
Packaging: 25mL
Price: $75
Updated: 2024/03/01

TCI Chemical

Product number: P1264
Product name: Pyruvic Aldehyde Dimethyl Acetal
Purity: >97.0%(GC)
Packaging: 100mL
Price: $154
Updated: 2024/03/01

Alfa Aesar

Product number: B24988
Product name: Pyruvic aldehyde dimethyl acetal, 97+%
Packaging: 100g
Price: $46.65
Updated: 2024/03/01

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Methylglyoxal 1,1-dimethyl acetal Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellow liquid

Uses

Pyruvic Aldehyde Dimethyl Acetal is used in the preparation of MCL1 inhibitors S63845 which is tolerable and effective in diverse cancer models. Also, acts as a synthetic reagent for the preparation of 8novel 2,4-disubstituted pyrimidines as potent, selective, and cell-permeable inhibitors of neuronal nitric oxide synthase. Selective inhibition of neuronal nitric oxide synthase is an important therapeutic approach to target neurodegenerative disorders.

Uses

Methylglyoxal 1,1-dimethyl acetal was used in the synthesis of methylglyoxal via hydrolysis in the presence of H₂SO₄. It was used to investigate the effects of methylglyoxal-mediated glycation on the structure, thermal stability and enzyme activity of yeast enolase in vivo.

Synthesis Reference(s)

The Journal of Organic Chemistry, 41, p. 2642, 1976 DOI: 10.1021/jo00877a030

Methylglyoxal 1,1-dimethyl acetal Preparation Products And Raw materials

Raw materials

Methylglyoxal

Preparation Products

4-DIMETHOXYMETHYL-6-HYDROXYPYRIMIDINE-2-THIOL

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View Lastest Price from Methylglyoxal 1,1-dimethyl acetal manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Methylglyoxal 1,1-dimethyl acetal 6342-56-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-12-02

Hebei Yanxi Chemical Co., Ltd.

Product: 1,1-Dimethoxyacetone 6342-56-9
Price: US $100.00-10.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20000kg per day
Release date: 2023-09-05

Hebei Weibang Biotechnology Co., Ltd

Product: 1,1-Dimethoxyacetone 6342-56-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-24

6342-56-9, Methylglyoxal 1,1-dimethyl acetalRelated Search:

Chloroacetaldehyde dimethyl acetal Paraldehyde Acetal 1,1-Dimethoxyethane Benzaldehyde dimethyl acetal 1-Nonanal Diphenyldimethoxysilane Dimethyldimethoxysilane Methylglyoxal Acetylacetaldehyde dimethyl acetal Bromoacetaldehyde dimethyl acetal Methoxyacetone 4-Methoxyphenylacetone Benzhydrol 2,2-Dimethoxypropane 1,1,2-Trimethoxyethane N,N-Dimethylformamide Dimethyl fumarate Methylglyoxal Dimethyl Acetal

PYRUVIC ALDEHYDE DIMETHYL ACETAL

PYRUVALDEHYDE DIMETHYLACETAL

PYRUVALDEHYDE 1,1-DIMETHYL ACETAL

PYRUVALDEHYDE-1-DIMETHYL ACETAL

Methylglyoxal dimethyl acetal~Pyruvaldehyde dimethyl acetal

PYRUVIC ALDEHYDE DIMETHYL ACETAL, 97+%

PYRUVIC ALDEHYDE DIMETHYL ACETAL 98%

PYRUVIC ALDEHYDE DIMETHYL ACETAL(INTERMEDIATE OF B-CAROTENE)

2-Propanone, 1,1-dimethoxy- (9CI)

1,1-Dimethoxypropan-2-one

2-Propanone, 1,1-dimethoxy-

PYRUVICALDEHYDEDIETHYLACETAL

1,1-Dimethoxyaceton

Pyruvic aldehyde dimethyl aecetal

1,1-Dimethoxypropane-2-one

2-Oxopropanal dimethyl acetal

Pyruvic aldehyde dimethyl acetal,98%

1,1-Dimethoxypropanone

1,1-Dimethoxyacetone, Pyruvaldehyde-1-dimethyl acetal, Pyruvic aldehyde dimethyl acetal

Pyruvic aL

Methylglyoxal 1,1-di

Acetone, Methanol aldolase two

1,1-Dimethoxypropan-2-one, Methylglyoxal dimethyl acetal, Pyruvaldehyde dimethyl acetal

1,1-Dimethoxyaceton (Methylglyoxaldimethylacetal)

1,1-Dimethoxyacetone 1,1-Dimethoxy-2-propanone Methylglyoxal Dimethyl Acetal

2,2-DiMethoxypropanal

Methylglyoxal 1,1-diMethyl acetal >=97%

1,1-DIMETHOXY-2-PROPANONE

1,1-DIMETHOXYACETONE

Methylglyoxal 1,1-dimethyl aceta

ACETYLFORMALDEHYDE DIMETHYL ACETAL

ALPHA,ALPHA-DIMETHOXYACETONE

METHYLGLYOXAL 1, 1-DIMETHYL ACETAL

METHYLGLYOXAL DIMETHYL ACETAL

1,1-dimethoxy-2-propanon

Dimethoxymethyl methyl ketone

Acetone aldehyde condensation of Methanol

Pyruvaldehyde dimethyl acetal estimate

PyruvicAldehydeDimethylAcetal&gt

Methylglyoxaldimethyl acetal (Pyruvicaldehyde dimethylacetal)

Pyruvaldehyde 1

Pyruvaldehyde dimethyl acetal English name: Pyruvic aldehyde dimethyl acetal

Methylglyoxal Dimethyl Acetal [MGDA]

6342-56-9

6342-59-9

CH3COCHOCH32

Organic Building Blocks

Oxygen Compounds

Acetals/Ketals/Ortho Esters

Building Blocks

ACETYLGROUP

Aldehydes

blocks

BuildingBlocks

ketone

(intermediate of -carotene)