Anethole trithione

Description

Product Name: Anethole trithione
CAS No.: 532-11-6
Chemical Name: Anethole trithione
Synonyms: Sulfarlem;AnetholTrithione;Trithio;Heporal;Mucinol;skf1717;Sulfogal;Felviten;SKF 1717;Sufralem
CBNumber: CB0168937
Molecular Formula: C10H8OS3
Formula Weight: 240.36
MOL File: 532-11-6.mol

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Anethole trithione Property

Melting point:: 111°
Boiling point:: 353.09°C (rough estimate)
Density: 1.4406 (rough estimate)
refractive index: 1.5080 (estimate)
storage temp.: 2-8°C
solubility: soluble in Chloroform
form: powder to crystal
color: Orange-colored prisms from butyl acetate
Odor: very bitter taste
InChI: InChI=1S/C10H8OS3/c1-11-8-4-2-7(3-5-8)9-6-10(12)14-13-9/h2-6H,1H3
InChIKey: KYLIZBIRMBGUOP-UHFFFAOYSA-N
SMILES: S1C(C2=CC=C(OC)C=C2)=CC(=S)S1
CAS DataBase Reference: 532-11-6(CAS DataBase Reference)
NIST Chemistry Reference: 3H-1,2-Dithiole-3-thione, 5-(4-methoxyphenyl)-(532-11-6)

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Safety

HS Code: 2934.99.3000
Toxicity: LD50 orl-mus: 3850 mg/kg NIIRDN 6,25,82

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A3364
Product name: Anethole Trithione
Packaging: 5G
Price: $70
Updated: 2024/03/01

TCI Chemical

Product number: A3364
Product name: Anethole Trithione
Packaging: 25G
Price: $278
Updated: 2024/03/01

Biosynth Carbosynth

Product number: FA41106
Product name: Anethole trithione
Packaging: 500mg
Price: $90
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA41106
Product name: Anethole trithione
Packaging: 5G
Price: $375
Updated: 2021/12/16

Matrix Scientific

Product number: 074707
Product name: Anethole trithione
Purity: 95+%
Packaging: 5g
Price: $599
Updated: 2021/12/16

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Anethole trithione Chemical Properties,Usage,Production

Description

Anise trisulfide, also known as bile vita, is a secretory choleretic drug, which can significantly enhance liver glutathione levels, significantly enhance glutamyl cysteine synthase, glutathione reductase and glutathione sulfur Transferase activity, reduce glutathione peroxidase activity, enhance liver cell viability, and increase bile secretion. Without increasing the burden on the liver, it can reduce liver portal pressure, eliminate liver congestion and other symptoms of hepatitis lesions, promote liver cell activation, and contribute to the improvement and recovery of liver function.

Originator

Sialor,Paladin Labs

Uses

Anethole trithione is a choleretic drug that can be effective in the treatment of dry mouth, including drug-induced xerostomia. Research suggests that Anethole trithione may exert its therapeutic effects by acting on the alpha-CGRP nerves in the salivary glands, which in turn promotes salivary secretion^[1-2].

Definition

ChEBI: Anetholtrithion is a member of methoxybenzenes.

Manufacturing Process

1 mol anethol (1-methoxy-4-propenyl-benzene) and 3 mol sulfur were heated in an open vessel to temperature 190°-200°C. H2S was removed at this temperature. On cooling the reaction mixture was getting solid. The solid product was recrystallizated from acetone or ethanol to give the orange-red needles of 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione; MP 108.5°C.

Therapeutic Function

Salivation stimulant, Choleretic, Neuroprotective

Safety Profile

Poison by intramuscular route.Moderately toxic by ingestion and intraperitoneal routes.Experimental reproductive effects. When heated todecomposition it emits toxic fumes of SOx.

References

[1] TOSHIAKI NAGANO; Masaharu T. Enhancement of salivary secretion and neuropeptide (substance P, α-calcitonin gene-related peptide) levels in saliva by chronic anethole trithione treatment[J]. Journal of Pharmacy and Pharmacology, 2010. DOI:10.1211/0022357011778098.
[2] GLENERT U. Effects of chronic anethole trithione and amitriptyline treatment on rat parotid gland signalling[J]. European Journal of Pharmacology: Molecular Pharmacology, 1992. DOI:10.1016/0922-4106(92)90081-6.

Anethole trithione Preparation Products And Raw materials

Raw materials

cis-Anethol Sulfur Butyl acetate

Preparation Products

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Anethole trithione Suppliers

Americas 1 China 244 Europe 1 Germany 1 India 5 Japan 2 United Kingdom 6 United States 26 USA 1 Global 287

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View Lastest Price from Anethole trithione manufacturers

Sinoway Industrial co., ltd.

Product: Anethol Trithione 532-11-6
Price: US $0.00/Kg/Bag
Min. Order: 2Kg/Bag
Purity: 0.99
Supply Ability: 20 tons
Release date: 2022-12-02

Hebei Weibang Biotechnology Co., Ltd

Product: Anethole trithione 532-11-6
Price: US $10.00/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-11-29

HUBEI VITORCOME PHARMACEUTICAL CO.,LTD

Product: Anethol Trithione 532-11-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 20 ton
Release date: 2024-09-04

532-11-6, Anethole trithioneRelated Search:

1,3-Cyclopentadiene 1,2-PENTADIENE 4-Methoxyphenylacetone TRANS-1,3-PENTADIENE DL-Limonene Cyclopentene Dicyclopentadiene trans-Anethole METHYLCYCLOPENTADIENE DIMER N,N-DIETHYLNICOTINAMIDE GALL Chicken gold BENZYL METHYL DISULFIDE cis-Anethol 5-PHENYL-3H-1,2-DITHIOLE-3-THIONE 3H-1,2-DITHIOLE-3-THIONE Anethole trithione

Anetholi Trithionum

5-(4-methoxyphenyl)dithiole-3-thione

(E)-O-4-(prop-1-enyl)-5,6-dithioxocyclohexa-1,3-dienyl methanethioate

4-(prop-1-en-1-yl)-5,6-disulfanylidenecyclohexa-1,3-dien-1-yl carbothioate

Anethol trithione ,5-(4-Methoxyphenyl)-1,2-dithiole-3-thione

Anethali Trithinum

ANETHOLE TRITHIONE

5-(4-methoxyphenyl)-3h-1,2-dithiole-3-thione

5-(4-methoxyphenyl)-1,2-dithiole-3-thione

3-(p-anisy)trithione

3-(p-Methoxyphenyl)trithione

3-(p-Methoxyphenyl)-trithione

Sulfarlem

Sulfogal

Sulfralem

Tiopropen

Tiotrifar

Trithio

Trithio-(p-methoxyphenyl)propene

Trithioanethole

methanethioic acid O-[4-prop-1-enyl-2,3-bis(sulfanylidene)cyclohexyl] ester

3H-1,2-Dithiole-3-thione, 5-(p-methoxyphenyl)-

AnetholTrithione

Felviten

Heporal

Mucinol

SKF 1717

skf1717

Sufralem

5-(4-methoxyphenyl)-3h-2-dithiole-3-thione

5-(p-Methoxyphenyl)-1,2-dithiocyclopenten-3-thione

5-(p-Methoxyphenyl)-3H-1,2-dithiole-3-thione

5-(p-methoxyphenyl)-3h-2-dithiole-3-thione

Anethol Trithione,Felviten

3H-1,2-Dithiole-3-thione, 5-(4-methoxyphenyl)-

Anethole trithione USP/EP/BP

Anethole trithione CAS 532-11-6

TIANFU-CHEM - Anethole trithione

34S3]-Anethole trithione

532-11-6

532-11-2

523-11-6

C10H8OS3