ChemicalBook > CAS DataBase List > Alpha-D-Lactose monohydrate

Alpha-D-Lactose monohydrate

Product Name
Alpha-D-Lactose monohydrate
CAS No.
5989-81-1
Chemical Name
Alpha-D-Lactose monohydrate
Synonyms
LACTOSE MONOHYDRATE;α-Lactose;MILK SUGAR;ALPHA-LACTOSE MONOHYDRATE;ALPHA-D-LACTOSE;α-D-Lactose monohydrate;A-LACTOSE;Pharmatose 150M;ALPHA-LACTOSE MONOHY;A-LACTOSE MONOHYDRATE
CBNumber
CB0177832
Molecular Formula
C12H24O12
Formula Weight
360.31
MOL File
5989-81-1.mol
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Alpha-D-Lactose monohydrate Property

Melting point:
219 °C
Boiling point:
412.35°C (rough estimate)
alpha 
[α]D20+52.2～+52.8°
Density 
1,53 g/cm3
refractive index 
1.6480 (estimate)
RTECS 
OD9625000
storage temp. 
Inert atmosphere,Room Temperature
solubility 
H2O: soluble1M, clear, colorless
form 
Solid
color 
White to Off-White
PH
pH (50g/l, 25℃) : 4.0～6.0
Water Solubility 
Soluble in water.
Stability:
Hygroscopic
InChIKey
WSVLPVUVIUVCRA-KPKNDVKVSA-N
CAS DataBase Reference
5989-81-1(CAS DataBase Reference)
EPA Substance Registry System
.alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, hydrate (1:1) (5989-81-1)
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Safety

Hazard Codes 
Xi
Risk Statements 
40-36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3
TSCA 
Yes
HS Code 
17021100
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L2643
Product name
α-Lactose monohydrate
Purity
suitable for cell culture, BioReagent
Packaging
5kg
Price
$163
Updated
2024/03/01
Sigma-Aldrich
Product number
47287-U
Product name
Lactose Monohydrate
Purity
analyticalstandard
Packaging
1kit
Price
$24.8
Updated
2024/03/01
Alfa Aesar
Product number
A11074
Product name
alpha-D-Lactose monohydrate
Packaging
250g
Price
$23.65
Updated
2024/03/01
Alfa Aesar
Product number
A11074
Product name
alpha-D-Lactose monohydrate
Packaging
1000g
Price
$56.65
Updated
2024/03/01
Alfa Aesar
Product number
036218
Product name
alpha-D-Lactose monohydrate
Purity
ACS
Packaging
500g
Price
$46.3
Updated
2023/06/20
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Alpha-D-Lactose monohydrate Chemical Properties,Usage,Production

Chemical Properties

White powder

Chemical Properties

Lactose occurs as white to off-white crystalline particles or powder. It is odorless and slightly sweet-tasting. Spray-dried directcompression grades of lactose are generally composed of 80–90% specially prepared pure a-lactose monohydrate along with 10–20% of amorphous lactose.

Uses

alpha-D-Lactose monohydrate is used as a carrier and stabiliser of aromas, pharmaceutical products, Food industry.

Production Methods

A suspension of a-lactose monohydrate crystals in a lactose solution is atomized and dried in a spray drier. Approximately 10–20% of the total amount of lactose is in solution and the remaining 80–90% is present in the crystalline form. The spray-drying process predominantly produces spherical particles. The compactibility of the material and its flow characteristics are a function of the primary particle size of the lactose monohydrate and the amount of amorphous lactose.

Definition

A sugar that occurs in many plants. It is extracted commercially from sugar cane and sugar beet. Sucrose is a disaccharide formed from a glucose unit and a fructose unit. It is hydrolyzed to a mixture of fructose and glucose by the enzyme invertase. Since this mixture has a different optical rotation (levorotatory) than the original sucrose, the mixture is called invert sugar.

Pharmaceutical Applications

Spray-dried lactose is widely used as a binder, filler-binder, and flow aid in direct compression tableting.

Biochem/physiol Actions

alpha-Lactose is the primary sugar present in milk and the main energy source to a newborn mammalian through its mother′s milk. It is digested by the intestinal lactase (EC 3.2.1.108), an enzyme expressed in newborns. The enzyme′s activity declines following weaning which can lead to lactose intolerance in adult mammals.

Safety

Lactose is widely used in pharmaceutical formulations as a diluent in oral capsule and tablet formulations. It may also be used in intravenous injections.
Adverse reactions to lactose are largely due to lactose intolerance, which occurs in individuals with a deficiency of the enzyme lactase.

storage

Spray-dried lactose should be stored in a well-closed container in a cool, dry place.

Incompatibilities

Lactose is a reducing sugar. The amorphous lactose, which is the most reactive form of lactose present in spray-dried lactose, will interact more readily than conventional crystalline grades. Typical reactions include the Maillard reaction with either primary or secondary amines.

Alpha-D-Lactose monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Alpha-D-Lactose monohydrate Suppliers

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View Lastest Price from Alpha-D-Lactose monohydrate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Alpha-D-Lactose monohydrate 5989-81-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-12-02
Hebei Fengjia New Material Co., Ltd
Product
Alpha-D-Lactose monohydrate 5989-81-1
Price
US $3.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
1000
Release date
2024-08-16
Henan Fengda Chemical Co., Ltd
Product
Alpha-D-Lactose monohydrate 5989-81-1
Price
US $8.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09

5989-81-1, Alpha-D-Lactose monohydrateRelated Search:

Saccharin D-Xylose Isomalt Alitame Glycyrrhizic acid L-xylose N-Acetyl-D-Glucosamine EMULSIFIER Lactose Thickening agent Sulfamic acid LACTOSE, MONOHYDRATE MONELLIN EDIBLE LACTOSE D(+)-Glucose D-Lactose monohy ALPHA-LACTOSE, MONOHYDRATE D-Glucose monohydrate Lactose Monohydrate

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