2',4',5'-TRIMETHOXYACETOPHENONE

Product Name: 2',4',5'-TRIMETHOXYACETOPHENONE
CAS No.: 1818-28-6
Chemical Name: 2',4',5'-TRIMETHOXYACETOPHENONE
Synonyms: 2,4,5-TRIMETHOXYACETOPHENONE;trimethyl(1-pyrazolyl)silane;2'，4'，5'-Trimethoxyacetophenone;2',4',5'-TRIMETHOXYACETOPHENONE;Acetophenone, 2',4',5'-trimethoxy-;1-(2,4,5-Trimethoxyphenyl)ethanone;1-(2,4,5-trimethoxyphenyl)ethan-1-one;Ethanone, 1-(2,4,5-trimethoxyphenyl)-
CBNumber: CB0184667
Molecular Formula: C11H14O4
Formula Weight: 210.23
MOL File: 1818-28-6.mol

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2',4',5'-TRIMETHOXYACETOPHENONE Property

Melting point:: 98-102°C
Boiling point:: 285-290 °C(Press: 33 Torr)
Density: 1.089±0.06 g/cm3(Predicted)
EPA Substance Registry System: Ethanone, 1-(2,4,5-trimethoxyphenyl)- (1818-28-6)

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Safety

Hazard Codes: Xi
Risk Statements: 36
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 711233
Product name: 2′,4′,5′-Trimethoxyacetophenone
Purity: 97%
Packaging: 25g
Price: $40.4
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: CHM0129205
Product name: 2',4',5'-TRIMETHOXYACETOPHENONE
Purity: 97.00%
Packaging: 25G
Price: $1178.79
Updated: 2021/12/16

AHH

Product number: MT-31478
Product name: 2,4,5-Trimethoxyacetophenone
Purity: 98%
Packaging: 10g
Price: $455
Updated: 2021/12/16

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2',4',5'-TRIMETHOXYACETOPHENONE Chemical Properties,Usage,Production

Preparation

Preparation by reaction of acetyl chloride with hydroxyhydroquinone trimethyl ether in the presence of aluminium chloride.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 33, p. 1155, 1990 DOI: 10.1021/jm00166a012

Synthesis

2,4,5-Trimethoxy acetophenone is synthesised using 2-Hydroxy-4,5-dimethoxy acetophenone as raw material by chemical reaction. The specific synthesis steps are as follows:
2-Hydroxy-4,5-dimethoxyacetophenone(5 g,0.0255 mole) in dry acetone (100 ml)is refluxed for 30 hr under anhydrous conditions with dimethyl sulphate (2.8 ml,3.78 g,0.03 mole)and ignited potassium carbonate (20 g).The mixture is filtered and the inorganic residue washed with hot acetone (2 x 20 ml).The combined acetone solution is distilled and the oily residue macerated with crushed ice.The solid product is filtered,washed with water and dried.It is crystallised from benzene as colourless needles.Yield 4.5g (84.1%).M.p.97(lit.m.p.102).

2',4',5'-TRIMETHOXYACETOPHENONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2',4',5'-TRIMETHOXYACETOPHENONE Suppliers

China 14 Germany 1 United Kingdom 5 United States 7 Global 27

Energy Chemical

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Sigma-Aldrich

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1818-28-6, 2',4',5'-TRIMETHOXYACETOPHENONERelated Search:

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2',4',5'-TRIMETHOXYACETOPHENONE

2,4,5-TRIMETHOXYACETOPHENONE

1-(2,4,5-Trimethoxyphenyl)ethanone

Acetophenone, 2',4',5'-trimethoxy-

Ethanone, 1-(2,4,5-trimethoxyphenyl)-

1-(2,4,5-trimethoxyphenyl)ethan-1-one

trimethyl(1-pyrazolyl)silane

2'，4'，5'-Trimethoxyacetophenone

1818-28-6

KETONE

Aromatic Acetophenones & Derivatives (substituted)