4-Biphenylacetic acid
- Product Name
- 4-Biphenylacetic acid
- CAS No.
- 5728-52-9
- Chemical Name
- 4-Biphenylacetic acid
- Synonyms
- FELBINAC;Napageln;BIPHENYL-4-ACETIC ACID;[1,1'-BIPHENYL]-4-ACETIC ACID;2-([1,1'-biphenyl]-4-yl)acetic acid;L-141;TraxaM;LY-61017;Seltouch;CI 83544
- CBNumber
- CB0186272
- Molecular Formula
- C14H12O2
- Formula Weight
- 212.24
- MOL File
- 5728-52-9.mol
4-Biphenylacetic acid Property
- Melting point:
- 159-160 °C (lit.)
- Boiling point:
- 312.08°C (rough estimate)
- Density
- 1.1035 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble50mg/mL, clear, colorless to yellow
- form
- Powder
- pka
- 4.29±0.10(Predicted)
- color
- Beige
- Water Solubility
- 39.27mg/L(25 ºC)
- Merck
- 14,3316
- BRN
- 1211592
- InChIKey
- QRZAKQDHEVVFRX-UHFFFAOYSA-N
- CAS DataBase Reference
- 5728-52-9(CAS DataBase Reference)
Safety
- Hazard Codes
- T,Xn
- Risk Statements
- 23/25-36/37/38-25-36/37/38/63-20/21/22
- Safety Statements
- 26-36/37/39-45-37/39-28A-26/36/3745/60-20-36
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- DU8229050
- Hazard Note
- Irritant
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29163900
- Toxicity
- LD50 orally in rats: 164 mg/kg (Sloboda, Osterberg)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 196487
- Product name
- 4-Biphenylacetic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $60.2
- Updated
- 2024/03/01
- Product number
- 196487
- Product name
- 4-Biphenylacetic acid
- Purity
- 98%
- Packaging
- 25g
- Price
- $120
- Updated
- 2023/01/07
- Product number
- B1278
- Product name
- 4-Biphenylacetic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $41
- Updated
- 2024/03/01
- Product number
- B1278
- Product name
- 4-Biphenylacetic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 250g
- Price
- $232
- Updated
- 2024/03/01
- Product number
- A11749
- Product name
- 4-Biphenylacetic acid, 98%
- Packaging
- 50g
- Price
- $151
- Updated
- 2023/06/20
4-Biphenylacetic acid Chemical Properties,Usage,Production
Description
Felbinac Is the active metabolite of the non-steroidal antiinflammatory agent, fenbufen. Applied topically as a gel to joints, it is useful in the symptomatic relief of articular inflammation and pain.
Chemical Properties
Off-white powder
Originator
Lederle (USA)
Uses
Anti-inflammatory, analgesic drug.
Uses
4-Biphenylacetic acid was used in the synthesis of gastrosparing non-steroidal antiinflammatory drug.
Definition
ChEBI: Biphenyl-4-ylacetic acid is a monocarboxylic acid in which one of the alpha-hydrogens is substituted by a biphenyl-4-yl group. An active metabolite of fenbufen, it is used as a topical medicine to treat muscle inflammation and arthritis. It has a role as a non-steroidal anti-inflammatory drug. It is a member of biphenyls and a monocarboxylic acid. It contains a biphenyl-4-yl group. It is functionally related to an acetic acid.
brand name
Dolinac (Wyeth-Ayerst); Flexfree(Wyeth-Ayerst); Napageln (Wyeth-Ayerst); Target (Wyeth-Ayerst); Traxam (Wyeth-Ayerst).
General Description
4-Biphenylacetic acid is a potential non-steroidal antiinflammatory agent and forms solid inclusion complex with β-cyclodextrin. 4-Biphenylacetic acid on interaction with quinolone antibacterial agents induces functional blockade of the γ-aminobutyric acid receptors.
Safety Profile
Poison by subcutaneous route.Moderately toxic by ingestion and intraperitoneal routes.An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits acrid smoke and fumes.
4-Biphenylacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Biphenylacetic acid manufacturers
- Product
- 4-Biphenylacetic acid 5728-52-9
- Price
- US $50.00-500.00/KG
- Min. Order
- 1KG
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-10-10
- Product
- biphenyl-4-ylacetic acid 5728-52-9
- Price
- US $100.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2023-09-04
- Product
- 4-Biphenylacetic acid 5728-52-9
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 1000kg
- Release date
- 2021-09-16