4-Biphenylacetic acid

Product Name: 4-Biphenylacetic acid
CAS No.: 5728-52-9
Chemical Name: 4-Biphenylacetic acid
Synonyms: FELBINAC;Napageln;BIPHENYL-4-ACETIC ACID;[1,1'-BIPHENYL]-4-ACETIC ACID;2-([1,1'-biphenyl]-4-yl)acetic acid;L-141;TraxaM;LY-61017;Seltouch;CI 83544
CBNumber: CB0186272
Molecular Formula: C14H12O2
Formula Weight: 212.24
MOL File: 5728-52-9.mol

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4-Biphenylacetic acid Property

Melting point:: 159-160 °C (lit.)
Boiling point:: 312.08°C (rough estimate)
Density: 1.1035 (rough estimate)
refractive index: 1.6000 (estimate)
storage temp.: 2-8°C
solubility: DMSO: soluble50mg/mL, clear, colorless to yellow
form: Powder
pka: 4.29±0.10(Predicted)
color: Beige
Water Solubility: 39.27mg/L(25 ºC)
Merck: 14,3316
BRN: 1211592
InChI: InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16)
InChIKey: QRZAKQDHEVVFRX-UHFFFAOYSA-N
SMILES: C1(C2=CC=CC=C2)=CC=C(CC(O)=O)C=C1
CAS DataBase Reference: 5728-52-9(CAS DataBase Reference)

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Safety

Hazard Codes: T,Xn
Risk Statements: 23/25-36/37/38-25-36/37/38/63-20/21/22
Safety Statements: 26-36/37/39-45-37/39-28A-26/36/3745/60-20-36
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: DU8229050
Hazard Note: Irritant
HazardClass: 6.1
PackingGroup: III
HS Code: 29163900
Toxicity: LD50 orally in rats: 164 mg/kg (Sloboda, Osterberg)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 196487
Product name: 4-Biphenylacetic acid
Purity: 98%
Packaging: 5g
Price: $60.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: 196487
Product name: 4-Biphenylacetic acid
Purity: 98%
Packaging: 25g
Price: $120
Updated: 2023/01/07

TCI Chemical

Product number: B1278
Product name: 4-Biphenylacetic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $41
Updated: 2024/03/01

TCI Chemical

Product number: B1278
Product name: 4-Biphenylacetic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 250g
Price: $232
Updated: 2024/03/01

Alfa Aesar

Product number: A11749
Product name: 4-Biphenylacetic acid, 98%
Packaging: 50g
Price: $151
Updated: 2023/06/20

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4-Biphenylacetic acid Chemical Properties,Usage,Production

Description

Felbinac Is the active metabolite of the non-steroidal antiinflammatory agent, fenbufen. Applied topically as a gel to joints, it is useful in the symptomatic relief of articular inflammation and pain.

Chemical Properties

Off-white powder

Originator

Lederle (USA)

Uses

Anti-inflammatory, analgesic drug.

Uses

4-Biphenylacetic acid was used in the synthesis of gastrosparing non-steroidal antiinflammatory drug.

Definition

ChEBI: Biphenyl-4-ylacetic acid is a monocarboxylic acid in which one of the alpha-hydrogens is substituted by a biphenyl-4-yl group. An active metabolite of fenbufen, it is used as a topical medicine to treat muscle inflammation and arthritis. It has a role as a non-steroidal anti-inflammatory drug. It is a member of biphenyls and a monocarboxylic acid. It contains a biphenyl-4-yl group. It is functionally related to an acetic acid.

brand name

Dolinac (Wyeth-Ayerst); Flexfree(Wyeth-Ayerst); Napageln (Wyeth-Ayerst); Target (Wyeth-Ayerst); Traxam (Wyeth-Ayerst).

General Description

4-Biphenylacetic acid is a potential non-steroidal antiinflammatory agent and forms solid inclusion complex with β-cyclodextrin. 4-Biphenylacetic acid on interaction with quinolone antibacterial agents induces functional blockade of the γ-aminobutyric acid receptors.

Safety Profile

Poison by subcutaneous route.Moderately toxic by ingestion and intraperitoneal routes.An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits acrid smoke and fumes.

4-Biphenylacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Biphenylacetic acid Suppliers

Americas 1 Australia 1 Austria 1 Belgium 4 Canada 5 China 343 Europe 5 France 2 Germany 10 India 28 Italy 1 Japan 10 Poland 1 Slovakia 1 South Korea 6 Switzerland 3 The Netherlands 1 Turkey 1 Ukraine 1 United Arab Emirates 1 United Kingdom 21 United States 56 Global 503

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View Lastest Price from 4-Biphenylacetic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4-Biphenylacetic acid 5728-52-9
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%min
Supply Ability: 1000kg
Release date: 2021-09-16

Baoji Guokang Bio-Technology Co., Ltd.

Product: 4-Biphenylacetic acid 5728-52-9
Price: US $3055.00/Kg/Drum
Min. Order: 25KG
Purity: 98%
Supply Ability: 1T
Release date: 2021-06-04

Hebei Weibang Biotechnology Co., Ltd

Product: 4-Biphenylacetic acid 5728-52-9
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-14

5728-52-9, 4-Biphenylacetic acidRelated Search:

Phenylacetic acid 4-Biphenylcarboxylic acid Xenyhexenic felbinacethyl cicloprofen xenbucin FLURBIPROFEN AXETIL (R)-(-)-2-FLUORO-ALPHA-METHYL-4-BIPHENYLACETIC ACID 2-FLUORO-ALPHA-METHYL-4-BIPHENYLACETIC ACID FLURBIPROFEN SODIUM (200 MG) Namoxyrate butixirate (S)-Flurbiprofen 2-FLUORO-ALPHA-METHYL-4-BIPHENYLACETIC ACID 4-Biphenylacetic acid BIFEPROFEN 2',4'-difluorobiphenyl-4-acetic acid Fluprofen

4-BIPHENYLACETICABID

Biphenyl-4-acetic acid 97%

4-Biphenylacetic acid/Felbinac

4 -BIPHENYLACETIC ACID 99% BP GRADE

4-BIPHENYL ACETIC ACID 98.5%

4-BIPHENYLACETIC ACID(METHOXYMETHYL)-1,1''-BIPHENYL

Napageln

4-Biphenylacetic acid ,99%

L-141

LJC-10141

LY-61017

4-Biphenylacetic aci

4-BIPHENYLYLACETIC ACID

P-BIPHENYLYLACETIC ACID

(Biphenyl-4-yl)acetic acid 97%

4-Biphenylacetic acid, 98% 10GR

NSC 16284

Seltouch

TraxaM

4-BIPHENYLYLACETIC ACID FOR SYNTHESIS

Biphenyl acetic acid(Felbinac)

2-([1,1'-biphenyl]-4-yl)acetic acid

Biphenyl-4-yl-acetic acid

BIPHENYL-4-ACETIC ACID

FELBINAC

CI 83544

4-PHENYLPHENYLACETIC ACID

4-CARBOXYMETHYLBIPHENYL

4-BIPHENYLACETIC ACID

[1,1'-BIPHENYL]-4-ACETIC ACID

4-Diphenylacetic Acid

P-BIPHENYLACETIC ACID

RARECHEM AL BO 0343

Felbinac(4-BiphenylaceticAcid)

4-Biphenylaceticacid,98+%

biphenyl acetic acide

4-biphenyl acetic acide

4-bisphenylacetic acid ( Felbinac）

Flurbiprofen-d3 (2-Fluoro-a-trideuteromethyl-[1,1&rsquo

Felbinac CRS

4-Biphenylacetic Acid &gt

4-Biphenylessigsaeure

Talc 14807-96-6

Biphenyl monoacetic acid

Felbinac Crude

4-Biphenylacetic Methyl Ether

4-Biphenylacetic Acid, ≥ 97.0%

2-([1,1'-biphenyl]-4-yl)acetic acid

5728-52-9

57285-52-9

572-52-9

40728-52-9

C14H11O2

C6H5C6H4CH2CO2H

Organic Building Blocks

Building Blocks

C13 to C42+

Carbonyl Compounds