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H-ALA-NHME HCL

Product Name
H-ALA-NHME HCL
CAS No.
61275-22-7
Chemical Name
H-ALA-NHME HCL
Synonyms
H-Ala-NHMe;L-Ala-NHMe·HCl;H-ALA-NHME HCL;ALANINE-NHME HCL;N-methyl-L-alaninamide;H-Ala-NHMe hydrochloride;L-Alanine MethylaMide HCl;L-ALANINE METHYLAMIDE HYDROCHLORIDE;L-ALANINE N-METHYLAMIDE HYDROCHLORIDE;propanamide, 2-amino-N-methyl-, (2S)-
CBNumber
CB0188014
Molecular Formula
C4H11ClN2O
Formula Weight
138.6
MOL File
61275-22-7.mol
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H-ALA-NHME HCL Property

Melting point:
218-220 °C(Solv: methanol (67-56-1); ethyl ether (60-29-7))
storage temp. 
Inert atmosphere,Room Temperature
form 
solid
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A614020
Product name
H-Ala-NHMehydrochloride
Packaging
500mg
Price
$75
Updated
2021/12/16
Usbiological
Product number
451581
Product name
H-Ala-NHMe HCl
Packaging
100mg
Price
$305
Updated
2021/12/16
AK Scientific
Product number
W7355
Product name
L-Ala-NHMe·HCl
Packaging
5g
Price
$334
Updated
2021/12/16
Chem-Impex
Product number
05833
Product name
L-Alaninemethylamidehydrochloride,98%(HPLC)
Purity
98%(HPLC)
Packaging
5G
Price
$358.4
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA48633
Product name
L-Alanine methylamide hydrochloride
Packaging
5G
Price
$581.3
Updated
2021/12/16
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H-ALA-NHME HCL Chemical Properties,Usage,Production

Chemical Properties

White powder or solid

Uses

H-Ala-NHMe HCl

Synthesis

1115-59-9

61275-22-7

The general procedure for the synthesis of (S)-2-amino-N-methylpropionamide hydrochloride from L-alanine ethyl ester hydrochloride was as follows: ethyl L-alanine ethyl ester hydrochloride (8.1 g, 52.4 mmol) was dissolved in ethanol-methylamine solution (36 mL, 289 mmol), and the reaction was stirred for 97 hours. Upon completion of the reaction, the solvent was removed by evaporation. The residue was dissolved in 4 M potassium carbonate solution (30 mL) and saturated sodium bicarbonate solution (20 mL) and subsequently extracted with chloroform (5 × 25 mL). The organic phases were combined, dried over sodium carbonate and evaporated to give the crude (S)-2-amino-N-methylpropionamide as a red oil (3.62 g, 35.5 mmol, 68% yield). The free amine (1.9 g, 18.5 mmol) was dissolved in ether (200 mL) and treated by passing hydrogen chloride gas for 10 min. At the end of the reaction, the product was collected by filtration and washed with ether to afford (S)-2-amino-N-methylpropionamide hydrochloride as clarified crystals (2.2 g, 16.0 mmol, 86% yield). The product was further purified by recrystallization from ethanol and hexane; melting point 213-215 °C; [α]D25 +19.6 (c 0.1, CH3OH); νmax (NaCl disk)/cm-1 3408, 1674, 1514, 1417, 1275, 1169; δH (400 MHz, D2O) 3.85 (1H, q, J 7.1 Hz, CH), 2.60 (3H, s, NCH3), 1.32 (3H, d, J 7.1 Hz, CCH3); δC (100 MHz, D2O) 174.1 (C), 51.2 (CH), 28.5 (CH3), 19.2 (CH3).

References

[1] Tetrahedron, 2011, vol. 67, # 23, p. 4263 - 4267

H-ALA-NHME HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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H-ALA-NHME HCL Suppliers

China 42 India 2 Japan 1 United Kingdom 1 United States 9 Global 55
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Sichuan Ampebiochem Co., Ltd.
Tel
028-65294243 13981822079;18682730901
Email
sales@ampebiochem.com
Country
China
ProdList
1000
Advantage
58
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Chengdu Chuangkecheng Biological Technology Co., Ltd.
Tel
028-028-0000000 13008177686
Fax
15928581901
Email
sales@ckcbiotech.com
Country
China
ProdList
904
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60

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  • H-ALA-NHME HCL
  • L-ALANINE METHYLAMIDE HYDROCHLORIDE
  • L-ALANINE N-METHYLAMIDE HYDROCHLORIDE
  • ALANINE-NHME HCL
  • N~1~-methyl-L-alaninamide hydrochloride
  • propanamide, 2-amino-N-methyl-, (2S)-
  • H-Ala-NHMe
  • (S)-2-AMino-N-MethylpropanaMide hydrochloride
  • L-Alanine MethylaMide HCl
  • L-Ala-NHMe·HCl
  • L-Alanine methylamide hydrochloride≥ 98% (HPLC)
  • N-methyl-L-alaninamide
  • H-Ala-NHMe hydrochloride
  • 61275-22-7