Methyl 3-amino-4-methylthiophene-2-carboxylate

Product Name: Methyl 3-amino-4-methylthiophene-2-carboxylate
CAS No.: 85006-31-1
Chemical Name: Methyl 3-amino-4-methylthiophene-2-carboxylate
Synonyms: 3-AMINO-4-METHYL-2-THIOPHENECARBOXYLIC ACID METHYL ESTER;3-Amino Articaine;3-AMINO-4-METHYLTHIOPHENECARBOXYLIC ACID METHYL ESTER;M3A4MT2C;Articaine-002;Articaine Impurity I;Articaine Impurity 9;LABOTEST-BB LT00453517;Articaine EP Impurity I;Articaine intermediate E
CBNumber: CB0189112
Molecular Formula: C7H9NO2S
Formula Weight: 171.22
MOL File: 85006-31-1.mol

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Methyl 3-amino-4-methylthiophene-2-carboxylate Property

Melting point:: 85-88 °C (lit.)
Boiling point:: 318.6±37.0 °C(Predicted)
Density: 1.264±0.06 g/cm3(Predicted)
Flash point:: >100°C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 1.71±0.10(Predicted)
form: Solid
color: Pale Yellow
Water Solubility: 1g/L at 35℃
BRN: 973196
InChIKey: YICRPERKKBDRSP-UHFFFAOYSA-N
LogP: 1.28
CAS DataBase Reference: 85006-31-1(CAS DataBase Reference)
NIST Chemistry Reference: Methyl 3-amino-4-methylthiophene-2-carboxylate(85006-31-1)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25-22
WGK Germany: 2
Hazard Note: Irritant
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 546658
Product name: Methyl 3-amino-4-methylthiophene-2-carboxylate
Purity: 97%
Packaging: 5g
Price: $33.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: 546658
Product name: Methyl 3-amino-4-methylthiophene-2-carboxylate
Purity: 97%
Packaging: 25g
Price: $127
Updated: 2024/03/01

TCI Chemical

Product number: M1772
Product name: Methyl 3-Amino-4-methylthiophene-2-carboxylate
Purity: >98.0%(GC)
Packaging: 5g
Price: $29
Updated: 2024/03/01

TCI Chemical

Product number: M1772
Product name: Methyl 3-Amino-4-methylthiophene-2-carboxylate
Purity: >98.0%(GC)
Packaging: 25g
Price: $101
Updated: 2024/03/01

Alfa Aesar

Product number: A10115
Product name: Methyl 3-amino-4-methylthiophene-2-carboxylate, 98%
Packaging: 5g
Price: $59.2
Updated: 2021/12/16

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Methyl 3-amino-4-methylthiophene-2-carboxylate Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

Methyl 3-Amino-4-methylthiophene-2-carboxylate is a versatile reactant used in various syntheses. It is used in the preparation of (oxalylamino)benzoic acids and (carboxyheteroarylamino)oxalic acids as selective and orally bioavailable nonpeptide inhibitors of protein-tyrosine phosphatase 1B.

Application

methyl 3-amino-4-methylthiophene-2-carboxylate is the starting material used in the synthesis of the local anesthetic articaine.
7-Methylthieno[3,2-d]pyrimidin-4(3H)-one was prepared using methyl 3-amino-4-methylthiophene-2-carboxylate.
The reaction of 4-bromotoluene (0.171 g, 1 mmol), methyl 3-amino-4-methylthiophene-2-carboxylate(0.342 g, 2 mmol) and KOAc (0.196 g, 2 mmol) in the presence of PdCl(C3H5)(dppb) (12.2 mg, 0.02mmol) in DMAc at 120 °C affords the corresponding Methyl 3-amino-4-methyl-5-p-tolylthiophene-2-carboxylate in 81% (0.212 g) isolated yield.

Definition

ChEBI: Methyl 3-amino-4-methylthiophene-2-carboxylate is a thiophenecarboxylic acid.

Methyl 3-amino-4-methylthiophene-2-carboxylate Preparation Products And Raw materials

Raw materials

Methyl thioglycolate Sodium hydride Ethanol Hydroxylamine hydrochloride Methyl methacrylate

Preparation Products

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Methyl 3-amino-4-methylthiophene-2-carboxylate Suppliers

Americas 1 Belgium 1 China 286 Europe 3 France 4 Germany 8 India 20 Italy 2 Japan 2 Slovakia 3 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 17 United States 43 Global 394

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View Lastest Price from Methyl 3-amino-4-methylthiophene-2-carboxylate manufacturers

Hebei Duling International Trade Co. LTD

Product: Methyl 3-amino-4-methylthiophene-2-carboxylate 85006-31-1
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000 Ton
Release date: 2022-11-15

Shaanxi Dideu Medichem Co. Ltd

Product: Methyl 3-amino-4-methylthiophene-2-carboxylate 85006-31-1
Price: US $1.00-1.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 50tons
Release date: 2020-04-22

Hebei Xinsheng New Material Technology Co., LTD.

Product: Methyl 3-amino-4-methylthiophene-2-carboxylate 85006-31-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 20 tons
Release date: 2023-09-15

85006-31-1, Methyl 3-amino-4-methylthiophene-2-carboxylateRelated Search:

Methyl 4-(bromomethyl)benzoate Methyl anthranilate METSULFURON METHYL Basic Violet 1 Methyl salicylate Methanol Kresoxim-methyl Glycine Methylparaben Methyl 4-methylbenzoate 3-AMINOTHIOPHENE 2-Methylthiophene Methyl acrylate RESMETHRIN Tribenuron methyl Methyl carbamate Methyl METHYL 3-AMINO-4-CYANOTHIOPHENE-2-CARBOXYLATE

M3A4MT2C

METHYL 3-AMINO-4-METHYLTHIOPHENE-2-CARBOXYLATE

Methyl 3-amino-4-methyl-2-thenoate

METHYL 3-AMINO-4-METHYL-2-THIOPHENECARBOXYLATE

LABOTEST-BB LT00453517

3-AMINO-4-METHYL-2-THIOPHENECARBOXYLIC ACID METHYL ESTER

3-AMINO-4-METHYLTHIOPHENE-2-CARBOXYLIC ACID METHYL ESTER

3-AMINO-4-METHYLTHIOPHENECARBOXYLIC ACID METHYL ESTER

Methyl 3-Amino-4-Methylthiophen-2-Carboxylate

METHYL 3-AMINO-4-METHYLTHIOPHENE-2-CARBO

3-Amino-4-Methyl-2-ThiophenecarboxylicMethylester

Articaine intermediate E

3-Amino-2-methoxycarbonyl-4-methylthiophene

3-Amino-2-carbomethoxy-4-methylthiophen

3-Amino-4-methylthiophene-2-carboxylic

2-Thiophenecarboxylic acid, 3-amino-4-methyl-, methyl ester

4-Methyl-3-aminothiophene-2-carboxylic acid methyl ester

Methyl 3-amino-4-methylthiophene-2-carboxylate ,99%

3-AMino-4-Methyl-2-thiophene carboxylic acid ester

3-Amino-2-(methoxycarbonyl)-4-methylthiophene, Methyl 3-amino-4-methyl-2-thenoate

Articaine IMpurity I (Methyl 3-AMino-4-Methylthiophene-2-Carboxylate)

Methyl 3-AMino-4-Methylthiophene-2-carboxylate , 98.0%(GC)

Methyl3-amino-4-methylthiophene-2-carboxylate,98%

Methyl 3-amino-4-methylthiophene-2-carboxylate(Articaine Intermediates)

3-AMINO 4-METHYL-2-THIOPHENE CARBOXYLICACID METHYL ESTER IMPORTED VIDE B/E 3189721/ 06.11.2015][CLEAR AGAINST ADVANCE L

Articaine Impurity 9(Articaine EP Impurity I）

Articaine EP Impurity I

Methyl3-Amino-4-methylthiophene-2-carboxylate&gt

3-Amino Articaine

Articaine-002

Articaine Impurity I

3- amino-4-methyl thiophene - 2-carboxylate, methyl ester

Methyl 3-amino-4-methylthiophene-2-carboxylate ISO 9001：2015 REACH

Articaine Impurities1819

Articaine Impurity 9

Articaine Hydrochloride Impurity I

Articaine Hydrochloride EP Impurity I

85006-31-1

C7H9SNO2

Heterocyclic Building Blocks

Thiophenes

Building Blocks

Thiophenes & Benzothiophenes

Building Blocks

C7 to C9

Chemical Synthesis

Heterocyclic Building Blocks

Thiophenes

Thiophen

Esters

Thiophenes & Benzothiophenes

Thiophene&Benzothiophene

Organic acids

API intermediates

1